Malignant glaucoma treated by low-dose laser cycloplasty: a 1-year multicenter prospective non-comparative study

doi:10.18240/ijo.2024.07.08

科研成果详情

题名	Malignant glaucoma treated by low-dose laser cycloplasty: a 1-year multicenter prospective non-comparative study
作者	Lin, Hai-Shuang 1; Xu, Xiao-Ping 2; Zheng, Xuan-Li1; Wang, Ji-Bing 3; Fan, Su-Jie 4; Wu, Zuo-Hong 5; Cheng, Su-Mian 6; Zhao, Li-Jun 7; Cai, Qin-Hua 8; Zhang, Shao-Dan9,10; Liu, Shan-Shan 3; Lyu, Ai-Guo 4; Zhang, Ying 5; Chen, Hong 6; Jiang, Dan-Ni 7; Li, Wu-Liang 2; Congdon, Nathan 11,12; Tham, Clement C.13; He, Ming-Guang 14; Liang, Yuan-Bo9,10
发表日期	2024-07-18
发表期刊	INTERNATIONAL JOURNAL OF OPHTHALMOLOGY 影响因子和分区
语种	英语
原始文献类型	Article
关键词	anterior chamber reformation intraocular pressure low-dose laser cycloplasty malignant glaucoma anatomical success
其他关键词	AQUEOUS MISDIRECTION ; CHINESE PATIENTS ; MANAGEMENT ; OUTCOMES ; VITRECTOMY
摘要	AIM: To report a one-year clinical outcomes of low-dose laser cycloplasty (LCP) among malignant glaucoma patients. METHODS: In this prospective, multicenter, non- comparative clinical study, participants with malignant glaucoma were recruited and underwent LCP at eight ophthalmic centers in China. Patients were followed up at 1wk, 1, 3, 6, and 12mo. Intraocular pressure (IOP), number of glaucoma medications, anterior chamber depth (ACD), and complications were recorded. Anatomical success was defined as the reformation of the anterior chamber based on slit-lamp biomicroscopy. Recurrence was defined by the presence of a shallow or flat anterior chamber after initial recovery from treatment. RESULTS: A total of 34 eyes received LCP. Mean IOP and medications decreased from 36.1 +/- 11.5 mm Hg with 3.3 +/- 1.5 glaucoma medications pre-treatment to 20.9 +/- 9.8 mm Hg (P<0.001) P <0.001) with 2.9 +/- 1.6 medications (P=0.046) P =0.046) at 1d, and 17.4 +/- 6.7 mm Hg (P<0.001) P <0.001) with 1.3 +/- 1.7 medications (P<0.00 P <0.00 1) at 12mo. The ACD increased from 1.1 +/- 0.8 mm at baseline to 1.7 +/- 1.0 mm and to 2.0 +/- 0.5 mm at 1d and 12mo, respectively. A total of 32 (94.1%) eyes achieved initial anatomical success. During follow-up, 2 (5.9%) eyes failed and 8 (23.5%) eyes relapsed, yielding a 12-month anatomical success rate of 64.3%. Complications including anterior synechia (8.82%), choroidal/ciliary detachment (5.88%) and hypopyon (2.94%) were observed within 1wk. CONCLUSION: LCP is simple, safe, and effective in reforming the anterior chamber in malignant glaucoma.
资助项目	Program for Zhejiang Leading Talent of ST Innovation [2021R52012]; Development Projects of Zhejiang Province [2022C03112]; Innovation Team Program of Wenzhou
出版者	IJO PRESS
ISSN	2222-3959
EISSN	2227-4898
卷号	17 期号:7 页码:1248-1254
DOI	10.18240/ijo.2024.07.08
页数	7
WOS类目	Ophthalmology
WOS研究方向	Ophthalmology
WOS记录号	WOS:001272879100008
收录类别	SCIE ; SCOPUS ; PUBMED
URL	查看原文
PubMed ID	39026914
SCOPUSEID	2-s2.0-85197619487
通讯作者地址	[Liang, Yuan-Bo]Wenzhou Med Univ, Eye Hosp, Natl Clin Res Ctr Ocular Dis, Wenzhou 325027, Zhejiang, Peoples R China.
Scopus学科分类	Ophthalmology
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/216687
专题	眼视光学院（生物医学工程学院）、附属眼视光医院眼视光学院（生物医学工程学院）、附属眼视光医院_杭州院区_青光眼专科
通讯作者	Liang, Yuan-Bo
作者单位	1.Wenzhou Med Univ, Wenzhou 325027, Zhejiang, Peoples R China; 2.Ningbo Eye Hosp, Ningbo 315100, Zhejiang, Peoples R China; 3.Weifang Eye Hosp, Weifang 261000, Shandong, Peoples R China; 4.Handan Eye Hosp, Handan 056000, Hebei, Peoples R China; 5.Aier Eye Hosp Wuhan, Wuhan 430061, Hubei, Peoples R China; 6.Hebei Eye Hosp, Xingtai 054001, Hebei, Peoples R China; 7.Third Peoples Hosp Dalian, Dalian 116033, Liaoning, Peoples R China; 8.Suzhou Univ, Affiliated Hosp 1, Suzhou 215031, Jiangsu, Peoples R China; 9.Wenzhou Med Univ, Eye Hosp, Natl Clin Res Ctr Ocular Dis, Wenzhou 325027, Zhejiang, Peoples R China; 10.Wenzhou Med Univ, Glaucoma Res Inst, Wenzhou 325027, Zhejiang, Peoples R China; 11.Queens Univ Belfast, Ctr Publ Hlth, Belfast BT7 1NN, North Ireland; 12.Orbis Int, New York, NY USA; 13.Chinese Univ Hong Kong, Dept Ophthalmol & Visual Sci, Hong Kong 999077, Peoples R China; 14.Univ Melbourne, Royal Victorian Eye & Ear Hosp, Ctr Eye Res Australia, East Melbourne, Vic 3000, Australia
第一作者单位	温州医科大学
通讯作者单位	眼视光学院（生物医学工程学院）、附属眼视光医院
第一作者的第一单位	温州医科大学
推荐引用方式 GB/T 7714	Lin, Hai-Shuang,Xu, Xiao-Ping,Zheng, Xuan-Li,et al. Malignant glaucoma treated by low-dose laser cycloplasty: a 1-year multicenter prospective non-comparative study[J]. INTERNATIONAL JOURNAL OF OPHTHALMOLOGY,2024,17(7):1248-1254.
APA	Lin, Hai-Shuang., Xu, Xiao-Ping., Zheng, Xuan-Li., Wang, Ji-Bing., Fan, Su-Jie., ... & Liang, Yuan-Bo. (2024). Malignant glaucoma treated by low-dose laser cycloplasty: a 1-year multicenter prospective non-comparative study. INTERNATIONAL JOURNAL OF OPHTHALMOLOGY, 17(7), 1248-1254.
MLA	Lin, Hai-Shuang,et al."Malignant glaucoma treated by low-dose laser cycloplasty: a 1-year multicenter prospective non-comparative study".INTERNATIONAL JOURNAL OF OPHTHALMOLOGY 17.7(2024):1248-1254.