Nomogram of intra-abdominal infection after surgery in patients with gastric cancer: A retrospective study.

doi:10.3389/fonc.2022.982807

科研成果详情

题名	Nomogram of intra-abdominal infection after surgery in patients with gastric cancer: A retrospective study.
作者	Zhang, Yue1,2; Wang, Zhengfei3; Basharat, Zarrin 4; Hu, Mengjun 5; Hong, Wandong6; Chen, Xiangjian2
发表日期	2022-10-03
发表期刊	Frontiers in oncology 影响因子和分区
语种	英语
原始文献类型	Article
关键词	gastric cancer intra-abdominal infection nomogram postoperative complications receiver operating characteristic curve surgery
其他关键词	POSTOPERATIVE COMPLICATIONS ; RADICAL GASTRECTOMY ; MORTALITY ; MORBIDITY ; METAANALYSIS ; SPLENECTOMY ; DIAGNOSIS ; OUTCOMES ; INDEX
摘要	Surgical resection is still the primary way to treat gastric cancer. Therefore, postoperative complications such as IAI (intra-abdominal infection) are major problems that front-line clinical workers should pay special attention to. This article was to build and validate IAI's RF (regression function) model. Furthermore, it analyzed the prognosis in patients with IAI after surgery for stomach cancer. The above two points are our advantages, which were not involved in previous studies., The data of this study was divided into two parts, the training data set and the validation data set. The training data for this article were from the patients treated surgically with gastric cancer in our center from December 2015 to February 2017. We examined IAI's morbidity, etiological characteristics, and prognosis in the training data set. Univariate and multivariate logistic regression analyses were used to screen risk factors, establish an RF model and create a nomogram. Data from January to March 2021 were used to validate the accuracy of the RF model., The incidence of IAI was 7.2%. The independent risk factors for IAI were hypertension (Odds Ratio [OR] = 3.408, P = 0.001), history of abdominal surgery (OR = 2.609, P = 0.041), combined organ excision (OR = 4.123, P = 0.010), and operation time ≥240 min (OR = 3.091, P = 0.005). In the training data set and validation data set, the area under the ROC curve of IAI predicted by the RF model was 0.745 ± 0.048 (P<0.001) and 0.736 ± 0.069 (P=0.003), respectively. In addition, IAI significantly extended the length of hospital stay but had little impact on survival., Patients with hypertension, combined organ excision, a history of abdominal surgery, and a surgical duration of 240 min or more are prone to IAI, and the RF model may help to identify them.
出版者	FRONTIERS MEDIA SA
出版地	LAUSANNE
ISSN	2234-943X
卷号	12 页码:982807
DOI	10.3389/fonc.2022.982807
页数	12
WOS类目	Oncology
WOS研究方向	Oncology
WOS记录号	WOS:000871301500001
收录类别	PUBMED ; SCIE ; SCOPUS
URL	查看原文
PubMed ID	36263227
SCOPUSEID	2-s2.0-85139951962
通讯作者地址	[Chen, Xiangjian]Department of Gastrointestinal Surgery,the First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China ; [Hu, Mengjun]Department of Pathology,Zhuji Affiliated Hospital of Wenzhou Medical University,Shaoxing,China ; [Hong, Wandong]Department of Gastroenterology and Hepatology,the First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China
Scopus学科分类	Oncology;Cancer Research
引用统计	被引频次[WOS]：0 [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/166965
专题	附属第一医院其他_附属诸暨医院（诸暨市人民医院）其他_温州医科大学附属衢州医院
通讯作者	Hu, Mengjun; Hong, Wandong; Chen, Xiangjian
作者单位	1.Department of Otolaryngology,Wenzhou People’s Hospital,Wenzhou,China; 2.Department of Gastrointestinal Surgery,the First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China; 3.Department of Hepato-biliary Surgery,The Quzhou Affiliated Hospital of Wenzhou Medical University,Quzhou People’s Hospital,Quzhou,China; 4.Jamil-ur-Rahman Center for Genome Research,Dr. Panjwani Center for Molecular Medicine and Drug Research,International Center for Chemical and Biological Sciences,University of Karachi,Karachi,Pakistan; 5.Department of Pathology,Zhuji Affiliated Hospital of Wenzhou Medical University,Shaoxing,China; 6.Department of Gastroenterology and Hepatology,the First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China
第一作者单位	附属第一医院; 第一临床医学院（信息与工程学院）、附属第一医院
通讯作者单位	附属第一医院; 第一临床医学院（信息与工程学院）、附属第一医院; 温州医科大学
推荐引用方式 GB/T 7714	Zhang, Yue,Wang, Zhengfei,Basharat, Zarrin,et al. Nomogram of intra-abdominal infection after surgery in patients with gastric cancer: A retrospective study.[J]. Frontiers in oncology,2022,12:982807.
APA	Zhang, Yue, Wang, Zhengfei, Basharat, Zarrin, Hu, Mengjun, Hong, Wandong, & Chen, Xiangjian. (2022). Nomogram of intra-abdominal infection after surgery in patients with gastric cancer: A retrospective study.. Frontiers in oncology, 12, 982807.
MLA	Zhang, Yue,et al."Nomogram of intra-abdominal infection after surgery in patients with gastric cancer: A retrospective study.".Frontiers in oncology 12(2022):982807.