TOP 100 热点文章

题名 第一作者 访问量
Edoxaban versus Warfarin in Patients with Atrial Fibrillation Giugliano, Robert P. 2154
Nitrogen-Doped Graphene as Efficient Metal-Free Electrocatalyst for Oxygen Reduction in Fuel Cells Qu, Liangti 1952
Aetiology of severe community acquired pneumonia in adults identified by combined detection methods: a multi-centre prospective study in China Qu, Jieming 1931
THE VALUE OF ADA LEVEL AND MONOCYTE RATIO IN PLEURAL EFFUSION TO DIFFERENTIATE TUBERCULOUS PLEURISY FROM MALIGNANT EFFUSION AND EMPYEMA Nan, Hailin 1912
Proteomic and Metabolomic Characterization of COVID-19 Patient Sera Shen, Bo 1899
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Klionsky, Daniel J. 1876
Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding Lu, Roujian 1823
Pan-Cancer Analysis Predicts FOXS1 as a Key Target in Prognosis and Tumor Immunotherapy Liu, Yunqiang 1740
Finishing the euchromatic sequence of the human genome Collins, F.S. 1709
MR Imaging Provides Practical Information for Preoperative Assessment of Radial Polydactyly with Bifurcation at the Metacarpophalangeal Joint Level Du, Meimei 1040
Andrographolide contributes to the attenuation of cardiac hypertrophy by suppressing endoplasmic reticulum stress Tian, Qingxin 924
Reviewing the mechanism of propofol addiction Zhong, Tianhao 863
Phylogenetic analysis and virulence characteristics of methicillin-resistant Staphylococcus aureus ST764-SCCmec II: an emerging hypervirulent clone ST764-t1084 in China Xiao, Yanghua 857
COVID-19 vaccine hesitancy between family decision-makers and non-decision-makers among college teachers Xu, Rong 813
Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries The International Surgical Outcomes Study group Pearse, Rupert M. 759
Chlorogenic acid alleviates hypoxic-ischemic brain injury in neonatal mice Li, Lu-Yao 724
Identification of methicillin-resistant Staphylococcus aureus ST8 isolates in China with potential high virulence Wang, Xinyi 713
Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome Schwartz G.G. 706
SARM1 Promotes Neurodegeneration and Memory Impairment in Mouse Models of Alzheimer's Disease Miao, Xuemeng 689
Functions and mechanisms of cytosolic phospholipase A2 in central nervous system trauma. Zhang, Hao-Jie 668
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 Klionsky, Daniel J. 661
Macrophage membrane-biomimetic adhesive polycaprolactone nanocamptothecin for improving cancer-targeting efficiency and impairing metastasis Ying, Kangkang 654
Mesenchymal Stem Cells in Fibrotic Disease El Agha, Elie 638
APPLICATION OF STATE-OF-THE-ART COMPUTER TECHNOLOGY TO STRENGTH TRAINING IN TENNIS INSTRUCTION Pei, Yanming 635
Vertically aligned BCN nanotubes as efficient metal-free electrocatalysts for the oxygen reduction reaction: A synergetic effect by co-doping with boron and nitrogen Wang, Shuangyin 630
Diabetic Downregulation of Nrf2 Activity via ERK Contributes to Oxidative Stress-Induced Insulin Resistance in Cardiac Cells In Vitro and In Vivo Tan, Yi 626
Classification of Echocardiographic Standard Views Using a Hybrid Attention-based Approach Ye, Zi 615
Development of a rapid UPLC-MS/MS method for the determination of toddalolactone in mouse blood and its application in pharmacokinetics Zhou, Jing 614
科技伦理的祛魅、统合、自觉及其价值选择——基于“高概念”主张引入人工智能伦理研究的省察 刘博京 609
p Accepting Immunotherapy After Multiline Treatment Failure: An Exploration of the Anxiety and Depression in Patients with Advanced Cancer Experience Xie, Qingqing 608
Effect of Regional vs General Anesthesia on Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery The RAGA Randomized Trial Li, Ting 608
CRRT上机血流速对ICU患者血压的影响 陈王峰 607
