TOP 100 热点文章

题名 第一作者 访问量
Edoxaban versus Warfarin in Patients with Atrial Fibrillation Giugliano, Robert P. 3278
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Klionsky, Daniel J. 2541
Nitrogen-Doped Graphene as Efficient Metal-Free Electrocatalyst for Oxygen Reduction in Fuel Cells Qu, Liangti 2214
Aetiology of severe community acquired pneumonia in adults identified by combined detection methods: a multi-centre prospective study in China Qu, Jieming 2202
THE VALUE OF ADA LEVEL AND MONOCYTE RATIO IN PLEURAL EFFUSION TO DIFFERENTIATE TUBERCULOUS PLEURISY FROM MALIGNANT EFFUSION AND EMPYEMA Nan, Hailin 2179
Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding Lu, Roujian 2096
Proteomic and Metabolomic Characterization of COVID-19 Patient Sera Shen, Bo 2094
Finishing the euchromatic sequence of the human genome Collins, F.S. 1975
Pan-Cancer Analysis Predicts FOXS1 as a Key Target in Prognosis and Tumor Immunotherapy Liu, Yunqiang 1841
MR Imaging Provides Practical Information for Preoperative Assessment of Radial Polydactyly with Bifurcation at the Metacarpophalangeal Joint Level Du, Meimei 1109
Andrographolide contributes to the attenuation of cardiac hypertrophy by suppressing endoplasmic reticulum stress Tian, Qingxin 1054
Phylogenetic analysis and virulence characteristics of methicillin-resistant Staphylococcus aureus ST764-SCCmec II: an emerging hypervirulent clone ST764-t1084 in China Xiao, Yanghua 990
Reviewing the mechanism of propofol addiction Zhong, Tianhao 971
Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries The International Surgical Outcomes Study group Pearse, Rupert M. 919
COVID-19 vaccine hesitancy between family decision-makers and non-decision-makers among college teachers Xu, Rong 917
Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome Schwartz G.G. 864
Identification of methicillin-resistant Staphylococcus aureus ST8 isolates in China with potential high virulence Wang, Xinyi 846
Chlorogenic acid alleviates hypoxic-ischemic brain injury in neonatal mice Li, Lu-Yao 842
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 Klionsky, Daniel J. 816
SARM1 Promotes Neurodegeneration and Memory Impairment in Mouse Models of Alzheimer's Disease Miao, Xuemeng 785
Chronobiology of the Tumor Microenvironment: Implications for Therapeutic Strategies and Circadian-Based Interventions Li, Dengxiong 784
Macrophage membrane-biomimetic adhesive polycaprolactone nanocamptothecin for improving cancer-targeting efficiency and impairing metastasis Ying, Kangkang 759
Functions and mechanisms of cytosolic phospholipase A2 in central nervous system trauma. Zhang, Hao-Jie 758
Mesenchymal Stem Cells in Fibrotic Disease El Agha, Elie 755
Vertically aligned BCN nanotubes as efficient metal-free electrocatalysts for the oxygen reduction reaction: A synergetic effect by co-doping with boron and nitrogen Wang, Shuangyin 748
APPLICATION OF STATE-OF-THE-ART COMPUTER TECHNOLOGY TO STRENGTH TRAINING IN TENNIS INSTRUCTION Pei, Yanming 745
Diabetic Downregulation of Nrf2 Activity via ERK Contributes to Oxidative Stress-Induced Insulin Resistance in Cardiac Cells In Vitro and In Vivo Tan, Yi 731
Development of a rapid UPLC-MS/MS method for the determination of toddalolactone in mouse blood and its application in pharmacokinetics Zhou, Jing 725
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals Lee, James J. 724
基于深度学习的睑板腺功能障碍图像分析模型研究和评价 张祖辉 724
p Accepting Immunotherapy After Multiline Treatment Failure: An Exploration of the Anxiety and Depression in Patients with Advanced Cancer Experience Xie, Qingqing 721
