Connecting the Dots: The Cerebral Lymphatic System as a Bridge Between the Central Nervous System and Peripheral System in Health and Disease

doi:10.14336/AD.2023.0516

科研成果详情

题名	Connecting the Dots: The Cerebral Lymphatic System as a Bridge Between the Central Nervous System and Peripheral System in Health and Disease
作者	Zhao, Hongxiang 1; Sun, Meiyan 1; Zhang, Yue ; Kong, Wenwen 3; Fan, Lulu 3; Wang, Kaifang 3; Xu, Qing 5; Chen, Baiyan 3; Dong, Jianxin 3; Shi, Yanan 3; Wang, Zhengyan 3; Wang, ShiQi 3; Zhuang, Xiaoli 6; Li, Qi 7; Lin, Feihong 8; Yao, Xinyu 9; Zhang, WenBo 10; Kong, Chang 11; Zhang, Rui 2; Feng, Dayun 4; Zhao, Xiaoyong 1,2
发表日期	2023-05-20
发表期刊	AGING AND DISEASE 影响因子和分区
语种	英语
原始文献类型	Review ; Early Access
关键词	Cerebral lymphatic system peripheral system meningeal lymphatic vessels glymphatic system liver kidney gastrointestinal tract
其他关键词	CHRONIC KIDNEY-DISEASE ; VIRCHOW-ROBIN SPACES ; BLOOD-BRAIN-BARRIER ; SQUAMOUS-CELL CARCINOMA ; FECAL MICROBIOTA TRANSPLANTATION ; ANTIBIOTIC-INDUCED PERTURBATIONS ; DIALYSIS DISEQUILIBRIUM SYNDROME ; ENLARGED PERIVASCULAR SPACES ; RECEPTOR-RELATED PROTEIN-1 ; GUT-MICROBIOTA
摘要	As a recently discovered waste removal system in the brain, cerebral lymphatic system is thought to play an important role in regulating the homeostasis of the central nervous system. Currently, more and more attention is being focused on cerebral lymphatic system. Further understanding of the structural and functional characteristics of cerebral lymphatic system is essential to better understand the pathogenesis of diseases and to explore therapeutic approaches. In this review, we summarize the structural components and functional characteristics of cerebral lymphatic system. More importantly, it is closely associated with peripheral system diseases in the liver, gastrointestinal tract, kidney, and other sites. However, there is still a gap in the study of cerebral lymphatic system, but we suggest that it acts as a bridge between the central nervous system and the peripheral system and as a key intermediary in their interaction.
资助项目	Natural Science Foundation of Shandong Province [ZR2016HP06]; Shandong Medical and Health Science and Technology Development Project [2019WS605, 202104110334]; Weifang Medical University Students Innovation and Entrepreneurship Training Program Project [X2021517, X2021516, X2021514]; Weifang Science and Technology Development Project [2021YX028]
出版者	INT SOC AGING & DISEASE
ISSN	2152-5250
卷号	15 期号:1 页码:115-152
DOI	10.14336/AD.2023.0516
页数	38
WOS类目	Geriatrics & Gerontology
WOS研究方向	Geriatrics & Gerontology
WOS记录号	WOS:000995889600001
收录类别	SCIE ; PUBMED ; SCOPUS
URL	查看原文
PubMed ID	37307828
SCOPUSEID	2-s2.0-85179705965
通讯作者地址	[Zhao, Xiaoyong]Shandong First Medical University,Shandong Academy of Medical Sciences,Shandong,Jinan,China
Scopus学科分类	Pathology and Forensic Medicine;Geriatrics and Gerontology;Neurology (clinical);Cell Biology
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/181022
专题	第一临床医学院（信息与工程学院）、附属第一医院_麻醉科附属第一医院_麻醉科
通讯作者	Zhao, Xiaoyong
作者单位	1.Shandong Cancer Hospital and Institute,Shandong First Medical University,Shandong Academy of Medical Sciences,Shandong,Jinan,China; 2.Department of Anesthesiology,Affiliated Hospital of Weifang Medical University,Weifang,China; 3.Shandong Provincial Medicine,Health Key Laboratory of Clinical Anesthesia,School of Anesthesiology,Weifang Medical University,Weifang,China; 4.Department of neurosurgery,Tangdu hospital,Fourth Military Medical University,Xi'an,China; 5.Department of Anesthesiology,Affiliated Hangzhou First People's Hospital,Zhejiang University School of Medicine,Hangzhou,China; 6.Department of Anesthesiology,Beijing Anzhen Hospital,Capital Medical University,Beijing,China; 7.Department of Anesthesiology,Ninth People's Hospital,Shanghai Jiaotong University School of Medicine,Shanghai,China; 8.Department of Anesthesiology,Shanghai Pulmonary Hospital,School of Medicine,Tongji University,Shanghai,China; 9.Department of Anesthesiology,The First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China; 10.Department of Neurosurgery,The Children’s Hospital of Zhejiang University School of Medicine,National Clinical Research Center for Child Health,Hangzhou,China; 11.Department of Anesthesiology and Critical Care Medicine,Tianjin Nankai Hospital,Tianjin Medical University,Tianjin,China
推荐引用方式 GB/T 7714	Zhao, Hongxiang,Sun, Meiyan,Zhang, Yue,et al. Connecting the Dots: The Cerebral Lymphatic System as a Bridge Between the Central Nervous System and Peripheral System in Health and Disease[J]. AGING AND DISEASE,2023,15(1):115-152.
APA	Zhao, Hongxiang., Sun, Meiyan., Zhang, Yue., Kong, Wenwen., Fan, Lulu., ... & Zhao, Xiaoyong. (2023). Connecting the Dots: The Cerebral Lymphatic System as a Bridge Between the Central Nervous System and Peripheral System in Health and Disease. AGING AND DISEASE, 15(1), 115-152.
MLA	Zhao, Hongxiang,et al."Connecting the Dots: The Cerebral Lymphatic System as a Bridge Between the Central Nervous System and Peripheral System in Health and Disease".AGING AND DISEASE 15.1(2023):115-152.