科研成果详情

题名Saliva biomarkers in oral disease
作者
发表日期2023-08-01
发表期刊Clinica chimica acta international journal of clinical chemistry   影响因子和分区
语种英语
原始文献类型Journal Article ; Review
关键词Biomarker Diagnosis Oral disease Saliva Saliva detection
其他关键词GINGIVAL CREVICULAR FLUID ; SQUAMOUS-CELL CARCINOMA ; 2-DIMENSIONAL GEL-ELECTROPHORESIS ; PRIMARY SJOGRENS-SYNDROME ; N-LINKED GLYCOPROTEINS ; PROLINE-RICH PROTEINS ; PERIODONTAL-DISEASE ; FLOW-RATE ; LIQUID-CHROMATOGRAPHY ; COLLECTION DEVICES
摘要Saliva is a versatile biofluid that contains a wide variety of biomarkers reflecting both physiologic and pathophysiologic states. Saliva collection is noninvasive and highly applicable for tests requiring serial sampling. Furthermore, advances in test accuracy, sensitivity and precision for saliva has improved diagnostic performance as well as the identification of novel markers especially in oral disease processes. These include dental caries, periodontitis, oral squamous cell carcinoma (OSCC) and Sjögren's syndrome (SS). Numerous growth factors, enzymes, interleukins and cytokines have been identified and are the subject of much research investigation. This review highlights current procedures for successful determination of saliva biomarkers including preanalytical factors associated with sampling, storage and pretreatment as well as subsequent analysis. Moreover, it provides an overview of the diagnostic applications of these salivary biomarkers in common oral diseases.
出版者ELSEVIER
ISSN0009-8981
EISSN1873-3492
卷号548
DOI10.1016/j.cca.2023.117503
页数21
WOS类目Medical Laboratory Technology
WOS研究方向Medical Laboratory Technology
WOS记录号WOS:001052204600001
收录类别PUBMED ; SCIE ; SCOPUS
在线发表日期2023-08
URL查看原文
PubMed ID37536520
SCOPUSEID2-s2.0-85166937937
通讯作者地址[Liu, Zhenqi]Department of Cariology and Endodontics,West China Hospital of Stomatology,Sichuan University,Chengdu,610000,China
Scopus学科分类Biochemistry;Clinical Biochemistry;Biochemistry (medical)
引用统计
文献类型期刊论文
条目标识符https://kms.wmu.edu.cn/handle/3ETUA0LF/181813
专题仁济学院
通讯作者Liu, Zhenqi
作者单位
1.Wenzhou Medical University Renji College,Wenzhou,China;
2.Department of Cariology and Endodontics,West China Hospital of Stomatology,Sichuan University,Chengdu,China
第一作者单位仁济学院
第一作者的第一单位仁济学院
推荐引用方式
GB/T 7714
Zhou, Yuehong,Liu, Zhenqi. Saliva biomarkers in oral disease[J]. Clinica chimica acta international journal of clinical chemistry,2023,548.
APA Zhou, Yuehong, & Liu, Zhenqi. (2023). Saliva biomarkers in oral disease. Clinica chimica acta international journal of clinical chemistry, 548.
MLA Zhou, Yuehong,et al."Saliva biomarkers in oral disease".Clinica chimica acta international journal of clinical chemistry 548(2023).

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