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生物有机与药物化学研究中心
浏览/检索结果:共380条,第1-10条
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Blockage of MyD88 in cardiomyocytes alleviates cardiac inflammation and cardiomyopathy in experimental diabetic mice.
期刊论文
Wenzhou Medical University First Affiliated Hospital, Biochemical pharmacology, 2022, 卷号: 206, 页码: 115292
作者:
Luo, Wu
;
Wu, Gaojun
; Chen, Xiaojun; Zhang, Qiuyan;
Zou, Chunpeng
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/11/08
Cardiomyocytes
Diabetic cardiomyopathy
Fibrosis
Inflammation
MyD88
Blockage of DCLK1 in cardiomyocytes suppresses myocardial inflammation and alleviates diabetic cardiomyopathy in streptozotocin-induced diabetic mice
期刊论文
Wenzhou Medical University First Affiliated Hospital, Biochimica et biophysica acta. Molecular basis of disease, 2024, 卷号: 1870, 期号: 1
作者:
Ji, Lijun
;
Yang, Xiaojing
; Jin, Yiyi; Li, Li;
Yang, Bin
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2023/10/18
Cardiomyocyte
DCLK1
Diabetic cardiomyopathy
Inflammation
NF-κB
Tabersonine alleviates obesity-induced cardiomyopathy by binding to Transforming growth factor activated kinase 1 (TAK1) and inhibiting TAK1-mediated inflammation.
期刊论文
Wenzhou Medical University First Affiliated Hospital, Phytotherapy research : PTR, 2023, 卷号: 37, 期号: 3, 页码: 860-871
作者:
Chen, Yanghao
;
Lin, Wante
;
Chen, Pan
;
Ye, Bozhi
;
Luo, Wu
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/12/19
TAK1
Tabersonine
inflammation
obesity-induced cardiomyopathy
Curcumin Analogue CA15 Exhibits Anticancer Effects on HEp-2 Cells via Targeting NF-kappa B
期刊论文
Wenzhou Medical University School of Pharmaceutical Sciences(Analytical and Testing Center), BIOMED RESEARCH INTERNATIONAL, 2017, 卷号: 2017, 页码: 4751260
作者: Chen, Jian; Zhang, Linlin; Shu, Yilai; Chen, Liping; Zhu, Min
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2022/03/27
e-Graphene: A Computational Platform for the Prediction of Graphene-Based Drug Delivery System by Quantum Genetic Algorithm and Cascade Protocol
期刊论文
Wenzhou Medical University School of Pharmaceutical Sciences(Analytical and Testing Center), FRONTIERS IN CHEMISTRY, 2021, 卷号: 9, 页码: 664355
作者:
Zheng, Suqing
; Xiong, Jun;
Wang, Lei
; Zhai, Dong; Xu, Yong
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2022/03/26
graphene
graphene-based drug delivery system
GDDS
prediction
quantum genetic algorithm
cascade protocol
QGA
Deubiquitinase OTUD6a drives cardiac inflammation and hypertrophy by deubiquitination of STING
期刊论文
Wenzhou Medical University School of Pharmaceutical Sciences(Analytical and Testing Center), Biochimica et biophysica acta. Molecular basis of disease, 2024, 卷号: 1870, 期号: 4
作者:
Fang, Zimin
; Han, Jibo;
Lin, Liming
;
Ye, Bozhi
; Qu, Xuefeng
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/02/27
Cardiac hypertrophy
Deubiquitination enzyme
Inflammation
OTU domain-containing protein 6a
Stimulator of interferon genes
Prediction of Hemolytic Toxicity for Saponins by Machine-Learning Methods
期刊论文
Wenzhou Medical University School of Pharmaceutical Sciences(Analytical and Testing Center), CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 6, 页码: 1014-1026
作者:
Zheng, Suqing
; Wang, Yibing; Liu, Hongmei; Chang, Wenping; Xu, Yong
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2022/03/26
11 beta- Hydroxysteroid Dehydrogenase Type 1(11 beta-HSD1) mediates insulin resistance through JNK activation in adipocytes
期刊论文
Wenzhou Medical University School of Pharmaceutical Sciences(Analytical and Testing Center), SCIENTIFIC REPORTS, 2016, 卷号: 6, 页码: 37160
作者:
Peng, Kesong
; Pan, Yong; Li, Jieli; Khan, Zia; Fan, Mendi
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2022/03/27
Licochalcone A Inhibits the Proliferation of Human Lung Cancer Cell Lines A549 and H460 by Inducing G2/M Cell Cycle Arrest and ER Stress
期刊论文
Wenzhou Medical University School of Pharmaceutical Sciences(Analytical and Testing Center), INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017, 卷号: 18, 期号: 8, 页码: 1761
作者:
Qiu, Chenyu
;
Zhang, Tingting
; Zhang, Wenxin; Zhou, Lina; Yu, Bin
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2022/03/26
Licochalcone A
cell cycle arrest
ER stress
lung cancer
apoptosis
Deubiquitinase JOSD2 improves calcium handling and attenuates cardiac hypertrophy and dysfunction by stabilizing SERCA2a in cardiomyocytes
期刊论文
Wenzhou Medical University School of Pharmaceutical Sciences(Analytical and Testing Center), Nature Cardiovascular Research, 2023, 卷号: 2, 期号: 8, 页码: 764-777
作者:
Han, Jibo
;
Fang, Zimin
; Han, Bingjiang;
Ye, Bozhi
;
Lin, Wante
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浏览/下载:163/60
  |  
提交时间:2023/12/07