Infrared Raman spectroscopy enables noninvasive biochemical assessment of skin tissue and the thermal stability

doi:10.1016/j.heliyon.2023.e21974

科研成果详情

题名	Infrared Raman spectroscopy enables noninvasive biochemical assessment of skin tissue and the thermal stability
作者	Wang, Xiaoyi1; Hua, Fangqi 2; Xie, Xianhai3; Wu, Yungang1; Sun, Wenxue4; Jiang, Zipei5; Zhang, Jinzhong 2; Luo, Xu6,7,8
发表日期	2023-11-01
发表期刊	Heliyon; 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Burn injury Raman spectra Skin tissue Thermal stability
其他关键词	BURN ; IDENTIFICATION ; IDENTIFY ; IR
摘要	Raman-active modes of human skin and pork belly have been studied systematically by a near-infrared Raman spectrometer with an exciting laser of 1064 nm. The main components and quantitative determination of pork belly are extracted by fitting the Raman spectra with the normalized Raman spectra of biochemical reagents such as collagen, elastin, triolein, fibronectin, fibrin, and hyaluronic acid. It demonstrates that the main components and quantity are various at different locations of pork belly, while the main components of human skin are similar to those of pig skin. In a further step, the evolution of the heating time-dependent Raman modes of isolated pig skin has been investigated for the mechanism of burnt skin. One can find that the spatial structure and main components of skin have an excellent thermal stability in the temperature range from -120 to 200 ∘C, which is confirmed by the temperature dependent Raman spectra of isolated pig skin, microporous acellular dermal matrix (MADM) as well as their corresponding biochemical reagents (collagen, elastin, triolein, etc.). These results help understand the mechanism of the living skin burnt by fire or hot water, and supplies an alternative technology for surgeons to diagnose the depth of a burn injury in time.
资助项目	Project of Flexible Talent Introduction[RXRC202101];Zhejiang Medical and Health Science and technology[2022496777];Zhejiang Medical and Health Science and technology plan[2018KY124];
出版者	CELL PRESS
ISSN	2405-8440
EISSN	2405-8440
卷号	9 期号:11
DOI	10.1016/j.heliyon.2023.e21974
页数	8
WOS类目	Multidisciplinary Sciences
WOS研究方向	Science & Technology - Other Topics
WOS记录号	WOS:001114446700001
收录类别	SCOPUS ; PUBMED ; SCIE
在线发表日期	2023-11
URL	查看原文
PubMed ID	38034814
SCOPUSEID	2-s2.0-85176443088
通讯作者地址	[Zhang, Jinzhong]Department of Wound Repair,the Quzhou Affiliated Hospital of Wenzhou Medical University,Quzhou People's Hospital,Quzhou,324000,China ; [Luo, Xu]National Key Clinical Specialty (Wound Healing),Department of Wounds and Burns,the First Affiliated Hospital of Wenzhou Medical University,Zhejiang,Wenzhou,325000,China
Scopus学科分类	Multidisciplinary
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/184665
专题	附属第一医院其他_温州医科大学附属衢州医院
通讯作者	Zhang, Jinzhong; Luo, Xu
作者单位	1.Traditional Chinese Medicine (TCM) Orthopedics & Traumatology,the First Affiliated Hospital of Wenzhou Medical University,Zhejiang,Wenzhou,325000,China; 2.Department of Wound Repair,the Quzhou Affiliated Hospital of Wenzhou Medical University,Quzhou People's Hospital,Quzhou,324000,China; 3.Department of the Trauma,the First Affiliated Hospital of Wenzhou Medical University,Zhejiang,Wenzhou,325000,China; 4.Hemodialysis Room,Department of Nephrology,the First Affiliated Hospital of Wenzhou Medical University,Zhejiang,Wenzhou,325000,China; 5.Department of Ophthalmology,the First Affiliated Hospital of Wenzhou Medical University,Zhejiang,Wenzhou,325000,China; 6.National Key Clinical Specialty (Wound Healing),Department of Wounds and Burns,the First Affiliated Hospital of Wenzhou Medical University,Zhejiang,Wenzhou,325000,China; 7.Key Laboratory of Intelligent Treatment and Life Support for Critical Diseases of Zhejiang Province,the First Affiliated Hospital of Wenzhou Medical University,Wenzhou,325000,China; 8.Zhejiang Engineering Research Center for Hospital Emergency and Process Digitization,Zhejiang,Wenzhou,325000,China
第一作者单位	附属第一医院; 第一临床医学院（信息与工程学院）、附属第一医院
通讯作者单位	温州医科大学附属衢州医院; 附属第一医院; 第一临床医学院（信息与工程学院）、附属第一医院
第一作者的第一单位	附属第一医院
推荐引用方式 GB/T 7714	Wang, Xiaoyi,Hua, Fangqi,Xie, Xianhai,et al. Infrared Raman spectroscopy enables noninvasive biochemical assessment of skin tissue and the thermal stability[J]. Heliyon;,2023,9(11).
APA	Wang, Xiaoyi., Hua, Fangqi., Xie, Xianhai., Wu, Yungang., Sun, Wenxue., ... & Luo, Xu. (2023). Infrared Raman spectroscopy enables noninvasive biochemical assessment of skin tissue and the thermal stability. Heliyon;, 9(11).
MLA	Wang, Xiaoyi,et al."Infrared Raman spectroscopy enables noninvasive biochemical assessment of skin tissue and the thermal stability".Heliyon; 9.11(2023).