Study on sex differences and potential clinical value of three-dimensional computerized tomography pelvimetry in rectal cancer patients

doi:10.4251/wjgo.v16.i3.773

科研成果详情

题名	Study on sex differences and potential clinical value of three-dimensional computerized tomography pelvimetry in rectal cancer patients
作者	Zhou, Xiao-Cong1; Ke, Fei-Yue2; Dhamija, Gaurav 3; Chen, Hao 2; Wang, Qiang 4
发表日期	2024
发表期刊	World Journal of Gastrointestinal Oncology; 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Computerized tomography Pelvimetry Rectal cancer Sex differences Three-dimensional reconstruction
其他关键词	TOTAL MESORECTAL EXCISION ; ANTERIOR RESECTION ; IMPACT ; INDEX
摘要	BACKGROUND Laparoscopic rectal cancer radical surgery is a complex procedure affected by various factors. However, the existing literature lacks standardized parameters for the pelvic region and soft tissues, which hampers the establishment of consistent conclusions. AIM To comprehensively assess 16 pelvic and 7 soft tissue parameters through computerized tomography (CT)-based three-dimensional (3D) reconstruction, providing a strong theoretical basis to address challenges in laparoscopic rectal cancer radical surgery. METHODS We analyzed data from 218 patients who underwent radical laparoscopic surgery for rectal cancer, and utilized CT data for 3D pelvic reconstruction. Specific anatomical points were carefully marked and measured using advanced 3D modeling software. To analyze the pelvic and soft tissue parameters, we employed statistical methods including paired sample t-tests, Wilcoxon rank-sum tests, and correlation analysis. RESULTS The investigation highlighted significant sex disparities in 14 pelvic bone parameters and 3 soft tissue parameters. Males demonstrated larger measurements in pelvic depth and overall curvature, smaller measurements in pelvic width, a larger mesorectal fat area, and a larger anterior-posterior abdominal diameter. By contrast, females exhibited wider pelvises, shallower depth, smaller overall curvature, and an increased amount of subcutaneous fat tissue. However, there were no significant sex differences observed in certain parameters such as sacral curvature height, superior pubococcygeal diameter, rectal area, visceral fat area, waist circumference, and transverse abdominal diameter. CONCLUSION The reconstruction of 3D CT data enabled accurate pelvic measurements, revealing significant sex differences in both pelvic and soft tissue parameters. This study design offer potential in predicting surgical difficulties and creating personalized surgical plans for male rectal cancer patients with a potentially “difficult pelvis”, ultimately improving surgical outcomes. Further research and utilization of these parameters could lead to enhanced surgical methods and patient care in laparoscopic rectal cancer radical surgery.
资助项目	Zhejiang Province Public Welfare Technology Application Research Funding Project[LGC21H160002,Y20220885];Wenzhou Medical University[JG2021167];
出版者	BAISHIDENG PUBLISHING GROUP INC
ISSN	1948-5204
卷号	16 期号:3 页码:773-786
DOI	10.4251/wjgo.v16.i3.773
页数	15
WOS类目	Oncology ; Gastroenterology & Hepatology
WOS研究方向	Oncology ; Gastroenterology & Hepatology
WOS记录号	WOS:001198236100017
收录类别	SCOPUS ; SCIE
URL	查看原文
PubMed ID	38577473
SCOPUSEID	2-s2.0-85188515245
通讯作者地址	[Wang, Qiang]Department of Radiology,The Dingli Clinical Institute of Wenzhou Medical University (Wenzhou Central Hospital),No. 252 Baili East Road, Zhejiang Province,Wenzhou,325000,China
Scopus学科分类	Oncology;Gastroenterology
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/212596
专题	温州医科大学国际教育学院
通讯作者	Wang, Qiang
作者单位	1.Department of Colorectal Surgery,The Dingli Clinical Institute of Wenzhou Medical University (Wenzhou Central Hospital),Zhejiang Province,Wenzhou,325000,China; 2.Postgraduate Training Base Alliance of Wenzhou Medical University,Wenzhou Central Hospital,Zhejiang Province,Wenzhou,325000,China; 3.School of International Studies,Wenzhou Medical University,Zhejiang Province,Wenzhou,325000,China; 4.Department of Radiology,The Dingli Clinical Institute of Wenzhou Medical University (Wenzhou Central Hospital),Zhejiang Province,Wenzhou,325000,China
第一作者单位	温州医科大学
通讯作者单位	温州医科大学
第一作者的第一单位	温州医科大学
推荐引用方式 GB/T 7714	Zhou, Xiao-Cong,Ke, Fei-Yue,Dhamija, Gaurav,et al. Study on sex differences and potential clinical value of three-dimensional computerized tomography pelvimetry in rectal cancer patients[J]. World Journal of Gastrointestinal Oncology;,2024,16(3):773-786.
APA	Zhou, Xiao-Cong, Ke, Fei-Yue, Dhamija, Gaurav, Chen, Hao, & Wang, Qiang. (2024). Study on sex differences and potential clinical value of three-dimensional computerized tomography pelvimetry in rectal cancer patients. World Journal of Gastrointestinal Oncology;, 16(3), 773-786.
MLA	Zhou, Xiao-Cong,et al."Study on sex differences and potential clinical value of three-dimensional computerized tomography pelvimetry in rectal cancer patients".World Journal of Gastrointestinal Oncology; 16.3(2024):773-786.