题名 | Saliva biomarkers in oral disease |
作者 | |
发表日期 | 2023-08-01 |
发表期刊 | Clinica chimica acta international journal of clinical chemistry 影响因子和分区 |
语种 | 英语 |
原始文献类型 | Journal Article ; Review |
关键词 | Biomarker Diagnosis Oral disease Saliva Saliva detection |
其他关键词 | GINGIVAL CREVICULAR FLUID ; SQUAMOUS-CELL CARCINOMA ; 2-DIMENSIONAL GEL-ELECTROPHORESIS ; PRIMARY SJOGRENS-SYNDROME ; N-LINKED GLYCOPROTEINS ; PROLINE-RICH PROTEINS ; PERIODONTAL-DISEASE ; FLOW-RATE ; LIQUID-CHROMATOGRAPHY ; COLLECTION DEVICES |
摘要 | Saliva is a versatile biofluid that contains a wide variety of biomarkers reflecting both physiologic and pathophysiologic states. Saliva collection is noninvasive and highly applicable for tests requiring serial sampling. Furthermore, advances in test accuracy, sensitivity and precision for saliva has improved diagnostic performance as well as the identification of novel markers especially in oral disease processes. These include dental caries, periodontitis, oral squamous cell carcinoma (OSCC) and Sjögren's syndrome (SS). Numerous growth factors, enzymes, interleukins and cytokines have been identified and are the subject of much research investigation. This review highlights current procedures for successful determination of saliva biomarkers including preanalytical factors associated with sampling, storage and pretreatment as well as subsequent analysis. Moreover, it provides an overview of the diagnostic applications of these salivary biomarkers in common oral diseases. |
出版者 | ELSEVIER |
ISSN | 0009-8981 |
EISSN | 1873-3492 |
卷号 | 548 |
DOI | 10.1016/j.cca.2023.117503 |
页数 | 21 |
WOS类目 | Medical Laboratory Technology |
WOS研究方向 | Medical Laboratory Technology |
WOS记录号 | WOS:001052204600001 |
收录类别 | PUBMED ; SCIE ; SCOPUS |
在线发表日期 | 2023-08 |
URL | 查看原文 |
PubMed ID | 37536520 |
SCOPUSEID | 2-s2.0-85166937937 |
通讯作者地址 | [Liu, Zhenqi]Department of Cariology and Endodontics,West China Hospital of Stomatology,Sichuan University,Chengdu,610000,China |
Scopus学科分类 | Biochemistry;Clinical Biochemistry;Biochemistry (medical) |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | https://kms.wmu.edu.cn/handle/3ETUA0LF/181813 |
专题 | 仁济学院 |
通讯作者 | Liu, Zhenqi |
作者单位 | 1.Wenzhou Medical University Renji College,Wenzhou,China; 2.Department of Cariology and Endodontics,West China Hospital of Stomatology,Sichuan University,Chengdu,China |
第一作者单位 | 仁济学院 |
第一作者的第一单位 | 仁济学院 |
推荐引用方式 GB/T 7714 | Zhou, Yuehong,Liu, Zhenqi. Saliva biomarkers in oral disease[J]. Clinica chimica acta international journal of clinical chemistry,2023,548. |
APA | Zhou, Yuehong, & Liu, Zhenqi. (2023). Saliva biomarkers in oral disease. Clinica chimica acta international journal of clinical chemistry, 548. |
MLA | Zhou, Yuehong,et al."Saliva biomarkers in oral disease".Clinica chimica acta international journal of clinical chemistry 548(2023). |
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