科研成果详情

题名Abnormal structural covariance networks in young adults with recent cannabis use
作者
发表日期2024-08
发表期刊Addictive behaviors   影响因子和分区
语种英语
原始文献类型Journal Article
关键词Global network measures Nodal degree Recent cannabis use Structural covariance networks Young adults
其他关键词HUMAN CONNECTOME PROJECT ; CORTICAL THICKNESS ; QUALITY-CONTROL ; WORKING-MEMORY ; CONNECTIVITY ; CORTEX ; AREA
摘要

Recent cannabis use (RCU) exerts adverse effects on the brain. However, the effect of RCU on structural covariance networks (SCNs) is still unclear. This retrospective cross-sectional study aimed to explore the effects of RCU on SCNs in young adults in terms of whole cerebral cortical thickness (CT) and cortical surface area (CSA)., A total of 117 participants taking tetrahydrocannabinol (RCU group) and 896 participants not using cannabis (control group) were included in this study. All participants underwent MRI scanning following urinalysis screening, after which FreeSurfer 5.3 was used to calculate the CT and CSA, and SCNs matrices were constructed by Brain Connectivity Toolbox. Subsequently, the global and nodal network measures of the SCNs were computed based on these matrices. A nonparametric permutation test was used to investigate the group differences by Matlab., Regarding global network measures of CT, young adults with RCU exhibited altered small-worldness (P = 0.020) and clustering coefficient (P = 0.031) compared to controls, whereas there were no significant group differences in terms of SCNs constructed with CSA. Additionally, SCNs based on CT and CSA displayed abnormal nodal degree, nodal efficiency, and nodal betweenness centrality in vital brain regions of the triple network, including the dorsolateral and ventrolateral prefrontal cortex, and anterior cingulate cortex., The effects of RCU on brain structure in young adults can be detected by SCNs, in which structural abnormalities in the triple network are dominant, indicating that RCU can be detrimental to brain function.

资助项目Wenzhou Medical University[QTJ23027]
出版者PERGAMON-ELSEVIER SCIENCE LTD
ISSN0306-4603
EISSN1873-6327
卷号155
DOI10.1016/j.addbeh.2024.108029
页数8
WOS类目Psychology, Clinical ; Substance Abuse
WOS研究方向Psychology ; Substance Abuse
WOS记录号WOS:001224404000001
收录类别SCIE ; SSCI ; SSCI ; PUBMED ; SCOPUS
URL查看原文
PubMed ID38593597
SCOPUSEID2-s2.0-85189668739
通讯作者地址[Xu, Hui]School of Mental Health,Wenzhou Medical University,Wenzhou,325035,China
Scopus学科分类Medicine (miscellaneous);Clinical Psychology;Toxicology;Psychiatry and Mental Health
引用统计
文献类型期刊论文
条目标识符https://kms.wmu.edu.cn/handle/3ETUA0LF/211102
专题附属第一医院
精神医学学院
其他_附属康宁医院(温州市康宁医院)
通讯作者Xu, Hui
作者单位
1.School of Mental Health,Wenzhou Medical University,Wenzhou,325035,China;
2.The Affiliated Kangning Hospital of Wenzhou Medical University,Zhejiang Provincial Clinical Research Center for Mental Disorder,Wenzhou,325007,China;
3.Department of Neurology,The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061,China
第一作者单位精神医学学院;  附属康宁医院(温州市康宁医院)
通讯作者单位精神医学学院
第一作者的第一单位精神医学学院
推荐引用方式
GB/T 7714
Li, Jiahao,Xu, Hui. Abnormal structural covariance networks in young adults with recent cannabis use[J]. Addictive behaviors,2024,155.
APA Li, Jiahao, & Xu, Hui. (2024). Abnormal structural covariance networks in young adults with recent cannabis use. Addictive behaviors, 155.
MLA Li, Jiahao,et al."Abnormal structural covariance networks in young adults with recent cannabis use".Addictive behaviors 155(2024).

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