基于深度学习的睑板腺功能障碍图像分析模型研究和评价 张祖辉 606
p40、TTF-Ⅰ、p63、CK5/6在肺腺癌和肺鳞癌中的表达及其意义 焦立卓 606
Neoantigen-reactive T cells exhibit effective anti-tumor activity against colorectal cancer Yu, Yaojun 604
Diagnostic value of endobronchial ultrasound elastography for differentiating benign and malignant hilar and mediastinal lymph nodes: a systematic review and meta-analysis Wu, Jiangfeng 603
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals Lee, James J. 603
Why do parents willingness-to-pay to vaccinate their children against COVID-19? A real-world evidence in Taizhou, China Tung, Tao-Hsin 598
Letter to the Editor: Obesity as a risk factor for greater severity of COVID-19 in patients with metabolic associated fatty liver disease Kenneth I Zheng 596
ADIPONECTIN INHIBITS OSTEOCLAST DIFFERENTIATION INDUCED BY RANKL AND ITS MECHANISM Li, Shi 593
移动远程眩晕症诊断平台的构建 陈蓓蓓 591
Newly-Designed Complex Ternary Pt/PdCu Nanoboxes Anchored on Three-Dimensional Graphene Framework for Highly Efficient Ethanol Oxidation Hu, Chuangang 587
Cerebral ischemia-reperfusion-induced autophagy protects against neuronal injury by mitochondrial clearance Zhang, Xiangnan 585
Endoplasmic Reticulum Stress and Lipid Metabolism Zhou, Huiping 585
LINC00518 affects the proliferation, invasion and migration of cutaneous malignant melanoma cells via miR-526b-3p/EIF5A2 axis Xu, Jie 583
Long non-coding RNA LINC00673 promotes breast cancer proliferation and metastasis through regulating B7-H6 and epithelial-mesenchymal transition (vol 8, pg 1273, 2018) Xia, Erjie 582
Engineering Bioactive Self-Healing Antibacterial Exosomes Hydrogel for Promoting Chronic Diabetic Wound Healing and Complete Skin Regeneration Wang, Chenggui 580
Ultrasound-guided radial artery catheterization at different sites: a prospective and randomized study Wu X.-L. 578
Ferroptosis, a new form of cell death, and its relationships with tumourous diseases Yu, Haitao 578
Letter to the Editor: Obesity as a risk factor for greater severity of COVID-19 in patients with metabolic associated fatty liver disease Zheng, Kenneth I. 578
Intra-articular drug delivery systems for osteoarthritis therapy: shifting from sustained release to enhancing penetration into cartilage Huang, Huirong 577
Restricted Feeding Resets Endogenous Circadian Rhythm in Female Mice Under Constant Darkness Yue Mei 577
A Graphene-Based Sensor Array for High-Precision and Adaptive Target Identification with Ensemble Aptamers Pei, Hao 572
Minimally Invasive versus Abdominal Radical Hysterectomy for Cervical Cancer Ramirez, Pedro T. 572
Assessing the drug resistance profiles of oral probiotic lozenges Wang, Yi 571
长链非编码RNA-H19介导的自噬在垂体腺瘤发生发展中的机制研究 李群 570
宋代胥吏之弊及其防治机制研究 武小平 569
Nitrogen-Doped Graphene Foams as Metal-Free Counter Electrodes in High-Performance Dye-Sensitized Solar Cells Xue, Yuhua 562
基于CiteSpace的蛹虫草研究进展可视化分析 朱碧纯 560
褪黑素降解急性髓细胞白血病细胞AML1-ETO融合蛋白的机制研究 刘旭玲 560
Association Between Body Mass Index and Female Infertility in the United States: Data from National Health and Nutrition Examination Survey 2013-2018 Zhu, Lei 557
Neoadjuvant Chemoradiotherapy Followed by Surgery Versus Surgery Alone for Locally Advanced Squamous Cell Carcinoma of the Esophagus (NEOCRTEC5010): A Phase III Multicenter, Randomized, Open-Label Clinical Trial Yang, Hong 557
一种抗菌水凝胶载药微球的制备及其在细胞扩增中的应用 沈贤 557
SPINK2 is a prognostic biomarker related to immune infiltration in acute myeloid leukemia Chen, Xiaohe 556
Three-dimensional (3D) printed scaffold and material selection for bone repair Zhang, Lei 555
Endovascular Thrombectomy with or without Intravenous Alteplase in Acute Stroke Yang, Pengfei 553
One-pot synthesis of N-doped carbon dots with tunable luminescence properties Zhang, Yan-Qing 551
