Three-dimensional (3D) printed scaffold and material selection for bone repair

doi:10.1016/j.actbio.2018.11.039

科研成果详情

题名	Three-dimensional (3D) printed scaffold and material selection for bone repair
作者	Zhang, Lei1; Yang, Guojing 1; Johnson, Blake N.2; Jia, Xiaofeng 3,4,5,6,7
发表期刊	ACTA BIOMATERIALIA 影响因子和分区
语种	英语
原始文献类型	Review
关键词	3D printing Bone tissue engineering Bone defect Porous scaffold Biomaterials
其他关键词	BETA-TRICALCIUM PHOSPHATE ; MESENCHYMAL STEM-CELLS ; BIOACTIVE GLASS SCAFFOLDS ; PROMOTES CHONDROGENIC DIFFERENTIATION ; POLY(PROPYLENE FUMARATE) SCAFFOLDS ; POROUS HYDROXYAPATITE SCAFFOLDS ; EPSILON-CAPROLACTONE SCAFFOLDS ; POLY(LACTIC ACID) SCAFFOLDS ; POLY-LACTIC-ACID ; MECHANICAL-PROPERTIES
摘要	Critical-sized bone defect repair remains a substantial challenge in clinical settings and requires bone grafts or bone substitute materials. However, existing biomaterials often do not meet the clinical requirements of structural support, osteoinductive property, and controllable biodegradability. To treat large-scale bone defects, the development of three-dimensional (3D) porous scaffolds has received considerable focus within bone engineering. A variety of biomaterials and manufacturing methods, including 3D printing, have emerged to fabricate patient-specific bioactive scaffolds that possess controlled micro-architectures for bridging bone defects in complex configurations. During the last decade, with the development of the 3D printing industry, a large number of tissue-engineered scaffolds have been created for preclinical and clinical applications using novel materials and innovative technologies. Thus, this review provides a brief overview of current progress in existing biomaterials and tissue engineering scaffolds prepared by 3D printing technologies, with an emphasis on the material selection, scaffold design optimization, and their preclinical and clinical applications in the repair of critical-sized bone defects. Furthermore, it will elaborate on the current limitations and potential future prospects of 3D printing technology. Statement of Significance 3D printing has emerged as a critical fabrication process for bone engineering due to its ability to control bulk geometry and internal structure of tissue scaffolds. The advancement of bioprinting methods and compatible ink materials for bone engineering have been a major focus to develop optimal 3D scaffolds for bone defect repair. Achieving a successful balance of cellular function, cellular viability, and mechanical integrity under load-bearing conditions is critical. Hybridization of natural and synthetic polymerbased materials is a promising approach to create novel tissue engineered scaffolds that combines the advantages of both materials and meets various requirements, including biological activity, mechanical strength, easy fabrication and controllable degradation. 3D printing is linked to the future of bone grafts to create on-demand patient-specific scaffolds. (C) 2018 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
资助项目	Maryland Stem Cell Research Fund, USA [2018-MSCRFD-4271]
出版者	ELSEVIER SCI LTD
出版地	OXFORD
ISSN	1742-7061
EISSN	1878-7568
卷号	84 页码:16-33
DOI	10.1016/j.actbio.2018.11.039
WOS类目	Engineering, Biomedical ; Materials Science, Biomaterials
WOS研究方向	Engineering ; Materials Science
WOS记录号	WOS:000456902700002
收录类别	SCIE ; PUBMED ; EI ; SCOPUS
发表日期	2019-01-15
EI入藏号	20215111347835
URL	查看原文
Pubmed记录号	30481607
Scopus记录号	2-s2.0-85058509279
ESI高被引论文	2020-03 ; 2020-05 ; 2020-09 ; 2020-11 ; 2021-01 ; 2021-03 ; 2021-05 ; 2021-07 ; 2021-09 ; 2021-11 ; 2022-01 ; 2022-03 ; 2022-05 ; 2022-07 ; 2022-09 ; 2022-11 ; 2023-01 ; 2023-03 ; 2023-05 ; 2023-07 ; 2023-09 ; 2023-11 ; 2024-01 ; 2024-03 ; 2024-05
引用统计	被引频次：293[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/10692
专题	其他_附属第三医院（瑞安市人民医院）
通讯作者	Jia, Xiaofeng
作者单位	1.Wenzhou Med Univ, Affiliated Hosp 3, Dept Orthopaed, Wenzhou 325200, Zhejiang, Peoples R China; 2.Virginia Tech, Dept Ind & Syst Engn, Blacksburg, VA 24061 USA; 3.Univ Maryland, Sch Med, Dept Neurosurg, Baltimore, MD 21201 USA; 4.Univ Maryland, Sch Med, Dept Orthoped, Baltimore, MD 21201 USA; 5.Univ Maryland, Sch Med, Dept Anat & Neurobiol, Baltimore, MD 21201 USA; 6.Johns Hopkins Univ, Sch Med, Dept Biomed Engn, Baltimore, MD 21205 USA; 7.Johns Hopkins Univ, Sch Med, Dept Anesthesiol & Crit Care Med, Baltimore, MD 21205 USA
第一作者单位	附属第三医院（瑞安市人民医院）; 温州市第三临床学院（温州市人民医院）
第一作者的第一单位	附属第三医院（瑞安市人民医院）
推荐引用方式 GB/T 7714	Zhang, Lei,Yang, Guojing,Johnson, Blake N.,et al. Three-dimensional (3D) printed scaffold and material selection for bone repair[J]. ACTA BIOMATERIALIA,2019,84:16-33.
APA	Zhang, Lei, Yang, Guojing, Johnson, Blake N., & Jia, Xiaofeng. (2019). Three-dimensional (3D) printed scaffold and material selection for bone repair. ACTA BIOMATERIALIA, 84, 16-33.
MLA	Zhang, Lei,et al."Three-dimensional (3D) printed scaffold and material selection for bone repair".ACTA BIOMATERIALIA 84(2019):16-33.