Anti-golgi antibodies: Prevalence and disease association in Chinese population

doi:10.1016/j.cca.2019.06.027

科研成果详情

题名	Anti-golgi antibodies: Prevalence and disease association in Chinese population
作者	Ma, Lisha; Zeng, Aiping; Chen, Ying; Chen, Binxuan; Zhou, Renfang
发表日期	2019-09-01
发表期刊	Clinica chimica acta; international journal of clinical chemistry 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Anti-golgi antibodies (AGAs) Anti-nuclear antibodies (ANA) Autoimmune disease (AID) Indirect immunofluorescence (IIF).
摘要	Objective:Anti-golgi antibodies (AGAs) are rarely encountered and often considered in relation to autoimmune diseases in clinical practice. This research was performed for studying the prevalence and clinical significance of AGAs in Chinese population. Methods:We retrospectively reviewed 22,619 laboratory reports of AGAs detected by indirect immunofluorescence (IIF) were consecutively collected from the First People's Hospital of Wenling between June 2012 and June 2017. Eight patients with AGAs were followed up for relevant clinical and laboratory characteristics. Result:A total of 22,619 laboratory reports were collected. Of 19 patients with AGAs, 7 cases (all females) had autoimmune diseases (AID) and 12 cases (6 females and 6 males) had non-AID. High titer AGAs ranging from 1:1000 to 1:3200 were persistently present in AID patients, while low-titer AGAs ranging from 1:100 to 1:320 were transient in non-AID patients. Conclusion:This is the first study to assess the AGA positive rate and relevant clinical manifestations in a hospitalized Chinese population. AGAs were rare and occurred in a variety of diseases. They were persistently strongly positive in AID, whereas low-titered and transient in non-AID.
出版者	Elsevier B.V.
ISSN	0009-8981
EISSN	1873-3492
卷号	496 页码:121-124.
DOI	10.1016/j.cca.2019.06.027
收录类别	PUBMED ; SCOPUS
URL	查看原文
PubMed ID	31278896
SCOPUSEID	2-s2.0-85068477921
通讯作者地址	[Zhou, Renfang]Department of Clinical Laboratory,the First People's Hospital of Wenling,Affiliated Wenzhou Medical University,Taizhou,China
Scopus学科分类	Biochemistry;Clinical Biochemistry;Biochemistry (medical)
引用统计	被引频次：2[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/33274
专题	温州医科大学
通讯作者	Zhou, Renfang
作者单位	Department of Clinical Laboratory,the First People's Hospital of Wenling,Affiliated Wenzhou Medical University,Taizhou,China
推荐引用方式 GB/T 7714	Ma, Lisha,Zeng, Aiping,Chen, Ying,et al. Anti-golgi antibodies: Prevalence and disease association in Chinese population[J]. Clinica chimica acta; international journal of clinical chemistry,2019,496:121-124..
APA	Ma, Lisha, Zeng, Aiping, Chen, Ying, Chen, Binxuan, & Zhou, Renfang. (2019). Anti-golgi antibodies: Prevalence and disease association in Chinese population. Clinica chimica acta; international journal of clinical chemistry, 496, 121-124..
MLA	Ma, Lisha,et al."Anti-golgi antibodies: Prevalence and disease association in Chinese population".Clinica chimica acta; international journal of clinical chemistry 496(2019):121-124..