Advance in topical biomaterials and mechanisms for the intervention of pressure injury

doi:10.1016/j.isci.2023.106956

科研成果详情

题名	Advance in topical biomaterials and mechanisms for the intervention of pressure injury
作者	Pan, Yingying1; Yang, Dejun 2; Zhou, Min1; Liu, Yong 2,3; Pan, Jiandan 4; Wu, Yunlong 2,5; Huang, Lijiang3; Li, Huaqiong3
发表日期	2023-06-16
发表期刊	iScience 影响因子和分区
语种	英语
原始文献类型	Journal Article ; Review
关键词	Biomaterials Health sciences Materials science Pressure sore prevention in health technology
其他关键词	FIBROBLAST-GROWTH-FACTOR ; SPINAL-CORD-INJURY ; ISCHEMIA-REPERFUSION INJURY ; ULCER DEVELOPMENT ; DOUBLE-BLIND ; MACROPHAGE POLARIZATION ; NEUTROPHIL INFILTRATION ; SUBEPIDERMAL MOISTURE ; EXTRACELLULAR-MATRIX ; STEM-CELLS
摘要	Pressure injuries (PIs) are localized tissue damage resulting from prolonged compression or shear forces on the skin or underlying tissue, or both. Different stages of PIs share common features include intense oxidative stress, abnormal inflammatory response, cell death, and subdued tissue remodeling. Despite various clinical interventions, stage 1 or stage 2 PIs are hard to monitor for the changes of skin or identify from other disease, whereas stage 3 or stage 4 PIs are challenging to heal, painful, expensive to manage, and have a negative impact on quality of life. Here, we review the underlying pathogenesis and the current advances of biochemicals in PIs. We first discuss the crucial events involved in the pathogenesis of PIs and key biochemical pathways lead to wound delay. Then, we examine the recent progress of biomaterials-assisted wound prevention and healing and their prospects.
资助项目	Wenzhou Science and Technology Bureau [Y2020200, Y20210075]; Medical and Health Technology Projects of Zhejiang province [2021KY777]; Zhejiang Provincial Natural Sci- ence Found of China [LQ23H150002]; Wenzhou Institute, University of Chinese Academy of Sciences [WIUCASQD2019002, WIUCASQD2022017, WIUCASK19003, WIUCASZZXF21005]
出版者	CELL PRESS
ISSN	2589-0042
EISSN	2589-0042
卷号	26 期号:6
DOI	10.1016/j.isci.2023.106956
页数	18
WOS类目	Multidisciplinary Sciences
WOS研究方向	Science & Technology - Other Topics
WOS记录号	WOS:001021388700001
收录类别	PUBMED ; SCIE ; SCOPUS
在线发表日期	2023-06
URL	查看原文
PubMed ID	37378311
SCOPUSEID	2-s2.0-85161305527
通讯作者地址	[Yang, Dejun]Engineering Research Center of Clinical Functional Materials and Diagnosis & Treatment Devices of Zhejiang Province,Wenzhou Institute,University of Chinese Academy of Sciences,Zhejiang,Wenzhou,325011,China ; [Liu, Yong]Engineering Research Center of Clinical Functional Materials and Diagnosis & Treatment Devices of Zhejiang Province,Wenzhou Institute,University of Chinese Academy of Sciences,Zhejiang,Wenzhou,325011,China ; [Li, Huaqiong]Joint Research Centre on Medicine,The Affiliated Xiangshan Hospital of Wenzhou Medical University,Zhejiang,Ningbo,315700,China
Scopus学科分类	Multidisciplinary
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/181241
专题	护理学院附属第二医院第二临床医学院、附属第二医院、育英儿童医院其他_附属象山医院（象山县第一人民医院）其他_附属萧山医院（杭州市萧山区第一人民医院）
通讯作者	Yang, Dejun; Liu, Yong; Li, Huaqiong
作者单位	1.School of Nursing,Wenzhou Medical University,Zhejiang,Wenzhou,325035,China; 2.Engineering Research Center of Clinical Functional Materials and Diagnosis & Treatment Devices of Zhejiang Province,Wenzhou Institute,University of Chinese Academy of Sciences,Zhejiang,Wenzhou,325011,China; 3.Joint Research Centre on Medicine,The Affiliated Xiangshan Hospital of Wenzhou Medical University,Zhejiang,Ningbo,315700,China; 4.The Second Affiliated Hospital of Wenzhou Medical University,Zhejiang,Wenzhou,325035,China; 5.School of Pharmaceutical Sciences,Xiamen University,Fujian,Xiamen,361102,China
第一作者单位	护理学院
通讯作者单位	附属萧山医院（杭州市萧山区第一人民医院）; 附属象山医院（象山县第一人民医院）
第一作者的第一单位	护理学院
推荐引用方式 GB/T 7714	Pan, Yingying,Yang, Dejun,Zhou, Min,et al. Advance in topical biomaterials and mechanisms for the intervention of pressure injury[J]. iScience,2023,26(6).
APA	Pan, Yingying., Yang, Dejun., Zhou, Min., Liu, Yong., Pan, Jiandan., ... & Li, Huaqiong. (2023). Advance in topical biomaterials and mechanisms for the intervention of pressure injury. iScience, 26(6).
MLA	Pan, Yingying,et al."Advance in topical biomaterials and mechanisms for the intervention of pressure injury".iScience 26.6(2023).