Neoantigen-reactive T cells exhibit effective anti-tumor activity against colorectal cancer Yu, Yaojun 718
Why do parents willingness-to-pay to vaccinate their children against COVID-19? A real-world evidence in Taizhou, China Tung, Tao-Hsin 716
Letter to the Editor: Obesity as a risk factor for greater severity of COVID-19 in patients with metabolic associated fatty liver disease Kenneth I Zheng 716
Classification of Echocardiographic Standard Views Using a Hybrid Attention-based Approach Ye, Zi 714
Diagnostic value of endobronchial ultrasound elastography for differentiating benign and malignant hilar and mediastinal lymph nodes: a systematic review and meta-analysis Wu, Jiangfeng 712
p40、TTF-Ⅰ、p63、CK5/6在肺腺癌和肺鳞癌中的表达及其意义 焦立卓 712
Effect of Regional vs General Anesthesia on Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery The RAGA Randomized Trial Li, Ting 711
科技伦理的祛魅、统合、自觉及其价值选择——基于“高概念”主张引入人工智能伦理研究的省察 刘博京 705
Letter to the Editor: Obesity as a risk factor for greater severity of COVID-19 in patients with metabolic associated fatty liver disease Zheng, Kenneth I. 703
Restricted Feeding Resets Endogenous Circadian Rhythm in Female Mice Under Constant Darkness Yue Mei 703
ADIPONECTIN INHIBITS OSTEOCLAST DIFFERENTIATION INDUCED BY RANKL AND ITS MECHANISM Li, Shi 702
Cerebral ischemia-reperfusion-induced autophagy protects against neuronal injury by mitochondrial clearance Zhang, Xiangnan 693
Engineering Bioactive Self-Healing Antibacterial Exosomes Hydrogel for Promoting Chronic Diabetic Wound Healing and Complete Skin Regeneration Wang, Chenggui 691
Newly-Designed Complex Ternary Pt/PdCu Nanoboxes Anchored on Three-Dimensional Graphene Framework for Highly Efficient Ethanol Oxidation Hu, Chuangang 691
Long non-coding RNA LINC00673 promotes breast cancer proliferation and metastasis through regulating B7-H6 and epithelial-mesenchymal transition (vol 8, pg 1273, 2018) Xia, Erjie 684
Ferroptosis, a new form of cell death, and its relationships with tumourous diseases Yu, Haitao 682
LINC00518 affects the proliferation, invasion and migration of cutaneous malignant melanoma cells via miR-526b-3p/EIF5A2 axis Xu, Jie 679
Minimally Invasive versus Abdominal Radical Hysterectomy for Cervical Cancer Ramirez, Pedro T. 679
Intra-articular drug delivery systems for osteoarthritis therapy: shifting from sustained release to enhancing penetration into cartilage Huang, Huirong 677
A Graphene-Based Sensor Array for High-Precision and Adaptive Target Identification with Ensemble Aptamers Pei, Hao 676
基于CiteSpace的蛹虫草研究进展可视化分析 朱碧纯 675
Ultrasound-guided radial artery catheterization at different sites: a prospective and randomized study Wu X.-L. 673
Endoplasmic Reticulum Stress and Lipid Metabolism Zhou, Huiping 673
Assessing the drug resistance profiles of oral probiotic lozenges Wang, Yi 665
CRRT上机血流速对ICU患者血压的影响 陈王峰 662
Endovascular Thrombectomy with or without Intravenous Alteplase in Acute Stroke Yang, Pengfei 661
MRI多模态成像在UTMD联合CA-(Q-D-lip)精确示踪和治疗胶质瘤中的价值 郑汉朋 660
Three-dimensional (3D) printed scaffold and material selection for bone repair Zhang, Lei 658
Effectiveness and Tolerability of NSAIDs in the Prophylaxis of Pancreatitis After Endoscopic Retrograde Cholangiopancreatography: A Systematic Review and Meta-Analysis Zheng, Ming-Hua 657
Nitrogen-Doped Graphene Foams as Metal-Free Counter Electrodes in High-Performance Dye-Sensitized Solar Cells Xue, Yuhua 654
一种抗菌水凝胶载药微球的制备及其在细胞扩增中的应用 沈贤 654
Neoadjuvant Chemoradiotherapy Followed by Surgery Versus Surgery Alone for Locally Advanced Squamous Cell Carcinoma of the Esophagus (NEOCRTEC5010): A Phase III Multicenter, Randomized, Open-Label Clinical Trial Yang, Hong 652
