c-Myc-activated long non-coding RNA LINC01050 promotes gastric cancer growth and metastasis by sponging miR-7161-3p to regulate SPZ1 expression (vol 40, 351, 2021)

doi:10.1186/s13046-024-02948-6

科研成果详情

名称	c-Myc-activated long non-coding RNA LINC01050 promotes gastric cancer growth and metastasis by sponging miR-7161-3p to regulate SPZ1 expression (vol 40, 351, 2021)
作者	Ji, Ziwei 1; Tang, Tianbin 2; Chen, Mengxia1; Dong, Buyuan 1; Sun, Wenjing 2; Wu, Nan 1; Chen, Hao1; Feng, Qian 1; Yang, Xingyi 1; Jin, Rong1; Jiang, Lei2
发表期刊	JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
语种	英语
原始文献类型	Correction
摘要	Following the publication of the original article [1], the authors identified a minor error in image-typesetting in Fig. 5a; specifically, the lower panels in Fig. 5a, the incorrect representative image used for invasion transwell assays of KATO III cells transfected with si-LINC01050#1. (Figure presented.) LINC01050 knockdown inhibits gastric cancer cell migration and invasion in vitro and metastasis in vivo. a Migration and invasion abilities of BGC823 and KATO III cells transfected with si-NC (negative control), si-LINC01050#1, or si-LINC01050#2, as assessed by Transwell assays. The data are presented as the mean ± SD. *P < 0.01. Scale bar = 100 μm. b Western blot analysis of EMT-related protein expression (E-cadherin and vimentin) in BGC823 and KATO III cells transfected with si-NC (negative control), si-LINC01050#1, or si-LINC01050#2. GAPDH was used as an internal control. Data are presented as mean ± SD (n = 3). P < 0.05, *P < 0.01. c Statistical quantification of lung metastatic nodules (n = 5) produced after BGC823 cells transduced with lentiviral shNC or shLINC01050 were injected into nude mice via the tail vein. The data are represented as the mean ± SD. P < 0.05. d Representative photographs showing the macroscopic appearance of lung metastases. e Body weights of mice were recorded after a tail vein injection of the BGC823 cells transduced with lentiviral shNC or shLINC01050. Data are presented as mean ± SD (n = 5).*P < 0.05 The corrected figure is given below. The correction does not have any effect on the final conclusions of the paper.
出版者	BMC
ISSN	0392-9078
EISSN	1756-9966
卷号	43
期号	1
DOI	10.1186/s13046-024-02948-6
页数	3
WOS类目	Oncology
WOS研究方向	Oncology
WOS记录号	WOS:001157367200001
收录类别	SCIE ; PUBMED ; SCOPUS
发布日期	2024-02-05
URL	查看原文
PubMed ID	38311776
通讯作者地址	[Jin, Rong]Wenzhou Med Univ, Affiliated Hosp 1, Dept Gastroenterol, Wenzhou 325000, Peoples R China. ; [Jiang, Lei]Wenzhou Med Univ, Affiliated Hosp 1, Cent Lab, Wenzhou 325000, Peoples R China.
Scopus学科分类	Oncology;Cancer Research
SCOPUSEID	2-s2.0-85184099363
SCOPUS_ID	SCOPUS_ID:85184099363
引用统计
文献类型	其他
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/210135
专题	附属第一医院附属第一医院_消化内科
通讯作者	Jin, Rong; Jiang, Lei
作者单位	1.Wenzhou Med Univ, Affiliated Hosp 1, Dept Gastroenterol, Wenzhou 325000, Peoples R China; 2.Wenzhou Med Univ, Affiliated Hosp 1, Cent Lab, Wenzhou 325000, Peoples R China
第一作者单位	附属第一医院; 消化内科
通讯作者单位	附属第一医院; 消化内科
推荐引用方式 GB/T 7714	Ji, Ziwei,Tang, Tianbin,Chen, Mengxia,et al. c-Myc-activated long non-coding RNA LINC01050 promotes gastric cancer growth and metastasis by sponging miR-7161-3p to regulate SPZ1 expression (vol 40, 351, 2021). 2024.