题名 | Nonpharmacological interventions for relapse prevention in unipolar depression: A network meta-analysis |
作者 | |
发表日期 | 2021-03-01 |
发表期刊 | JOURNAL OF AFFECTIVE DISORDERS 影响因子和分区 |
语种 | 英语 |
原始文献类型 | Article |
关键词 | Depression Relapse Prevent Psychotherapy Network meta-analysis |
摘要 | Background: The development of prophylactic interventions for major depressive disorder (MDD) is an important issue in clinical practice. We aimed to compare the relative efficacy of nonpharmacological interventions for relapse prevention in adult patients with MDD. Methods: Randomized controlled trials investigating nonpharmachological interventions for relapse prevention were included. A Bayesian network meta-analysis was performed. Hazard ratios are reported as effect sizes with 95% credible intervals. Global inconsistency, local inconsistency, heterogeneity, and transitivity were evaluated. Confidence for the results comparing the active treatment with control conditions or antidepressant medicine (ADM) was assessed. Results: Thirty-six trials were included. Most nonpharmacological interventions were various forms of psychotherapy; others were noninvasive neurostimulation techniques (3 studies with electroconvulsive therapy and 1 study with transcranial magnetic stimulation). Psychotherapy as a monotherapy following ADM or psychotherapy produced significantly better outcomes than control conditions, and there was no significant difference between psychotherapy and ADM. The combination of psychotherapy and ADM was superior to either treatment alone. The results were similar for patients with at least 3 previous episodes. Neurostimulation techniques were also superior to controls, either as a monotherapy or combined with ADM. Conclusions: Our study provided evidence that psychotherapy as a monotherapy following ADM or psychotherapy was effective and performed as well as ADM for relapse prevention. Neurostimulation techniques also showed promising results but more studies are needed to confirm their efficacy. These findings may be informative for clinical practice and inspire future research. |
出版者 | ELSEVIER |
出版地 | AMSTERDAM |
ISSN | 0165-0327 |
EISSN | 1573-2517 |
卷号 | 282页码:1255-1262 |
DOI | 10.1016/j.jad.2021.01.025 |
页数 | 8 |
WOS类目 | Clinical Neurology ; Psychiatry |
WOS研究方向 | Neurosciences & Neurology ; Psychiatry |
WOS记录号 | WOS:000619295400164 |
收录类别 | SCIE ; SSCI ; PUBMED ; SCOPUS |
URL | 查看原文 |
PubMed ID | 33601704 |
SCOPUSEID | 2-s2.0-85099637192 |
社科自定义期刊分类 | C类 |
通讯作者地址 | [Nie, Gang]Department of Gastroenterology,University-Town Hospital of Chongqing Medical University,Shapingba District,Chongqing,401331,China |
Scopus学科分类 | Clinical Psychology;Psychiatry and Mental Health |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | https://kms.wmu.edu.cn/handle/3ETUA0LF/2280 |
专题 | 精神医学学院_精神医学系 附属第一医院 |
通讯作者 | Nie, Gang |
作者单位 | 1.Mental Health Center,University-Town Hospital of Chongqing Medical University,Chongqing,China; 2.Medical Department,University-Town Hospital of Chongqing Medical University,Chongqing,China; 3.Department of Psychiatry,The First Affiliated Hospital of Wenzhou Medical University,Zhejiang Province,China; 4.Department of Gastroenterology,University-Town Hospital of Chongqing Medical University,Shapingba District,Chongqing,401331,China; 5.Department of Psychiatry,The First Affiliated Hospital of Chongqing Medical University,Yuzhong District,Chongqing,400016,China |
推荐引用方式 GB/T 7714 | Zhou, Dongdong,Zhou, Xiaoxin,Lin, Qingxia,et al. Nonpharmacological interventions for relapse prevention in unipolar depression: A network meta-analysis[J]. JOURNAL OF AFFECTIVE DISORDERS,2021,282:1255-1262. |
APA | Zhou, Dongdong., Zhou, Xiaoxin., Lin, Qingxia., Wang, Wo., Lv, Zhen., ... & Kuang, Li. (2021). Nonpharmacological interventions for relapse prevention in unipolar depression: A network meta-analysis. JOURNAL OF AFFECTIVE DISORDERS, 282, 1255-1262. |
MLA | Zhou, Dongdong,et al."Nonpharmacological interventions for relapse prevention in unipolar depression: A network meta-analysis".JOURNAL OF AFFECTIVE DISORDERS 282(2021):1255-1262. |
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