题名 | Connecting the Dots: The Cerebral Lymphatic System as a Bridge Between the Central Nervous System and Peripheral System in Health and Disease |
作者 | Zhao, Hongxiang1; Sun, Meiyan1; Zhang, Yue; Kong, Wenwen3; Fan, Lulu3; Wang, Kaifang3; Xu, Qing5; Chen, Baiyan3; Dong, Jianxin3; Shi, Yanan3; Wang, Zhengyan3; Wang, ShiQi3; Zhuang, Xiaoli6; Li, Qi7; Lin, Feihong8; Yao, Xinyu9; Zhang, WenBo10; Kong, Chang11; Zhang, Rui2; Feng, Dayun4; Zhao, Xiaoyong1,2
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发表日期 | 2023-05-20 |
发表期刊 | AGING AND DISEASE 影响因子和分区 |
语种 | 英语 |
原始文献类型 | Review ; Early Access |
关键词 | Cerebral lymphatic system peripheral system meningeal lymphatic vessels glymphatic system liver kidney gastrointestinal tract |
其他关键词 | CHRONIC KIDNEY-DISEASE ; VIRCHOW-ROBIN SPACES ; BLOOD-BRAIN-BARRIER ; SQUAMOUS-CELL CARCINOMA ; FECAL MICROBIOTA TRANSPLANTATION ; ANTIBIOTIC-INDUCED PERTURBATIONS ; DIALYSIS DISEQUILIBRIUM SYNDROME ; ENLARGED PERIVASCULAR SPACES ; RECEPTOR-RELATED PROTEIN-1 ; GUT-MICROBIOTA |
摘要 | As a recently discovered waste removal system in the brain, cerebral lymphatic system is thought to play an important role in regulating the homeostasis of the central nervous system. Currently, more and more attention is being focused on cerebral lymphatic system. Further understanding of the structural and functional characteristics of cerebral lymphatic system is essential to better understand the pathogenesis of diseases and to explore therapeutic approaches. In this review, we summarize the structural components and functional characteristics of cerebral lymphatic system. More importantly, it is closely associated with peripheral system diseases in the liver, gastrointestinal tract, kidney, and other sites. However, there is still a gap in the study of cerebral lymphatic system, but we suggest that it acts as a bridge between the central nervous system and the peripheral system and as a key intermediary in their interaction. |
资助项目 | Natural Science Foundation of Shandong Province [ZR2016HP06]; Shandong Medical and Health Science and Technology Development Project [2019WS605, 202104110334]; Weifang Medical University Students Innovation and Entrepreneurship Training Program Project [X2021517, X2021516, X2021514]; Weifang Science and Technology Development Project [2021YX028] |
出版者 | INT SOC AGING & DISEASE |
ISSN | 2152-5250 |
卷号 | 15期号:1页码:115-152 |
DOI | 10.14336/AD.2023.0516 |
页数 | 38 |
WOS类目 | Geriatrics & Gerontology |
WOS研究方向 | Geriatrics & Gerontology |
WOS记录号 | WOS:000995889600001 |
收录类别 | SCIE ; PUBMED ; SCOPUS |
URL | 查看原文 |
PubMed ID | 37307828 |
SCOPUSEID | 2-s2.0-85179705965 |
通讯作者地址 | [Zhao, Xiaoyong]Shandong First Medical University,Shandong Academy of Medical Sciences,Shandong,Jinan,China |
Scopus学科分类 | Pathology and Forensic Medicine;Geriatrics and Gerontology;Neurology (clinical);Cell Biology |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | https://kms.wmu.edu.cn/handle/3ETUA0LF/181022 |
专题 | 附属第一医院 |
通讯作者 | Zhao, Xiaoyong |
作者单位 | 1.Shandong Cancer Hospital and Institute,Shandong First Medical University,Shandong Academy of Medical Sciences,Shandong,Jinan,China; 2.Department of Anesthesiology,Affiliated Hospital of Weifang Medical University,Weifang,China; 3.Shandong Provincial Medicine,Health Key Laboratory of Clinical Anesthesia,School of Anesthesiology,Weifang Medical University,Weifang,China; 4.Department of neurosurgery,Tangdu hospital,Fourth Military Medical University,Xi'an,China; 5.Department of Anesthesiology,Affiliated Hangzhou First People's Hospital,Zhejiang University School of Medicine,Hangzhou,China; 6.Department of Anesthesiology,Beijing Anzhen Hospital,Capital Medical University,Beijing,China; 7.Department of Anesthesiology,Ninth People's Hospital,Shanghai Jiaotong University School of Medicine,Shanghai,China; 8.Department of Anesthesiology,Shanghai Pulmonary Hospital,School of Medicine,Tongji University,Shanghai,China; 9.Department of Anesthesiology,The First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China; 10.Department of Neurosurgery,The Children’s Hospital of Zhejiang University School of Medicine,National Clinical Research Center for Child Health,Hangzhou,China; 11.Department of Anesthesiology and Critical Care Medicine,Tianjin Nankai Hospital,Tianjin Medical University,Tianjin,China |
推荐引用方式 GB/T 7714 | Zhao, Hongxiang,Sun, Meiyan,Zhang, Yue,et al. Connecting the Dots: The Cerebral Lymphatic System as a Bridge Between the Central Nervous System and Peripheral System in Health and Disease[J]. AGING AND DISEASE,2023,15(1):115-152. |
APA | Zhao, Hongxiang., Sun, Meiyan., Zhang, Yue., Kong, Wenwen., Fan, Lulu., ... & Zhao, Xiaoyong. (2023). Connecting the Dots: The Cerebral Lymphatic System as a Bridge Between the Central Nervous System and Peripheral System in Health and Disease. AGING AND DISEASE, 15(1), 115-152. |
MLA | Zhao, Hongxiang,et al."Connecting the Dots: The Cerebral Lymphatic System as a Bridge Between the Central Nervous System and Peripheral System in Health and Disease".AGING AND DISEASE 15.1(2023):115-152. |
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