题名 | Therapeutic effects of traditional Chinese medicine (Maxingshigan-Weijing Decoction) on COVID-19: An open-label randomized controlle d trial |
作者 | |
发表日期 | 2021 |
发表期刊 | INTEGRATIVE MEDICINE RESEARCH 影响因子和分区 |
语种 | 英语 |
原始文献类型 | Article |
关键词 | COVID-19 Maxingshigan-Weijing decoction Symptom recovery Traditional Chinese medicine |
摘要 | Background: Wenzhou has achieved great progress in the prevention and control of the growing coronavirus disease 2019 (COVID-19) pandemic, and traditional Chinese medicine (TCM) has played an indispensable role in this fight. This study aimed to investigate the efficacy of Maxingshigan-Weijing decoction (MWD) in treating infected patients. Methods: This study was an open-label randomized controlled trial. Inpatients with mild or moderate symptoms caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection were randomly treated with routine supportive care alone or a combination of routine supportive care and MWD. The primary outcome was the rate of symptom (fever, fatigue, cough and difficulty breathing) recovery. Results: Fifty-nine inpatients were enrolled, of whom 29 received routine supportive care alone (control group) and 30 received combination therapy (treatment group). The rate of symptom recovery was significantly higher in the treatment group than in the control group. The time to recovery of fever (3 vs. 7 days), fatigue (9 vs. 12 days), coughing (9 vs. 14 days) and difficulty breathing (4.5 vs. 9.5 days) was also significantly shorter in the treatment group (all p < 0.001). The syndrome score was lower after MWD treatment. However, neither group differed in the viral assay findings, hospitalization days, medication time or the rate of conversion to severe cases. Conclusions: MWD increased the rate of symptom recovery and shortened the time to recovery of clinical symptoms without deterioration to death or critical care. These findings may provide opportunities for the use of complementary medicine in treating this infection. (C) 2021 Korea Institute of Oriental Medicine. Published by Elsevier B.V. |
资助项目 | Wenzhou Municipal Science and Technology Bureau (CN) [ZY202003] |
出版者 | ELSEVIER |
出版地 | AMSTERDAM |
ISSN | 2213-4220 |
EISSN | 2213-4239 |
卷号 | 10期号:Suppl页码:100782 |
DOI | 10.1016/j.imr.2021.100782 |
页数 | 7 |
WOS类目 | Integrative & Complementary Medicine |
WOS研究方向 | Integrative & Complementary Medicine |
WOS记录号 | WOS:000731606500006 |
收录类别 | SCIE ; PUBMED ; SCOPUS |
URL | 查看原文 |
PubMed ID | 34660195 |
PMC记录号 | PMC8507566 |
SCOPUSEID | 2-s2.0-85117587727 |
通讯作者地址 | [Cheng, Jinguo]Department of Traditional Chinese Medicine,The First Affiliated Hospital of Wenzhou Medical University,Nanbaixiang, Ouhai District,Wenzhou,China |
Scopus学科分类 | Complementary and Alternative Medicine |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | https://kms.wmu.edu.cn/handle/3ETUA0LF/19088 |
专题 | 附属第一医院_中医科 第二临床医学院、附属第二医院、育英儿童医院_中医系 |
通讯作者 | Cheng, Jinguo |
作者单位 | 1.Department of Traditional Chinese Medicine,The First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China; 2.School of Traditional Chinese Medicine,Wenzhou Medical University,Wenzhou,China |
第一作者单位 | 附属第一医院; 第一临床医学院(信息与工程学院)、附属第一医院 |
通讯作者单位 | 附属第一医院; 第一临床医学院(信息与工程学院)、附属第一医院 |
第一作者的第一单位 | 附属第一医院 |
推荐引用方式 GB/T 7714 | Zeng, Congcong,Yuan, Zhengzhong,Zhu, Jiahui,et al. Therapeutic effects of traditional Chinese medicine (Maxingshigan-Weijing Decoction) on COVID-19: An open-label randomized controlle d trial[J]. INTEGRATIVE MEDICINE RESEARCH,2021,10(Suppl):100782. |
APA | Zeng, Congcong., Yuan, Zhengzhong., Zhu, Jiahui., Wang, Yintong., Xie, Yongyong., ... & Cheng, Jinguo. (2021). Therapeutic effects of traditional Chinese medicine (Maxingshigan-Weijing Decoction) on COVID-19: An open-label randomized controlle d trial. INTEGRATIVE MEDICINE RESEARCH, 10(Suppl), 100782. |
MLA | Zeng, Congcong,et al."Therapeutic effects of traditional Chinese medicine (Maxingshigan-Weijing Decoction) on COVID-19: An open-label randomized controlle d trial".INTEGRATIVE MEDICINE RESEARCH 10.Suppl(2021):100782. |
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