Diagnostic value of endobronchial ultrasound elastography for differentiating benign and malignant hilar and mediastinal lymph nodes: a systematic review and meta-analysis

doi:10.11152/mu-2871

科研成果详情

题名	Diagnostic value of endobronchial ultrasound elastography for differentiating benign and malignant hilar and mediastinal lymph nodes: a systematic review and meta-analysis
作者	Wu, Jiangfeng; Sun, Yue; Wang, Yunlai; Ge, Lijing; Jin, Yun; Wang, Zhengping
发表期刊	MEDICAL ULTRASONOGRAPHY 影响因子和分区
语种	英语
原始文献类型	Review
关键词	endobronchial ultrasound elastography lymph nodes diagnosis meta-analysis
其他关键词	ASPIRATION EBUS-TBNA ; STRAIN ELASTOGRAPHY ; ELASTIC-MODULI ; TEST ACCURACY ; TISSUES ; UPDATE ; BREAST
摘要	Aims: In the present study, a meta-analysis was performed to evaluate the diagnostic value of endobronchial ultrasound (EBUS) elastography for differentiating benign and malignant hilar and mediastinal lymph nodes (LNs). Material and methods: A comprehensive literature search was carried out through PubMed, Embase, and Cochrane Library. Two authors screened the papers and extracted the data independently and any discrepancies were resolved by discussion. The methodolog-ical quality of each included study was assessed by the Quality Assessment of Diagnostic Accuracy Studies 2 tool. Sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, and area under the curve were calculated to evaluate the value of EBUS elastography for hilar and mediastinal LNs. Results: Seventeen studies with the number of 2307 LNs were included. There was significant heterogeneity across the included studies. The pooled sensitivity, specificity, positive likelihood ratio, negative likelihood ratio and diagnostic odds ratio for the diagnosis of hilar and mediastinal LNs by EBUS elastography were 0.90 (95% confidence interval [CI], 0.84-0.94), 0.78 (95% CI, 0.74-0.81), 4.1 (95% CI, 3.4-4.9), 0.12 (95% CI, 0.07-0.21) and 33 (95% CI, 17-64), respectively. Furthermore, area under the curve was calculated to be 0.86 (95% CI, 0.82-0.88). Conclusion: EBUS elastography is a valuable technology in the differentiation of benign and malignant hilar and mediastinal LNs and could provide supplementary diagnostic information during endobronchial ultrasound-guided transbronchial needle aspiration. The combination of EBUS elastography and B-mode EBUS could improve the diagnostic accuracy for hilar and mediastinal LNs.
出版者	SOC ROMANA ULTRASONOGRAFE MEDICINA BIOLOGIE-SRUMB
出版地	CLUJ-NAPOCA
ISSN	1844-4172
EISSN	2066-8643
卷号	24 期号:1 页码:85-94
DOI	10.11152/mu-2871
页数	10
WOS类目	Acoustics ; Radiology, Nuclear Medicine & Medical Imaging
WOS研究方向	Acoustics ; Radiology, Nuclear Medicine & Medical Imaging
WOS记录号	WOS:000757506800013
收录类别	SCIE ; SCOPUS ; PUBMED
发表日期	2022
URL	查看原文
Pubmed记录号	33793697
Scopus记录号	2-s2.0-85124794016
引用统计	被引频次：2[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/14607
专题	其他_附属东阳医院（东阳市人民医院）
通讯作者	Wu, Jiangfeng
作者单位	Wenzhou Med Univ, Dept Ultrasound, Affiliated Dongyang Hosp, 60 Wuning West Rd, Dongyang 322100, Zhejiang, Peoples R China
第一作者单位	附属东阳医院（东阳市人民医院）
通讯作者单位	附属东阳医院（东阳市人民医院）
第一作者的第一单位	附属东阳医院（东阳市人民医院）
推荐引用方式 GB/T 7714	Wu, Jiangfeng,Sun, Yue,Wang, Yunlai,et al. Diagnostic value of endobronchial ultrasound elastography for differentiating benign and malignant hilar and mediastinal lymph nodes: a systematic review and meta-analysis[J]. MEDICAL ULTRASONOGRAPHY,2022,24(1):85-94.
APA	Wu, Jiangfeng, Sun, Yue, Wang, Yunlai, Ge, Lijing, Jin, Yun, & Wang, Zhengping. (2022). Diagnostic value of endobronchial ultrasound elastography for differentiating benign and malignant hilar and mediastinal lymph nodes: a systematic review and meta-analysis. MEDICAL ULTRASONOGRAPHY, 24(1), 85-94.
MLA	Wu, Jiangfeng,et al."Diagnostic value of endobronchial ultrasound elastography for differentiating benign and malignant hilar and mediastinal lymph nodes: a systematic review and meta-analysis".MEDICAL ULTRASONOGRAPHY 24.1(2022):85-94.