Transcutaneous Electrical Nerve Stimulation in Relieving Neuropathic Pain: Basic Mechanisms and Clinical Applications

doi:10.1007/s11916-020-0846-1

科研成果详情

题名	Transcutaneous Electrical Nerve Stimulation in Relieving Neuropathic Pain: Basic Mechanisms and Clinical Applications
作者	Mokhtari, Tahmineh 1,2; Ren, Qiaoyue 1,2; Li, Nuo 3; Wang, Faguang 4; Bi, Yanzhi 1,2; Hu, Li 1,2,5
发表日期	2020-04-01
发表期刊	Current Pain and Headache Reports; 影响因子和分区
语种	英语
原始文献类型	Review
关键词	Analgesic effects Central neuropathic pain Neural mechanisms Peripheral neuropathic pain Transcutaneous electrical nerve stimulation
摘要	Purpose of Review: Transcutaneous electrical nerve stimulation (TENS) is widely used as a non-pharmacological approach for pain relief in a variety of clinical conditions. This manuscript aimed to review the basic mechanisms and clinical applications regarding the use of TENS for alleviating the peripheral (PNP) and central neuropathic pain (CNP). Recent Findings: Basic studies on animal models showed that TENS could alleviate pain by modulating neurotransmitters and receptors in the stimulation site and its upper levels, including the spinal cord, brainstem, and brain. Besides, many clinical studies have investigated the efficacy of TENS in patients with CNP (caused by spinal cord injury, stroke, or multiple sclerosis) and PNP (induced by diabetes, cancer, or herpes zoster). Most clinical trials have demonstrated the efficacy of TENS in attenuating neuropathic pain and suggested that appropriate stimulation parameters (e.g., stimulation frequency and intensity) were critical to improving the analgesic effects of TENS. However, there are some conflicting findings related to the efficacy of TENS in relieving neuropathic pain. Summary: With optimized stimulation parameters, TENS would be effective in attenuating neuropathic pain. To obtain sufficient evidence to support the use of TENS in the clinic, researchers recommended performing multicenter clinical trials with optimized TENS protocols for the treatment of various CNP and PNP.
资助项目	Institute of Psychology[KLMH2018ZG01];National Natural Science Foundation of China[31671141,31800926,31822025];Chinese Academy of Sciences[XXH13506];China Postdoctoral Science Foundation[2018M640191,Y6CX021008,Y8CX351005];
出版者	Springer
ISSN	1531-3433
EISSN	1534-3081
卷号	24 期号:4
DOI	10.1007/s11916-020-0846-1
收录类别	SCOPUS
URL	查看原文
PubMed ID	32072323
SCOPUSEID	2-s2.0-85079632982
通讯作者地址	[Bi, Yanzhi]CAS Key Laboratory of Mental Health,Institute of Psychology,Chinese Academy of Sciences,Beijing,China
Scopus学科分类	Neurology (clinical);Anesthesiology and Pain Medicine
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/184950
专题	温州医科大学
通讯作者	Bi, Yanzhi
作者单位	1.CAS Key Laboratory of Mental Health,Institute of Psychology,Chinese Academy of Sciences,Beijing,China; 2.Department of Psychology,University of Chinese Academy of Sciences,Beijing,China; 3.Radio Research Agency,Liaoning Institute of Metrology,Shenyang,China; 4.Department of Electrical & Electronics Engineering,Wenzhou Vocational & Technical College,Wenzhou,China; 5.Department of Pain Management,The State Key Clinical Specialty in Pain Medicine,The Second Affiliated Hospital of Guangzhou Medical University,Guangzhou,China
推荐引用方式 GB/T 7714	Mokhtari, Tahmineh,Ren, Qiaoyue,Li, Nuo,et al. Transcutaneous Electrical Nerve Stimulation in Relieving Neuropathic Pain: Basic Mechanisms and Clinical Applications[J]. Current Pain and Headache Reports;,2020,24(4).
APA	Mokhtari, Tahmineh, Ren, Qiaoyue, Li, Nuo, Wang, Faguang, Bi, Yanzhi, & Hu, Li. (2020). Transcutaneous Electrical Nerve Stimulation in Relieving Neuropathic Pain: Basic Mechanisms and Clinical Applications. Current Pain and Headache Reports;, 24(4).
MLA	Mokhtari, Tahmineh,et al."Transcutaneous Electrical Nerve Stimulation in Relieving Neuropathic Pain: Basic Mechanisms and Clinical Applications".Current Pain and Headache Reports; 24.4(2020).