Raman-integrated optical photothermal infrared microscopy: technology and applications

doi:10.1016/B978-0-323-91249-5.00004-1

科研成果详情

题名	Raman-integrated optical photothermal infrared microscopy: technology and applications
作者	Li, Xiaojie 1; Xu, Jiabao 2; Cheng, Ji-Xin 3,4
来源专著	Molecular and Laser Spectroscopy: Advances and Applications: Volume 3
语种	英语
原始文献类型	Book Chapter
关键词	Living cell Materials Optical photothermal infrared imaging Optical photothermal infrared spectroscopy Raman spectroscopy
摘要	The two primary modalities of vibrational spectroscopy, IR and Raman spectroscopy, provide complementary and comprehensive chemical and molecular information. Whereas Fourier-transform infrared (FTIR) microscopy suffers from low spatial resolution and strong water absorption background, the emerging technique of optical photothermal infrared (O-PTIR) microscopy is introduced with the advantages of reaching the spatial resolution at the nanometer scale. More recently, O-PTIR microscopy has been integrated with Raman spectroscopy, which offers submicron infrared photothermal images and simultaneous infrared and Raman spectra that complement each other. This chapter discusses the working principle, instrumentation, and performances of the Raman-integrated O-PTIR microscopy. Raman-integrated O-PTIR microscopy has high application potential, especially in the field of biomedicine. The latest applications include characterization of lipid droplets in single cells, fingerprinting a single bacterium, and phenotyping bacterial responses to drugs. Applications in the chemical and material analysis are also presented.
出版者	Elsevier
卷号	3
ISBN	[{$=9780323912495}, {$=9780323914703}]
页码	281-303
DOI	10.1016/B978-0-323-91249-5.00004-1
收录类别	SCOPUS
出版日期	2022
URL	查看原文
Scopus记录号	2-s2.0-85143364376
Scopus学科分类	Chemistry (all)
引用统计
文献类型	专著章节
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/214422
专题	仁济学院_眼视光、生物医学工程学部
作者单位	1.School of Biomedical Engineering,Wenzhou Medical University,Wenzhou,China; 2.Department of Engineering Science,University of Oxford,Oxford,United Kingdom; 3.Department of Electrical and Computer Engineering,Boston University,Boston,United States; 4.Department of Biomedical Engineering,Boston University,Boston,United States
第一作者单位	仁济学院_眼视光、生物医学工程学部
第一作者的第一单位	仁济学院_眼视光、生物医学工程学部
推荐引用方式 GB/T 7714	Li, Xiaojie,Xu, Jiabao,Cheng, Ji-Xin. Raman-integrated optical photothermal infrared microscopy: technology and applications:Elsevier,2022:281-303.