Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series

doi:10.1136/bmj.m606

科研成果详情

题名	Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series
作者	Xu, Xiao-Wei 1; Wu, Xiao-Xin 1; Jiang, Xian-Gao 2; Xu, Kai-Jin 1; Ying, Ling-Jun 3; Ma, Chun-Lian 4; Li, Shi-Bo5; Wang, Hua-Ying 6; Zhang, Sheng 7; Gao, Hai-Nv 8; Sheng, Ji-Fang 1; Cai, Hong-Liu 1; Qiu, Yun-Qing 1; Li, Lan-Juan 1
发表日期	2020-02-19
发表期刊	BMJ-BRITISH MEDICAL JOURNAL 影响因子和分区
语种	英语
原始文献类型	Article
摘要	OBJECTIVE To study the clinical characteristics of patients in Zhejiang province, China, infected with the 2019 severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) responsible for coronavirus disease 2019 (covid-2019). DESIGN Retrospective case series. SETTING Seven hospitals in Zhejiang province, China. PARTICIPANTS 62 patients admitted to hospital with laboratory confirmed SARS-Cov-2 infection. Data were collected from 10 January 2020 to 26 January 2020. MAIN OUTCOME MEASURES Clinical data, collected using a standardised case report form, such as temperature, history of exposure, incubation period. If information was not clear, the working group in Hangzhou contacted the doctor responsible for treating the patient for clarification. RESULTS Of the 62 patients studied (median age 41 years), only one was admitted to an intensive care unit, and no patients died during the study. According to research, none of the infected patients in Zhejiang province were ever exposed to the Huanan seafood market, the original source of the virus; all studied cases were infected by human to human transmission. The most common symptoms at onset of illness were fever in 48 (77%) patients, cough in 50 (81%), expectoration in 35 (56%), headache in 21 (34%), myalgia or fatigue in 32 (52%), diarrhoea in 3 (8%), and haemoptysis in 2 (3%). Only two patients (3%) developed shortness of breath on admission. The median time from exposure to onset of illness was 4 days (interquartile range 3-5 days), and from onset of symptoms to first hospital admission was 2 (1-4) days. CONCLUSION As of early February 2020, compared with patients initially infected with SARS-Cov-2 in Wuhan, the symptoms of patients in Zhejiang province are relatively mild.
出版者	BMJ PUBLISHING GROUP
出版地	LONDON
ISSN	0959-535X
EISSN	1756-1833
卷号	368 页码:m606.
DOI	10.1136/bmj.m606
页数	7
WOS类目	Medicine, General & Internal
WOS研究方向	General & Internal Medicine
WOS记录号	WOS:000515235300008
收录类别	SCIE ; PUBMED ; SCOPUS
URL	查看原文
PubMed ID	32075786
PMC记录号	PMC7224340
SCOPUSEID	2-s2.0-85079760608
ESI热点论文	2020-09 ; 2020-11 ; 2021-01 ; 2021-03 ; 2021-05 ; 2021-07 ; 2021-09 ; 2021-11 ; 2022-01 ; 2022-03
ESI高被引论文	2020-09 ; 2020-11 ; 2021-01 ; 2021-03 ; 2021-05 ; 2021-07 ; 2021-11 ; 2022-01 ; 2022-03 ; 2022-07 ; 2022-09 ; 2022-11 ; 2023-01 ; 2023-03 ; 2023-05 ; 2023-07 ; 2023-09 ; 2023-11 ; 2024-01 ; 2024-03 ; 2024-05 ; 2024-07 ; 2024-09 ; 2024-11
通讯作者地址	[Li, Lan-Juan]State Key Laboratory for Diagnosis and Treatment of Infectious Diseases,National Clinical Research Centre for Infectious Diseases,Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases,First Affiliated Hospital,College of Medicine,Zhejiang University,Hangzhou, Zhejiang Province,310003,China
Scopus学科分类	Medicine (all)
TOP期刊	TOP期刊
引用统计	被引频次：1720[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/19753
专题	其他_附属舟山医院（舟山医院）
通讯作者	Li, Lan-Juan
作者单位	1.State Key Laboratory for Diagnosis and Treatment of Infectious Diseases,National Clinical Research Centre for Infectious Diseases,Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases,First Affiliated Hospital,College of Medicine,Zhejiang University,Hangzhou, Zhejiang Province,310003,China; 2.Department of Infectious Disease,Wenzhou Central Hospital,Wenzhou, Zhejiang Province,China; 3.Department of Infectious Disease,Taizhou Enze Medical Centre (Group),Enze Hospital,Taizhou, Zhejiang Province,China; 4.Department of Infectious Disease,First People's Hospital of Wenling,Wenling, Zhejiang Province,China; 5.Department of Infectious Disease,Affiliated Zhoushan Hospital,Wenzhou Medical University,Zhoushan, Zhejiang Province,China; 6.Department of Respiratory and Critical Care Medicine,Yinzhou People's Hospital,Affiliated Yinzhou Hospital,College of Medicine,Ningbo University,Ningbo City, Zhejiang Province,China; 7.Department of Infectious Disease,Taizhou Hospital,Taizhou, Zhejiang Province,China; 8.Department of Infectious Disease,ShuLan Hospital Affiliated to Zhejiang Shuren University Shulan International Medical College,Hangzhou, Zhejiang Province,China
推荐引用方式 GB/T 7714	Xu, Xiao-Wei,Wu, Xiao-Xin,Jiang, Xian-Gao,et al. Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series[J]. BMJ-BRITISH MEDICAL JOURNAL,2020,368:m606..
APA	Xu, Xiao-Wei., Wu, Xiao-Xin., Jiang, Xian-Gao., Xu, Kai-Jin., Ying, Ling-Jun., ... & Li, Lan-Juan. (2020). Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series. BMJ-BRITISH MEDICAL JOURNAL, 368, m606..
MLA	Xu, Xiao-Wei,et al."Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series".BMJ-BRITISH MEDICAL JOURNAL 368(2020):m606..