Scoring model to predict outcome in critically ill cirrhotic patients with acute respiratory failure: comparison with MELD scoring models and CLIF-SOFA score

doi:10.1080/17474124.2017.1338948

科研成果详情

题名	Scoring model to predict outcome in critically ill cirrhotic patients with acute respiratory failure: comparison with MELD scoring models and CLIF-SOFA score
作者	Zhou, Xiao Dong 1; Chen, Qin Fen 2; Zhang, Ming Chun 1; Van Poucke, Sven 3; Liu, Wen Yue 4; Lu, Yao5; Shi, Ke Qing 6,7; Huang, Wei Jian 1; Zheng, Ming Hua 6,7
发表日期	2017-12-31
发表期刊	EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Critically ill cirrhotic acute respiratory failure CLIF-SOFA MELD prognosis
其他关键词	CHRONIC LIVER-FAILURE ; SERUM SODIUM ; INTENSIVE-CARE ; DISEASE SCORE ; MORTALITY ; SYSTEMS ; DYSFUNCTION ; VALIDATION ; BILIRUBIN ; RATIO
摘要	Background: Critically ill cirrhotic patients have a high mortality, particularly with concomitant respiratory failure on admission. There are no specific models in use for mortality risk assessment in critically ill cirrhotic patients with acute respiratory failure (CICRF). The aim is to develop a risk prediction model specific to CICRF in order to quantify the severity of illness.Methods: We analyzed 949 CICRF patients extracted from the MIMIC-III database. The novel model (ARF-CLIF-SOFA) was developed from the CLIF-SOFA score. Cox regression analysis and AUROC were implemented to test the predictive accuracy, compared with existing scores including the CLIF-SOFA score and MELD-related scores.Results: ARF-CLIF-SOFA contains PaO2/FiO(2) ratio, lactate, MAP, vasopressor therapy, bilirubin and creatinine (1 point each; score range: 0-6). Based on our patient cohort, the ARF-CLIF-SOFA score had good predictive accuracy for predicting the 30-, 90-day and 1-year mortality (AUROC=0.767 at 30-day, 0.768 at 90-day, 0.765 at 1-year, respectively). Additionally, the performance of the ARF-CLIF-SOFA is superior to existing scores (all P<0.001).Conclusion: The ARF-CLIF-SOFA score can be considered a CICRF specific score with a better predictive accuracy compared to the existing scores.
资助项目	National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81500665]; Scientific Research Foundation of Wenzhou [Y20160223]; High Level Creative Talents from Department of Public Health in Zhejiang Province; Project of New Century 551 Talent Nurturing in Wenzhou
出版者	TAYLOR & FRANCIS LTD
出版地	ABINGDON
ISSN	1747-4124
EISSN	1747-4132
卷号	11 期号:9 页码:857-864
DOI	10.1080/17474124.2017.1338948
页数	8
WOS类目	Gastroenterology & Hepatology
WOS研究方向	Gastroenterology & Hepatology
WOS记录号	WOS:000407140700009
收录类别	SCIE ; SCOPUS ; PUBMED
URL	查看原文
PubMed ID	28597703
SCOPUSEID	2-s2.0-85020532788
通讯作者地址	[Huang, Wei Jian]Department of Cardiovascular Medicine,the Heart Center,the First Affiliated Hospital of Wenzhou Medical University,No. 2 Fuxue Lane,Wenzhou,325000,China
Scopus学科分类	Hepatology;Gastroenterology
引用统计	被引频次：4[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/17069
专题	附属第一医院附属第一医院_感染内科
通讯作者	Huang, Wei Jian
作者单位	1.Department of Cardiovascular Medicine,the Heart Center,the First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China; 2.Department of Gastroenterology,the First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China; 3.Department of Anesthesiology,Intensive Care,Emergency Medicine and Pain Therapy,Ziekenhuis Oost-Limburg,Genk,Belgium; 4.Department of Endocrinology,the First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China; 5.Department of Respiratory and Critical Care Medicine,the First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China; 6.Department of Hepatology,Liver Research Center,the First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China; 7.Institute of Hepatology,Wenzhou Medical University,Wenzhou,China
第一作者单位	附属第一医院
通讯作者单位	附属第一医院
第一作者的第一单位	附属第一医院
推荐引用方式 GB/T 7714	Zhou, Xiao Dong,Chen, Qin Fen,Zhang, Ming Chun,et al. Scoring model to predict outcome in critically ill cirrhotic patients with acute respiratory failure: comparison with MELD scoring models and CLIF-SOFA score[J]. EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY,2017,11(9):857-864.
APA	Zhou, Xiao Dong., Chen, Qin Fen., Zhang, Ming Chun., Van Poucke, Sven., Liu, Wen Yue., ... & Zheng, Ming Hua. (2017). Scoring model to predict outcome in critically ill cirrhotic patients with acute respiratory failure: comparison with MELD scoring models and CLIF-SOFA score. EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, 11(9), 857-864.
MLA	Zhou, Xiao Dong,et al."Scoring model to predict outcome in critically ill cirrhotic patients with acute respiratory failure: comparison with MELD scoring models and CLIF-SOFA score".EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY 11.9(2017):857-864.