科研成果详情

题名Factors predicting the return of spontaneous circulation rate of cardiopulmonary resuscitation in China: Development and evaluation of predictive nomogram
作者
发表日期2024-08-30
发表期刊HELIYON   影响因子和分区
语种英语
原始文献类型Article
关键词Return of spontaneous circulation (ROSC) Cardiopulmonary resuscitation (CPR) Predictive model Cardiac arrest (CA) Nomogram
其他关键词HOSPITAL CARDIAC-ARREST ; TIDAL CARBON-DIOXIDE ; POSTRESUSCITATION CARE ; LIFE-SUPPORT ; SURVIVAL ; HYPERKALEMIA ; ASSOCIATION ; GUIDELINES ; PROGNOSIS ; SELECTINS
摘要Background: This study aimed to construct and internally validate a probability of the return of spontaneous circulation (ROSC) rate nomogram in a Chinese population of patients with cardiac arrest (CA). Methods: Patients with CA receiving standard cardiopulmonary resuscitation (CPR) were studied retrospectively. The minor absolute shrinkage and selection operator (LASSO) regression analysis and multivariable logistic regression evaluated various demographic and clinicopathological characteristics. A predictive nomogram was constructed and evaluated for accuracy and reliability using C-index, the area under the receiver operating characteristic curve (AUC), calibration plot, and decision curve analysis (DCA). Results: A cohort of 508 patients who had experienced CA and received standard CPR was randomly divided into training (70 %, n = 356) and validation groups (30 %, n = 152) for the study. LASSO regression analysis and multivariable logistic regression revealed that thirteen variables, such as age, CPR start time, Electric defibrillation, Epinephrine, Sodium bicarbonate (NaHCO3), CPR Compression duration, The postoperative prothrombin (PT) time, Lactate (Lac), Cardiac troponin (cTn), Potassium (K+), D-dimer, Hypertension (HBP), and Diabetes mellitus (DM), were found to be independent predictors of the ROSC rate of CPR. The nomogram model showed exceptional discrimination, with a C-index of 0.933 (95 % confidence interval: 0.882-0.984). Even in the internal validation, a remarkable C-index value of 0.926 (95 % confidence interval: 0.875-0.977) was still obtained. The accuracy and reliability of the model were also verified by the AUC of 0.923 in the training group and 0.926 in the validation group. The calibration curve showed the model agreed with the actual results. DCA suggested that the predictive nomogram had clinical utility. Conclusions: A predictive nomogram model was successfully established and proved to identify the influencing factors of the ROSC rate in patients with CA. During cardiopulmonary resuscitation, adjusting the emergency treatment based on the influence factors on ROSC rate is suggested to improve the treatment rate of patients with CA.
出版者CELL PRESS
ISSN2405-8440
EISSN2405-8440
卷号10期号:16
DOI10.1016/j.heliyon.2024.e35903
页数12
WOS类目Multidisciplinary Sciences
WOS研究方向Science & Technology - Other Topics
WOS记录号WOS:001294343700001
收录类别SCIE ; SCOPUS
URL查看原文
PubMed ID39224381
SCOPUSEID2-s2.0-85200867364
通讯作者地址[Lu, Guangrong]Wenzhou Med Univ, Yuying Childrens Hosp, 1111 Wenzhou Ave, Wenzhou 325000, Zhejiang, Peoples R China. ; [Lu, Guangrong]Wenzhou Med Univ, Affiliated Hosp 2, Dept Gastroenterol, 1111 Wenzhou Ave, Wenzhou 325000, Zhejiang, Peoples R China.
Scopus学科分类Multidisciplinary
引用统计
文献类型期刊论文
条目标识符https://kms.wmu.edu.cn/handle/3ETUA0LF/217469
专题附属第二医院
附属第二医院_消化内科
第二临床医学院、附属第二医院、育英儿童医院
通讯作者Lu, Guangrong
作者单位
1.Wenzhou Med Univ, Affiliated Hosp 2, Emergency Dept, Wenzhou, Peoples R China;
2.Wenzhou Med Univ, Yuying Childrens Hosp, 1111 Wenzhou Ave, Wenzhou 325000, Zhejiang, Peoples R China;
3.Wenzhou Med Univ, Affiliated Hosp 2, Dept Gastroenterol, 1111 Wenzhou Ave, Wenzhou 325000, Zhejiang, Peoples R China
第一作者单位附属第二医院;  第二临床医学院,附属第二医院、育英儿童医院
通讯作者单位第二临床医学院,附属第二医院、育英儿童医院;  附属第二医院;  消化内科
第一作者的第一单位附属第二医院
推荐引用方式
GB/T 7714
Yan, Leilei,Wang, Lingling,Zhou, Liangliang,et al. Factors predicting the return of spontaneous circulation rate of cardiopulmonary resuscitation in China: Development and evaluation of predictive nomogram[J]. HELIYON,2024,10(16).
APA Yan, Leilei., Wang, Lingling., Zhou, Liangliang., Jin, Qianqian., Liao, Dejun., ... & Lu, Guangrong. (2024). Factors predicting the return of spontaneous circulation rate of cardiopulmonary resuscitation in China: Development and evaluation of predictive nomogram. HELIYON, 10(16).
MLA Yan, Leilei,et al."Factors predicting the return of spontaneous circulation rate of cardiopulmonary resuscitation in China: Development and evaluation of predictive nomogram".HELIYON 10.16(2024).

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