A novel raiometric fluorescence probe based on silicon quantum dots and copper nanoclusters for visual assay of l-cysteine in milks

doi:10.1016/j.foodchem.2022.132155

科研成果详情

题名	A novel raiometric fluorescence probe based on silicon quantum dots and copper nanoclusters for visual assay of l-cysteine in milks
作者	Ma, Yange 1; Mei, He1; Li, Yanyan1; Zhou, Peipei1; Mao, Guangyun1; Wang, Huili 2; Wang, Xuedong1,2
发表期刊	Food chemistry 影响因子和分区
语种	英语
原始文献类型	Journal article (JA)
关键词	Glutathione-stabilized copper nanoclusters Ratiometric fluorescent probe Silicon quantum dots Visual assay l-Cysteine.
其他关键词	TURN-OFF-ON ; CARBON NANOPARTICLES ; SENSITIVE DETECTION ; GOLD NANOCLUSTERS ; ACID ; NANOHYBRIDS ; SYSTEMS ; IONS ; PH
摘要	l-cysteine (l-Cys) plays an important role in many physiological processes. The previously reported methodologies for l-Cys detection have many drawbacks, and thus the development of specific/sensitive approaches is crucial for its direct/quick assay in food matrices. Herein, silicon quantum dots (SiQDs) and glutathione-stabilized copper nanoclusters (CuNCs) were successfully synthesized and integrated as a ratiometric fluorescent probe for assay l-Cys assay in milks. The fluorescence of SiQDs was quenched by CuNCs through fluorescence resonance energy-transfer process. Upon addition of l-Cys, the 440-nm fluorescence of SiQDs changed insignificantly, while the 650-nm fluorescence of CuNCs decreased significantly. Ratiometric fluorescence signal was linear in the l-Cys concentration range of 0.25 μM to 2.5 mM with a detection limit of 75 nM and visual color changes from red to blue. The probe can realize rapid and portable detection without the participation of intermediate ions, and has good selectivity and accuracy for l-cysteine in milk samples.
资助项目	National Natural Science Foundation of China[SS202028];
出版者	Elsevier Ltd
出版地	OXFORD
ISSN	0308-8146
EISSN	1873-7072
卷号	379 页码:132155
DOI	10.1016/j.foodchem.2022.132155
页数	40
WOS类目	Chemistry, Applied ; Food Science & Technology ; Nutrition & Dietetics
WOS研究方向	Chemistry ; Food Science & Technology ; Nutrition & Dietetics
WOS记录号	WOS:000790189200006
收录类别	PUBMED ; EI ; SCOPUS ; SCIE
发表日期	2022-06-15
EI入藏号	20220411494448
EI主题词	Peptides
EI分类号	461.9 Biology ; 544.1 Copper ; 549.3 Nonferrous Metals and Alloys excluding Alkali and Alkaline Earth Metals ; 714.2 Semiconductor Devices and Integrated Circuits ; 741.1 Light/Optics ; 761 Nanotechnology ; 804.1 Organic Compounds ; 933 Solid State Physics ; 933.1 Crystalline Solids
URL	查看原文
Pubmed记录号	35065492
Scopus记录号	2-s2.0-85123033805
引用统计	被引频次：2[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/33332
专题	公共卫生与管理学院
通讯作者	Wang, Xuedong
作者单位	1.Wenzhou Med Univ, Coll Publ Hlth & Management, Wenzhou 325035, Peoples R China; 2.Suzhou Univ Sci & Technol, Sch Environm Sci & Engn, Suzhou 215009, Peoples R China
第一作者单位	公共卫生学院
通讯作者单位	公共卫生学院
第一作者的第一单位	公共卫生学院; 公共卫生学院
推荐引用方式 GB/T 7714	Ma, Yange,Mei, He,Li, Yanyan,et al. A novel raiometric fluorescence probe based on silicon quantum dots and copper nanoclusters for visual assay of l-cysteine in milks[J]. Food chemistry,2022,379:132155.
APA	Ma, Yange., Mei, He., Li, Yanyan., Zhou, Peipei., Mao, Guangyun., ... & Wang, Xuedong. (2022). A novel raiometric fluorescence probe based on silicon quantum dots and copper nanoclusters for visual assay of l-cysteine in milks. Food chemistry, 379, 132155.
MLA	Ma, Yange,et al."A novel raiometric fluorescence probe based on silicon quantum dots and copper nanoclusters for visual assay of l-cysteine in milks".Food chemistry 379(2022):132155.