Association between polymorphisms of HIF-1alpha, eNOS genes and individual variation in response to hypoxia training

科研成果详情

题名	Association between polymorphisms of HIF-1alpha, eNOS genes and individual variation in response to hypoxia training
作者	Hai-Ping Liu; Yang Hu
发表日期	2006-11-01
发表期刊	Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 影响因子和分区
语种	英语
原始文献类型	Article
摘要	Aim: To investigated association between polymorphisms of HIF-1alpha, eNOS genes and individual variation in response to intermittent hypoxia training. Methods: 41 health subjects, completed 4 weeks hypoxia training program (hypoxia exposure 10 h each day and 3 times hypoxia training each week), to observed the relationship between C1772T polymorphism in exon 12 of HIF-1alpha gene and 27-base pair(bp) variable number of tandem repeat polymorphism (VNTR), 4b/a, in intron 4 of eNOS gene and physiological parameters, such as VO2(max), Hb, RBC and SpaO2. Results: The results showed that the change of VO2(max) was higher in carriers with CT genotype than those of CC genotype, and the changes of Hb and RBC indicated higher tendency in the subjects carrying the CT genotype. Same results were observed in the changes of SpaO2 during period of exercising under hypoxic condition. Conclusion: These findings suggested the possible associations between SNP/C1772T, VNTR/4ba and the individual variation in response to hypoxia training.
ISSN	1000-6834
卷号	22 期号:4 页码:434-8.
收录类别	PUBMED ; SCOPUS
URL	查看原文
PubMed ID	21155268
SCOPUSEID	2-s2.0-84928587120
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/63001
专题	体育科学部_运动人体科学系
作者单位	Department of Sports and Wenzhou Medical College, Wenzhou, 325035, China.
第一作者单位	运动人体科学系
第一作者的第一单位	运动人体科学系
推荐引用方式 GB/T 7714	Hai-Ping Liu,Yang Hu. Association between polymorphisms of HIF-1alpha, eNOS genes and individual variation in response to hypoxia training[J]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology,2006,22(4):434-8..
APA	Hai-Ping Liu, & Yang Hu. (2006). Association between polymorphisms of HIF-1alpha, eNOS genes and individual variation in response to hypoxia training. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 22(4), 434-8..
MLA	Hai-Ping Liu,et al."Association between polymorphisms of HIF-1alpha, eNOS genes and individual variation in response to hypoxia training".Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 22.4(2006):434-8..