Effectiveness and Tolerability of NSAIDs in the Prophylaxis of Pancreatitis After Endoscopic Retrograde Cholangiopancreatography: A Systematic Review and Meta-Analysis Zheng, Ming-Hua 550
MRI多模态成像在UTMD联合CA-(Q-D-lip)精确示踪和治疗胶质瘤中的价值 郑汉朋 548
Dynamic changes of platelets before and after surgery predict the prognosis of patients with operable non-small cell lung cancer Yang, Wei 546
Programmable Engineering of a Biosensing Interface with Tetrahedral DNA Nanostructures for Ultrasensitive DNA Detection Lin, Meihua 543
Connecting the Dots: The Cerebral Lymphatic System as a Bridge Between the Central Nervous System and Peripheral System in Health and Disease Zhao, Hongxiang 543
Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis Lu, Jianxin 542
Tumor protein P63 Regulated 1 contributes to inflammation and cell proliferation of cystitis glandularis through regulating the NF-kB/cyclooxygenase-2/ prostaglandin E2 axis Hong, Tao 539
New insights into the classification and nomenclature of cortical GABAergic interneurons Defelipe, Javier 538
Surface-Adaptive Gold Nanoparticles with Effective Adherence and Enhanced Photothermal Ablation of Methicillin-Resistant Staphylococcus aureus Biofilm Hu, Dengfeng 537
临床医学教育的博客化教学与管理 王斌 534
The relationship between phubbing and the depression of primary and secondary school teachers: A moderated mediation model of rumination and job burnout Liu, Jing 533
A Matrigel-based 3D construct of SH-SY5Y cells models the α-synuclein pathologies of Parkinson's disease Li, Zhao-Feng 532
Multi-population differential evolution-assisted Harris hawks optimization: Framework and case studies Chen, Hao 531
COVID-19 and Liver Dysfunction: Current Insights and Emergent Therapeutic Strategies Feng, Gong 531
Endoplasmic Reticulum Stress and Atherosclerosis Zhou, Huiping 529
Blockade of myeloid differentiation 2 attenuates diabetic nephropathy by reducing activation of the renin-angiotensin system in mouse kidneys Wang, Yi 526
超长效可控缓释介孔-透明质酸杂化靶向抗菌纳米材料及其制备方法、用途 邓辉 525
Among simple non-invasive scores, Pro-C3 and ADAPT best exclude advanced fibrosis in Asian patients with MAFLD Tang, Liang-Jie 524
Efficacy of Curcumin for Wound Repair in Diabetic Rats/Mice: A Systematic Review and Meta-analysis of Preclinical Studies Li, Yuan 522
牙缺损伴牙颌畸形行正畸修复联合治疗的临床研究 潘孝义 521
Efficacy of PD-1 or PD-L1 inhibitors and PD-L1 expression status in cancer: meta-analysis Shen, Xian 520
全面二孩政策前后早产儿发生情况及结局分析 朱丹丹 518
Design and optimize N-substituted EF24 as effective and low toxicity NF-kappa B inhibitor for lung cancer therapy via apoptosis-to-pyroptosis switch Chen, Liping 513
一种聚乳酸/纳米羟基磷灰石复合微球包裹的硫酸庆大霉素及其制备方法 陈浩 512
AKT1/HK2 Axis-mediated Glucose Metabolism: A Novel Therapeutic Target of Sulforaphane in Bladder Cancer Huang, Lei 510
Bioactive degradable surgical suture and preparation method thereof HE, HUACHENG 510
Blockade of adenosine A(2A) receptor alleviates cognitive dysfunction after chronic exposure to intermittent hypoxia in mice Li, Xiu-Cui 509
Oncocytic tumors are marked by enhanced mitochondrial content and mtDNA mutations of complex I in Chinese patients Lyu, Lihua 508
The role of external signal regulated kinase and transforming growth factor β1 in asthma airway remodeling and regulation of glucocorticoids Xiao-jun Guan 507
Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome Shi, Yongyong 503
Innate Immunity in Age-Related Macular Degeneration Zhang, Yikui 503
Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series Xu, Xiao-Wei 501
A novel raiometric fluorescence probe based on silicon quantum dots and copper nanoclusters for visual assay of l-cysteine in milks Ma, Yange 500