ZnP-Coated Zn-1Cu-0.1Ti Membrane with High Strength-Ductility, Antibacterial Ability, Cytocompatibility, and Osteogenesis for Biodegradable Guided Bone Regeneration Applications

doi:10.1002/adfm.202214657

科研成果详情

题名	ZnP-Coated Zn-1Cu-0.1Ti Membrane with High Strength-Ductility, Antibacterial Ability, Cytocompatibility, and Osteogenesis for Biodegradable Guided Bone Regeneration Applications
作者	Tong, Xian1,2; Han, Yue1; Zhu, Li 1; Zhou, Runqi1; Lin, Zhiqiang1; Wang, Hongning1; Huang, Shengbin1; Li, Yuncang 3; Ma, Jianfeng 1; Wen, Cuie 3; Lin, Jixing1
发表日期	2023-08
发表期刊	ADVANCED FUNCTIONAL MATERIALS 影响因子和分区
语种	英语
原始文献类型	Article ; Early Access
关键词	biodegradability guided bone regeneration membrane mechanical stability osteogenesis zinc alloys
其他关键词	IN-VITRO DEGRADATION ; MECHANICAL-PROPERTIES ; BARRIER MEMBRANES ; TITANIUM MESH ; PURE ZINC ; ALLOYS ; BEHAVIOR ; MAGNESIUM ; TISSUE ; CYTOTOXICITY
摘要	Zinc (Zn) and its alloys have recently gained research interest due to their good biosafety, biological function, biodegradability, and formability. Zinc-phosphate (ZnP) coating has been shown to improve the corrosion resistance and biocompatibility of Zn alloys. Here, a biodegradable ZnP-coating on Zn-1Cu-0.1Ti (ZCT) membrane with high strength-ductility and mechanical stability, suitable degradation rate, effective antibacterial ability, excellent in vitro and in vivo cytocompatibility, and osteogenesis is reported. The ZnP-coated ZCT exhibits high strength-ductility with a yield strength of 264 MPa, ultimate tensile strength of 312 MPa, elongation of 36.0%, and high mechanical stability before and after 30 d immersion in Hanks' and AS solutions, all of which are higher than those of ZCT. The ZnP coating shows good deformation resistance, healing effect, and bond strength with the substrate, meeting the clinical contour shaping requirements. The ZnP-coated ZCT membrane sample shows higher cell viability toward MC3T3-E1 and MG-63 cells, osteogenic and mitochondrial quality-control properties in vitro than those of the ZCT sample. Using a rat calvarial defect model, the ZnP-coated ZCT membrane shows complete biosafety and considerable osteogenesis performance. Overall, the ZnP-coated ZCT membrane is recommended as a promising biodegradable implant material for oral guided bone regeneration application.
资助项目	Australian Research Council[DP210101862];Zhejiang Public Welfare Technology Application Research Project of China[LGF22H140008];
出版者	WILEY-V C H VERLAG GMBH
ISSN	1616-301X
EISSN	1616-3028
卷号	33 期号:31
DOI	10.1002/adfm.202214657
页数	26
WOS类目	Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter
WOS研究方向	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
WOS记录号	WOS:000978253100001
收录类别	SCIE ; EI ; SCOPUS
在线发表日期	2023-04
EI入藏号	20231814041098
EI主题词	Zinc alloys
EI分类号	461.9.1 Immunology ; 531.1 Metallurgy ; 539.1 Metals Corrosion ; 539.2 Corrosion Protection ; 542.3 Titanium and Alloys ; 544.2 Copper Alloys ; 546.3 Zinc and Alloys ; 801.2 Biochemistry ; 802.2 Chemical Reactions ; 813.2 Coating Materials ; 951 Materials Science
URL	查看原文
SCOPUSEID	2-s2.0-85154051501
自科自定义期刊分类	T3(A)类
通讯作者地址	[Ma, Jianfeng]Institute of Stomatology,School and Hospital of Stomatology,Wenzhou Medical University,Wenzhou,325027,China ; [Lin, Jixing]Institute of Stomatology,School and Hospital of Stomatology,Wenzhou Medical University,Wenzhou,325027,China ; [Wen, Cuie]School of Engineering,RMIT University,Melbourne,3001,Australia
Scopus学科分类	Electronic, Optical and Magnetic Materials;Chemistry (all);Biomaterials;Materials Science (all);Condensed Matter Physics;Electrochemistry
TOP期刊	TOP期刊
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/180087
专题	口腔医学院、附属口腔医院_口腔医学研究所
通讯作者	Ma, Jianfeng; Wen, Cuie; Lin, Jixing
作者单位	1.Institute of Stomatology,School and Hospital of Stomatology,Wenzhou Medical University,Wenzhou,325027,China; 2.School of Materials Science and Engineering,Xiangtan University,Xiangtan,411105,China; 3.School of Engineering,RMIT University,Melbourne,3001,Australia
第一作者单位	口腔医学院、附属口腔医院_口腔医学研究所
通讯作者单位	口腔医学院、附属口腔医院_口腔医学研究所
第一作者的第一单位	口腔医学院、附属口腔医院_口腔医学研究所
推荐引用方式 GB/T 7714	Tong, Xian,Han, Yue,Zhu, Li,et al. ZnP-Coated Zn-1Cu-0.1Ti Membrane with High Strength-Ductility, Antibacterial Ability, Cytocompatibility, and Osteogenesis for Biodegradable Guided Bone Regeneration Applications[J]. ADVANCED FUNCTIONAL MATERIALS,2023,33(31).
APA	Tong, Xian., Han, Yue., Zhu, Li., Zhou, Runqi., Lin, Zhiqiang., ... & Lin, Jixing. (2023). ZnP-Coated Zn-1Cu-0.1Ti Membrane with High Strength-Ductility, Antibacterial Ability, Cytocompatibility, and Osteogenesis for Biodegradable Guided Bone Regeneration Applications. ADVANCED FUNCTIONAL MATERIALS, 33(31).
MLA	Tong, Xian,et al."ZnP-Coated Zn-1Cu-0.1Ti Membrane with High Strength-Ductility, Antibacterial Ability, Cytocompatibility, and Osteogenesis for Biodegradable Guided Bone Regeneration Applications".ADVANCED FUNCTIONAL MATERIALS 33.31(2023).