题名 | Factors predicting the return of spontaneous circulation rate of cardiopulmonary resuscitation in China: Development and evaluation of predictive nomogram |
作者 | |
发表日期 | 2024-08-30 |
发表期刊 | HELIYON 影响因子和分区 |
语种 | 英语 |
原始文献类型 | Article |
关键词 | Return of spontaneous circulation (ROSC) Cardiopulmonary resuscitation (CPR) Predictive model Cardiac arrest (CA) Nomogram |
其他关键词 | HOSPITAL CARDIAC-ARREST ; TIDAL CARBON-DIOXIDE ; POSTRESUSCITATION CARE ; LIFE-SUPPORT ; SURVIVAL ; HYPERKALEMIA ; ASSOCIATION ; GUIDELINES ; PROGNOSIS ; SELECTINS |
摘要 | Background: This study aimed to construct and internally validate a probability of the return of spontaneous circulation (ROSC) rate nomogram in a Chinese population of patients with cardiac arrest (CA). Methods: Patients with CA receiving standard cardiopulmonary resuscitation (CPR) were studied retrospectively. The minor absolute shrinkage and selection operator (LASSO) regression analysis and multivariable logistic regression evaluated various demographic and clinicopathological characteristics. A predictive nomogram was constructed and evaluated for accuracy and reliability using C-index, the area under the receiver operating characteristic curve (AUC), calibration plot, and decision curve analysis (DCA). Results: A cohort of 508 patients who had experienced CA and received standard CPR was randomly divided into training (70 %, n = 356) and validation groups (30 %, n = 152) for the study. LASSO regression analysis and multivariable logistic regression revealed that thirteen variables, such as age, CPR start time, Electric defibrillation, Epinephrine, Sodium bicarbonate (NaHCO3), CPR Compression duration, The postoperative prothrombin (PT) time, Lactate (Lac), Cardiac troponin (cTn), Potassium (K+), D-dimer, Hypertension (HBP), and Diabetes mellitus (DM), were found to be independent predictors of the ROSC rate of CPR. The nomogram model showed exceptional discrimination, with a C-index of 0.933 (95 % confidence interval: 0.882-0.984). Even in the internal validation, a remarkable C-index value of 0.926 (95 % confidence interval: 0.875-0.977) was still obtained. The accuracy and reliability of the model were also verified by the AUC of 0.923 in the training group and 0.926 in the validation group. The calibration curve showed the model agreed with the actual results. DCA suggested that the predictive nomogram had clinical utility. Conclusions: A predictive nomogram model was successfully established and proved to identify the influencing factors of the ROSC rate in patients with CA. During cardiopulmonary resuscitation, adjusting the emergency treatment based on the influence factors on ROSC rate is suggested to improve the treatment rate of patients with CA. |
出版者 | CELL PRESS |
ISSN | 2405-8440 |
EISSN | 2405-8440 |
卷号 | 10期号:16 |
DOI | 10.1016/j.heliyon.2024.e35903 |
页数 | 12 |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
WOS记录号 | WOS:001294343700001 |
收录类别 | SCIE ; SCOPUS |
URL | 查看原文 |
PubMed ID | 39224381 |
SCOPUSEID | 2-s2.0-85200867364 |
通讯作者地址 | [Lu, Guangrong]Wenzhou Med Univ, Yuying Childrens Hosp, 1111 Wenzhou Ave, Wenzhou 325000, Zhejiang, Peoples R China. ; [Lu, Guangrong]Wenzhou Med Univ, Affiliated Hosp 2, Dept Gastroenterol, 1111 Wenzhou Ave, Wenzhou 325000, Zhejiang, Peoples R China. |
Scopus学科分类 | Multidisciplinary |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | https://kms.wmu.edu.cn/handle/3ETUA0LF/217469 |
专题 | 附属第二医院 附属第二医院_消化内科 第二临床医学院、附属第二医院、育英儿童医院 |
通讯作者 | Lu, Guangrong |
作者单位 | 1.Wenzhou Med Univ, Affiliated Hosp 2, Emergency Dept, Wenzhou, Peoples R China; 2.Wenzhou Med Univ, Yuying Childrens Hosp, 1111 Wenzhou Ave, Wenzhou 325000, Zhejiang, Peoples R China; 3.Wenzhou Med Univ, Affiliated Hosp 2, Dept Gastroenterol, 1111 Wenzhou Ave, Wenzhou 325000, Zhejiang, Peoples R China |
第一作者单位 | 附属第二医院; 第二临床医学院,附属第二医院、育英儿童医院 |
通讯作者单位 | 第二临床医学院,附属第二医院、育英儿童医院; 附属第二医院; 消化内科 |
第一作者的第一单位 | 附属第二医院 |
推荐引用方式 GB/T 7714 | Yan, Leilei,Wang, Lingling,Zhou, Liangliang,et al. Factors predicting the return of spontaneous circulation rate of cardiopulmonary resuscitation in China: Development and evaluation of predictive nomogram[J]. HELIYON,2024,10(16). |
APA | Yan, Leilei., Wang, Lingling., Zhou, Liangliang., Jin, Qianqian., Liao, Dejun., ... & Lu, Guangrong. (2024). Factors predicting the return of spontaneous circulation rate of cardiopulmonary resuscitation in China: Development and evaluation of predictive nomogram. HELIYON, 10(16). |
MLA | Yan, Leilei,et al."Factors predicting the return of spontaneous circulation rate of cardiopulmonary resuscitation in China: Development and evaluation of predictive nomogram".HELIYON 10.16(2024). |
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