Surgical resection of pulmonary metastases from colorectal cancer: 11 years of experiences

doi:10.1371/journal.pone.0175284

科研成果详情

题名	Surgical resection of pulmonary metastases from colorectal cancer: 11 years of experiences
作者	Cao, Guoquan1; Cheng, Dezhi2; Ye, Lechi3; Pan, Yiyuan 3; Yang, Fan 3; Lyu, Shixu 3
发表日期	2017-04-10
发表期刊	PLOS ONE 影响因子和分区
语种	英语
原始文献类型	Article
其他关键词	PROGNOSTIC-FACTORS ; LUNG METASTASES ; RADIOFREQUENCY ABLATION ; CARCINOMA ; SURVIVAL ; RECURRENCE
摘要	Objective To analyze the benefits and prognostic factors after surgical resection of pulmonary metastases from colorectal cancer (CRC). Methods From Jan. 2004 to Jan. 2015, continuous 88 cases diagnosed with pulmonary metastases from CRC, including 15 cases of synchronous metastases and 73 metachronous metastases, were analyzed in the retrospective study. Results All of these 88 cases underwent curative pulmonary resection including 8 cases of simultaneous surgery. The one-year, three-year and five-year survival of the 88 cases were 93.4%, 60.2% and 35.7%, respectively. 63 patients just have one metastasis, and 25 patients have more than one metastasis. Additionally, the one-year, three-year and five-year survival was 98.1%, 70.2% and 40.3% respectively in one metastasis group, while 80.1%, 37.9% and 22.5% respectively in more than one metastasis group (p = 0.003). DFS of 37 metachronous metastases were equal or greater than 18 months, and DFS of 36 metachronous metastases were less than 18 months. The one-year, three-year and five-year survival was 97.8%, 77.9% and 41.4% respectively in the DFS >= 18 month group, while 88.2%, 44.6% and 28.1% respectively in the DFS<18 month group ( p = 0.01). Conclusion Surgical resection of pulmonary metastases from colorectal cancer can improve survival rate in selected patients. It seems that the number of metastases is an independence prognostic factor in surgical treatment. Furthermore, longer DFI implies longer survival for resectable CRC pulmonary metastases.
资助项目	zhejiang provincial natural science foundationNatural Science Foundation of Zhejiang Province [LY15H160058, LY15H030016]; Wenzhou city science and technology projects [2015Y0452]
出版者	PUBLIC LIBRARY SCIENCE
出版地	SAN FRANCISCO
ISSN	1932-6203
卷号	12 期号:4 页码:e0175284.
DOI	10.1371/journal.pone.0175284
页数	10
WOS类目	Multidisciplinary Sciences
WOS研究方向	Science & Technology - Other Topics
WOS记录号	WOS:000399954800024
收录类别	SCIE ; PUBMED ; SCOPUS
URL	查看原文
PubMed ID	28394911
PMC记录号	PMC5386242
SCOPUSEID	2-s2.0-85017197682
通讯作者地址	[Cao, Guoquan]Department of Radiology,The,First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China
Scopus学科分类	Multidisciplinary
引用统计	被引频次：6[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/19183
专题	第一临床医学院（信息与工程学院）、附属第一医院_影像医学与核医学_放射科附属第一医院_心胸外科附属第一医院_肿瘤外科
通讯作者	Cao, Guoquan
作者单位	1.Department of Radiology,The,First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China; 2.Department of Cardiothoracic Surgery,The,First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China; 3.Department of Surgical Oncology,The,First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China
第一作者单位	附属第一医院
通讯作者单位	附属第一医院
第一作者的第一单位	附属第一医院
推荐引用方式 GB/T 7714	Cao, Guoquan,Cheng, Dezhi,Ye, Lechi,et al. Surgical resection of pulmonary metastases from colorectal cancer: 11 years of experiences[J]. PLOS ONE,2017,12(4):e0175284..
APA	Cao, Guoquan, Cheng, Dezhi, Ye, Lechi, Pan, Yiyuan, Yang, Fan, & Lyu, Shixu. (2017). Surgical resection of pulmonary metastases from colorectal cancer: 11 years of experiences. PLOS ONE, 12(4), e0175284..
MLA	Cao, Guoquan,et al."Surgical resection of pulmonary metastases from colorectal cancer: 11 years of experiences".PLOS ONE 12.4(2017):e0175284..