Nonpharmacological interventions for relapse prevention in unipolar depression: A network meta-analysis

doi:10.1016/j.jad.2021.01.025

科研成果详情

题名	Nonpharmacological interventions for relapse prevention in unipolar depression: A network meta-analysis
作者	Zhou, Dongdong 1; Zhou, Xiaoxin 2; Lin, Qingxia3; Wang, Wo 1; Lv, Zhen 1; Chen, Xiaorong 1; Nie, Gang 4; Kuang, Li 1,5
发表日期	2021-03-01
发表期刊	JOURNAL OF AFFECTIVE DISORDERS 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Depression Relapse Prevent Psychotherapy Network meta-analysis
摘要	Background: The development of prophylactic interventions for major depressive disorder (MDD) is an important issue in clinical practice. We aimed to compare the relative efficacy of nonpharmacological interventions for relapse prevention in adult patients with MDD. Methods: Randomized controlled trials investigating nonpharmachological interventions for relapse prevention were included. A Bayesian network meta-analysis was performed. Hazard ratios are reported as effect sizes with 95% credible intervals. Global inconsistency, local inconsistency, heterogeneity, and transitivity were evaluated. Confidence for the results comparing the active treatment with control conditions or antidepressant medicine (ADM) was assessed. Results: Thirty-six trials were included. Most nonpharmacological interventions were various forms of psychotherapy; others were noninvasive neurostimulation techniques (3 studies with electroconvulsive therapy and 1 study with transcranial magnetic stimulation). Psychotherapy as a monotherapy following ADM or psychotherapy produced significantly better outcomes than control conditions, and there was no significant difference between psychotherapy and ADM. The combination of psychotherapy and ADM was superior to either treatment alone. The results were similar for patients with at least 3 previous episodes. Neurostimulation techniques were also superior to controls, either as a monotherapy or combined with ADM. Conclusions: Our study provided evidence that psychotherapy as a monotherapy following ADM or psychotherapy was effective and performed as well as ADM for relapse prevention. Neurostimulation techniques also showed promising results but more studies are needed to confirm their efficacy. These findings may be informative for clinical practice and inspire future research.
出版者	ELSEVIER
出版地	AMSTERDAM
ISSN	0165-0327
EISSN	1573-2517
卷号	282 页码:1255-1262
DOI	10.1016/j.jad.2021.01.025
页数	8
WOS类目	Clinical Neurology ; Psychiatry
WOS研究方向	Neurosciences & Neurology ; Psychiatry
WOS记录号	WOS:000619295400164
收录类别	SCIE ; SSCI ; PUBMED ; SCOPUS
URL	查看原文
PubMed ID	33601704
SCOPUSEID	2-s2.0-85099637192
社科自定义期刊分类	C类
通讯作者地址	[Nie, Gang]Department of Gastroenterology,University-Town Hospital of Chongqing Medical University,Shapingba District,Chongqing,401331,China
Scopus学科分类	Clinical Psychology;Psychiatry and Mental Health
引用统计	被引频次：2[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/2280
专题	精神医学学院_精神医学系附属第一医院
通讯作者	Nie, Gang
作者单位	1.Mental Health Center,University-Town Hospital of Chongqing Medical University,Chongqing,China; 2.Medical Department,University-Town Hospital of Chongqing Medical University,Chongqing,China; 3.Department of Psychiatry,The First Affiliated Hospital of Wenzhou Medical University,Zhejiang Province,China; 4.Department of Gastroenterology,University-Town Hospital of Chongqing Medical University,Shapingba District,Chongqing,401331,China; 5.Department of Psychiatry,The First Affiliated Hospital of Chongqing Medical University,Yuzhong District,Chongqing,400016,China
推荐引用方式 GB/T 7714	Zhou, Dongdong,Zhou, Xiaoxin,Lin, Qingxia,et al. Nonpharmacological interventions for relapse prevention in unipolar depression: A network meta-analysis[J]. JOURNAL OF AFFECTIVE DISORDERS,2021,282:1255-1262.
APA	Zhou, Dongdong., Zhou, Xiaoxin., Lin, Qingxia., Wang, Wo., Lv, Zhen., ... & Kuang, Li. (2021). Nonpharmacological interventions for relapse prevention in unipolar depression: A network meta-analysis. JOURNAL OF AFFECTIVE DISORDERS, 282, 1255-1262.
MLA	Zhou, Dongdong,et al."Nonpharmacological interventions for relapse prevention in unipolar depression: A network meta-analysis".JOURNAL OF AFFECTIVE DISORDERS 282(2021):1255-1262.