Development of a Novel Nomogram Incorporating Red Blood Cell Distribution Width-Albumin Ratio for the Prediction of 30-day Mortality in Acute Pancreatitis Patients

doi:10.1155/2022/1573931

科研成果详情

题名	Development of a Novel Nomogram Incorporating Red Blood Cell Distribution Width-Albumin Ratio for the Prediction of 30-day Mortality in Acute Pancreatitis Patients
作者	Pan, Li-na1; Pan, Shen-ao 2; Lei, Bu-huai3; Hong, Guang-liang3; Chen, Kun-wei3
发表日期	2022-11-28
发表期刊	EMERGENCY MEDICINE INTERNATIONAL 影响因子和分区
语种	英语
原始文献类型	Article
其他关键词	ATRIAL-FIBRILLATION
摘要	Purpose. The available nomograms used to predict acute pancreatitis (AP) are not comprehensive. We sought to investigate the effect of red blood cell distribution width (RDW)-albumin ratio (RA) on prognosis of patients with AP and develop a new nomogram to identify AP patients at high risk for mortality. Methods. We used data from the Medical Information Mart for Intensive Care IV version 2.0 (MIMIC-IV v2.0). A total of 487 patients with acute pancreatitis were included. Patients enrolled in the study were randomly assigned to the training set and validation set at a 7 : 3 ratio. According to the 30-day mortality rate, the data were divided into a survival group and a death group. Multivariate logistic regression was used to establish a prognostic nomogram for predicting the 30-day mortality in AP patients. The area under the receiver operating characteristic curve (AUC), calibration curve, the net reclassification improvement (NRI), the integrated discrimination improvement (IDI), and a decision curve analysis (DCA) are used to verify the overall performance of the model. Results. Among 487 patients, 54 patients died (11.1%). 338 patients were assigned to the training cohort and 149 were assigned to the validation cohort. The multivariate analysis results showed that RA, age, heart rate, temperature, AST/ALT, BUN, hemoglobin, potassium, and bilirubin were independent risk factors. The prediction performance of the newly established nomogram was better than those of other common scoring systems (including SOFA, OASIS, and APSIII). The nomogram suggests that RA (OR = 1.706, 95% CI: 1.367-2.185) is the most significant laboratory test indicator influencing prognosis. Conclusion. The new nomogram incorporating RA performed well in predicting AP short-term mortality. A prospective study with a larger sample is needed to validate our findings.
资助项目	National Key R&D Program of China; Science and Technology Plan Project of Wenzhou; [2021YFC3002205]; [2021Y1205]
出版者	HINDAWI LTD
出版地	LONDON
ISSN	2090-2840
EISSN	2090-2859
卷号	2022 页码:1573931
DOI	10.1155/2022/1573931
页数	10
WOS类目	Emergency Medicine
WOS研究方向	Emergency Medicine
WOS记录号	WOS:000895999200001
收录类别	SCIE ; PUBMED
URL	查看原文
PubMed ID	36478954
通讯作者地址	[Chen, Kun-wei]Wenzhou Med Univ, Affiliated Hosp 1, Dept Emergency, Wenzhou 325000, Peoples R China.
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/172018
专题	附属第一医院_麻醉科附属第一医院_急诊科第二临床医学院，附属第二医院、育英儿童医院
通讯作者	Chen, Kun-wei
作者单位	1.Wenzhou Med Univ, Affiliated Hosp 1, Dept Anesthesiol, Wenzhou 325000, Peoples R China; 2.Wenzhou Med Univ, Clin Med Coll 2, Wenzhou 325035, Peoples R China; 3.Wenzhou Med Univ, Affiliated Hosp 1, Dept Emergency, Wenzhou 325000, Peoples R China
第一作者单位	附属第一医院_麻醉科
通讯作者单位	附属第一医院_急诊科
第一作者的第一单位	附属第一医院_麻醉科
推荐引用方式 GB/T 7714	Pan, Li-na,Pan, Shen-ao,Lei, Bu-huai,et al. Development of a Novel Nomogram Incorporating Red Blood Cell Distribution Width-Albumin Ratio for the Prediction of 30-day Mortality in Acute Pancreatitis Patients[J]. EMERGENCY MEDICINE INTERNATIONAL,2022,2022:1573931.
APA	Pan, Li-na, Pan, Shen-ao, Lei, Bu-huai, Hong, Guang-liang, & Chen, Kun-wei. (2022). Development of a Novel Nomogram Incorporating Red Blood Cell Distribution Width-Albumin Ratio for the Prediction of 30-day Mortality in Acute Pancreatitis Patients. EMERGENCY MEDICINE INTERNATIONAL, 2022, 1573931.
MLA	Pan, Li-na,et al."Development of a Novel Nomogram Incorporating Red Blood Cell Distribution Width-Albumin Ratio for the Prediction of 30-day Mortality in Acute Pancreatitis Patients".EMERGENCY MEDICINE INTERNATIONAL 2022(2022):1573931.