Effects of three root-end filling materials on human periodontal ligament cells in an in vitro wound model

科研成果详情

题名	Effects of three root-end filling materials on human periodontal ligament cells in an in vitro wound model
作者	Ling Li; Qian Wang
发表日期	2011-02-01
发表期刊	Shanghai kou qiang yi xue = Shanghai journal of stomatology 影响因子和分区
语种	英语
原始文献类型	Article
摘要	Purpose: To compare the effects of mineral trioxide aggregate (MTA), amalgam and intermediate restorative material (IRM) on human periodontal ligament cells (HPDLC) using an in vitro wound healing model. Methods: Wound was created by making a 3mm in width incision in the cell monolayer across the length of tissue culture plate, then the cell monolayer was treated with media containing MTA, IRM, and amalgam extracts, respectively. Medium supplemented with fetal bovine serum (10%FBS) served as positive control, and that with 0.1% FBS as negative control. The cells were incubated for 2, 6 and 9 days, and at each time point, the levels of both proliferation and cellular wound filling were measured across the width of the wound. SPSS 11.5 software package was used for analyze. Results: There was little cellular repopulation of the wound on the day 2. On the day 6 and day 9, the order of response was MTA > amalgam > IRM (P < 0.05). For the cell proliferative activity, the order was MTA > amalgam approximately equal to IRM on the day 2. Conclusion: This study suggests that the degree of cytotoxic effect in ascending order is MTA, amalgam and IRM.
ISSN	1006-7248
卷号	20 期号:1 页码:41-5.
收录类别	PUBMED ; SCOPUS
URL	查看原文
Pubmed记录号	21451897
Scopus记录号	2-s2.0-84867126271
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/63442
专题	口腔医学院、附属口腔医院_儿童口腔
作者单位	Department of Pediatric Dentistry, School and Hospital of Stomatology, Wenzhou Medical College, Wenzhou 325027, Zhejiang Province, China. lealyne@163.com
第一作者单位	口腔医学院、附属口腔医院; 儿童口腔
第一作者的第一单位	口腔医学院、附属口腔医院
推荐引用方式 GB/T 7714	Ling Li,Qian Wang. Effects of three root-end filling materials on human periodontal ligament cells in an in vitro wound model[J]. Shanghai kou qiang yi xue = Shanghai journal of stomatology,2011,20(1):41-5..
APA	Ling Li, & Qian Wang. (2011). Effects of three root-end filling materials on human periodontal ligament cells in an in vitro wound model. Shanghai kou qiang yi xue = Shanghai journal of stomatology, 20(1), 41-5..
MLA	Ling Li,et al."Effects of three root-end filling materials on human periodontal ligament cells in an in vitro wound model".Shanghai kou qiang yi xue = Shanghai journal of stomatology 20.1(2011):41-5..

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