Enhancing Prognostic Assessment for Influenza-Associated Pneumonia: An Examination of Contributing Risk Factors

科研成果详情

题名	Enhancing Prognostic Assessment for Influenza-Associated Pneumonia: An Examination of Contributing Risk Factors
作者	Lin, Yi 1; Li, Yuping2; Lian, Xiang 1; Qian, Zhenping 1; Wang, Weijie1; Zhu, Pingguang 1
发表日期	2023
发表期刊	ALTERNATIVE THERAPIES IN HEALTH AND MEDICINE 影响因子和分区
语种	英语
原始文献类型	Article
摘要	Objective . This study aims to analyze the prognostic risk factors influencing patient outcomes in cases of influenza-associated pneumonia. Methods . We comprehensively analysed clinical data from patients admitted to the First Affiliated Hospital of Wenzhou Medical University between December 2017 and April 2019. Patients with confirmed influenza-associated pneumonia, determined through nucleic acid detection in throat swabs or sputum samples, were included in the study. The collected data were meticulously analyzed to identify significant prognostic risk factors. Results . A total of 151 patients diagnosed with influenza-associated pneumonia were included in the final analysis, yielding a fatality rate of 19.87% (30/151). The application of multivariate regression analysis revealed that several independent risk factors significantly affected the prognosis of patients afflicted with influenza-associated pneumonia. These included lymphocyte count (L), oxygenation index (O), albumin (A), and urinary (U) levels. Receiver operating characteristic (ROC) curve analysis further elucidated the prognostic value of these factors. Specifically, the Composite Index LOAU (Lymphocyte, Oxygenation index, Albumin, Urinary) demonstrated a robust area under the curve (AUC) of 0.909 (95% CI: 0.851-0.950), surpassing the performance of established scoring systems, such as the pneumonia severity index (PSI) (AUC = 0.746), Apache II (AUC = 0.732), and CURB-65 (AUC = 0.662). These differences were statistically significant (P < .05). Conclusions . The prognosis of influenza-associated pneumonia can be effectively predicted by assessing peripheral blood parameters, including lymphocyte count, albumin level, urinary markers, and the oxygenation index upon admission. Notably, the Composite Index LOAU, as a comprehensive amalgamation of these factors, holds promising potential to enhance prognostic precision and management outcomes in cases of influenza-associated pneumonia.
资助项目	National Natural Science Foundation of China [81970066]
出版者	InnoVision Professional Media
ISSN	1078-6791
卷号	29 期号:8 页码:370-375
页数	6
WOS类目	Integrative & Complementary Medicine
WOS研究方向	Integrative & Complementary Medicine
WOS记录号	WOS:001137669200061
收录类别	SCIE
PubMed ID	37652408
通讯作者地址	[Lian, Xiang]Wenzhou Med Univ, Xiangshan Hosp, Dept Resp, Ningbo, Peoples R China.
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/207313
专题	温州医科大学第一临床医学院（信息与工程学院）、附属第一医院_内科学_呼吸与危重症医学科
通讯作者	Lian, Xiang
作者单位	1.Wenzhou Med Univ, Xiangshan Hosp, Dept Resp, Ningbo, Peoples R China; 2.Wenzhou Med Univ, Affiliated Hosp 1, Dept Resp & Crit Care Med, Wenzhou, Peoples R China
第一作者单位	温州医科大学
通讯作者单位	温州医科大学
第一作者的第一单位	温州医科大学
推荐引用方式 GB/T 7714	Lin, Yi,Li, Yuping,Lian, Xiang,et al. Enhancing Prognostic Assessment for Influenza-Associated Pneumonia: An Examination of Contributing Risk Factors[J]. ALTERNATIVE THERAPIES IN HEALTH AND MEDICINE,2023,29(8):370-375.
APA	Lin, Yi, Li, Yuping, Lian, Xiang, Qian, Zhenping, Wang, Weijie, & Zhu, Pingguang. (2023). Enhancing Prognostic Assessment for Influenza-Associated Pneumonia: An Examination of Contributing Risk Factors. ALTERNATIVE THERAPIES IN HEALTH AND MEDICINE, 29(8), 370-375.
MLA	Lin, Yi,et al."Enhancing Prognostic Assessment for Influenza-Associated Pneumonia: An Examination of Contributing Risk Factors".ALTERNATIVE THERAPIES IN HEALTH AND MEDICINE 29.8(2023):370-375.