Comparison between AWGC-cachexia and GLIM-malnutrition in patients with gastric cancer

doi:10.1016/j.ejso.2024.108580

科研成果详情

题名	Comparison between AWGC-cachexia and GLIM-malnutrition in patients with gastric cancer
作者	Wang, Su-Lin 1; Zhang, Feng-Min 2; Chen, Chen-Bin 1,3; Dong, Qian-Tong1; Liu, Shu1; Yu, Zhen 2; Shen, Xian 1; Zhuang, Cheng-Le 2
发表日期	2024-10
发表期刊	European Journal of Surgical Oncology 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Cachexia Malnutrition Gastric cancer Clinical outcome AWGC GLIM
摘要	Background: The newly released Asian Working Group for Cachexia (AWGC) criteria share similar diagnostic items with the Global Leadership Initiative on Malnutrition (GLIM) criteria. This study aims to compare the AWGC cachexia and GLIM malnutrition in patients with gastric cancer and investigate whether one diagnosis continues to be a prognostic factor in individuals diagnosed with the other condition. Methods: Data of patients who underwent radical gastrectomy for gastric adenocarcinoma were prospectively collected from 2013 to 2019. The AWGC and GLIM criteria were applied to diagnosis cachexia and malnutrition, respectively. Univariate and multivariate logistic and Cox regression were used to verify the effect of relevant factors on postoperative complications and overall survival. Results: A total of 1420 patients were included, among whom 174 (12.3 %) were diagnosed with AWGC-cachexia alone, 85 (6.0 %) were diagnosed with GLIM-malnutrition alone, and 324 (22.8 %) had both AWGC-cachexia and GLIM-malnutrition. Both AWGC-cachexia and GLIM-malnutrition were independent risk factors for complications and overall survival. When they coexisted, the odds ratios (OR) and hazard ratios (HR) tended to be higher. In the AWGC-cachexia subset, GLIM-malnutrition remained an independent risk factor (HR = 1.544, 95 % CI = 1.098-2.171, P = 0.012) for overall survival after the adjustment of confounding factors. Similarly, in the GLIMmalnutrition subset, AWGC-cachexia remained an independent risk factor for overall survival (HR = 1.697, 95 % CI = 1.087-2.650, P = 0.020). Patients with both cachexia and malnutrition had the worst overall survival. Conclusion: AWGC-cachexia and GLIM-malnutrition criteria were two non-redundancy tools in reflecting mortality risk in preoperative nutritional assessment.
资助项目	Basic Scientific Research Project of Wenzhou City [Y2023467]; National Key Clinical Specialty of the First Affiliated Hospital of Wenzhou Medical University
出版者	ELSEVIER SCI LTD
ISSN	0748-7983
EISSN	1532-2157
卷号	50 期号:10
DOI	10.1016/j.ejso.2024.108580
页数	6
WOS类目	Oncology ; Surgery
WOS研究方向	Oncology ; Surgery
WOS记录号	WOS:001291263600001
收录类别	SCIE ; SCOPUS ; PUBMED
URL	查看原文
PubMed ID	39116516
SCOPUSEID	2-s2.0-85200647744
通讯作者地址	[Shen, Xian]Wenzhou Med Univ, Affiliated Hosp 1, Dept Gastrointestinal Surg, 2 Fuxue Lane, Wenzhou 325000, Zhejiang, Peoples R China. ; [Zhuang, Cheng-Le]Tongji Univ, Shanghai Peoples Hosp 10, Colorectal Canc Ctr, Sch Med,Dept Gastrointestinal Surg, Shanghai, Peoples R China.
Scopus学科分类	Surgery;Oncology
SCOPUS_ID	SCOPUS_ID:85200647744
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/217434
专题	附属第一医院_胃肠外科附属第一医院
通讯作者	Shen, Xian; Zhuang, Cheng-Le
作者单位	1.Wenzhou Med Univ, Affiliated Hosp 1, Dept Gastrointestinal Surg, 2 Fuxue Lane, Wenzhou 325000, Zhejiang, Peoples R China; 2.Tongji Univ, Shanghai Peoples Hosp 10, Sch Med, Dept Gastrointestinal Surg, Shanghai, Peoples R China; 3.Wenzhou Med Univ, Zhejiang Key Lab Intelligent Canc Biomarker Discov, Affiliated Hosp 1, Wenzhou, Zhejiang, Peoples R China
第一作者单位	附属第一医院_胃肠外科
通讯作者单位	附属第一医院_胃肠外科
第一作者的第一单位	附属第一医院_胃肠外科
推荐引用方式 GB/T 7714	Wang, Su-Lin,Zhang, Feng-Min,Chen, Chen-Bin,et al. Comparison between AWGC-cachexia and GLIM-malnutrition in patients with gastric cancer[J]. European Journal of Surgical Oncology,2024,50(10).
APA	Wang, Su-Lin., Zhang, Feng-Min., Chen, Chen-Bin., Dong, Qian-Tong., Liu, Shu., ... & Zhuang, Cheng-Le. (2024). Comparison between AWGC-cachexia and GLIM-malnutrition in patients with gastric cancer. European Journal of Surgical Oncology, 50(10).
MLA	Wang, Su-Lin,et al."Comparison between AWGC-cachexia and GLIM-malnutrition in patients with gastric cancer".European Journal of Surgical Oncology 50.10(2024).