Association Between Body Mass Index and Female Infertility in the United States: Data from National Health and Nutrition Examination Survey 2013-2018 Zhu, Lei 651
Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis Lu, Jianxin 649
New insights into the classification and nomenclature of cortical GABAergic interneurons Defelipe, Javier 648
Dynamic changes of platelets before and after surgery predict the prognosis of patients with operable non-small cell lung cancer Yang, Wei 645
Blockade of myeloid differentiation 2 attenuates diabetic nephropathy by reducing activation of the renin-angiotensin system in mouse kidneys Wang, Yi 645
Connecting the Dots: The Cerebral Lymphatic System as a Bridge Between the Central Nervous System and Peripheral System in Health and Disease Zhao, Hongxiang 644
移动远程眩晕症诊断平台的构建 陈蓓蓓 643
One-pot synthesis of N-doped carbon dots with tunable luminescence properties Zhang, Yan-Qing 641
Programmable Engineering of a Biosensing Interface with Tetrahedral DNA Nanostructures for Ultrasensitive DNA Detection Lin, Meihua 638
宋代胥吏之弊及其防治机制研究 武小平 638
临床医学教育的博客化教学与管理 王斌 636
Surface-Adaptive Gold Nanoparticles with Effective Adherence and Enhanced Photothermal Ablation of Methicillin-Resistant Staphylococcus aureus Biofilm Hu, Dengfeng 635
SPINK2 is a prognostic biomarker related to immune infiltration in acute myeloid leukemia Chen, Xiaohe 634
Among simple non-invasive scores, Pro-C3 and ADAPT best exclude advanced fibrosis in Asian patients with MAFLD Tang, Liang-Jie 630
超长效可控缓释介孔-透明质酸杂化靶向抗菌纳米材料及其制备方法、用途 邓辉 630
Efficacy of Curcumin for Wound Repair in Diabetic Rats/Mice: A Systematic Review and Meta-analysis of Preclinical Studies Li, Yuan 628
A Matrigel-based 3D construct of SH-SY5Y cells models the α-synuclein pathologies of Parkinson's disease Li, Zhao-Feng 628
仿生RES捕获纳米药物靶向调控巨噬细胞极化治疗骨关节炎的机制研究 寇龙发 627
Multi-population differential evolution-assisted Harris hawks optimization: Framework and case studies Chen, Hao 625
长链非编码RNA-H19介导的自噬在垂体腺瘤发生发展中的机制研究 李群 624
COVID-19 and Liver Dysfunction: Current Insights and Emergent Therapeutic Strategies Feng, Gong 619
Efficacy of PD-1 or PD-L1 inhibitors and PD-L1 expression status in cancer: meta-analysis Shen, Xian 616
AKT1/HK2 Axis-mediated Glucose Metabolism: A Novel Therapeutic Target of Sulforaphane in Bladder Cancer Huang, Lei 615
褪黑素降解急性髓细胞白血病细胞AML1-ETO融合蛋白的机制研究 刘旭玲 615
全面二孩政策前后早产儿发生情况及结局分析 朱丹丹 615
Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series Xu, Xiao-Wei 613
牙缺损伴牙颌畸形行正畸修复联合治疗的临床研究 潘孝义 612
原发性开角型青光眼黏小管成形术后早期短暂性高眼压的发生率及危险因素分析(英文) 徐丽娟 612
An investigation into Chinese university EFL teachers' professional identity tensions from a dissonance theory perspective Wang, Li 612
The relationship between phubbing and the depression of primary and secondary school teachers: A moderated mediation model of rumination and job burnout Liu, Jing 610
The role of external signal regulated kinase and transforming growth factor β1 in asthma airway remodeling and regulation of glucocorticoids Xiao-jun Guan 609
一种聚乳酸/纳米羟基磷灰石复合微球包裹的硫酸庆大霉素及其制备方法 陈浩 605
Tumor protein P63 Regulated 1 contributes to inflammation and cell proliferation of cystitis glandularis through regulating the NF-kB/cyclooxygenase-2/ prostaglandin E2 axis Hong, Tao 603
Endoplasmic Reticulum Stress and Atherosclerosis Zhou, Huiping 602
A synthetic microbial consortium protects against obesity by regulating vitamin B6 metabolism Chen, Xiuzhao 602
Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes Xue, Angli 601
New Perspectives on Dry Eye Definition and Diagnosis: A Consensus Report by the Asia Dry Eye Society Tsubota, Kazuo 601