Effect of BDE-209 on glutathione system in Carassius auratus

doi:10.1016/j.etap.2011.03.004

科研成果详情

题名	Effect of BDE-209 on glutathione system in Carassius auratus
作者	Zhao, Aijun 2; Liu, Huanqiang 2; Zhang, Aina2; Wang, Xuedong 1,2; Zhang, Hongqin1; Wang, Huili1
发表日期	2011-07
发表期刊	ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Glutathione Oxidative stress BDE-209 exposure Carassius auratus
其他关键词	DECABROMODIPHENYL ETHER BDE-209 ; POLYBROMINATED DIPHENYL ETHERS ; SPRAGUE-DAWLEY RATS ; DEBROMINATION ; EXPOSURE ; SELENIUM ; TROUT ; LIVER
摘要	In this study, the oxidative stress induced by deca-polybromodiphenyl ether (BDE-209) was investigated in livers of Carassius auratus. Six groups of fish were exposed to blank and 0, 0.004, 0.04, 0.4, 4 mu M BDE-209 (in 0.1% DMSO) for 1, 4, 7, 10, 13 d, respectively. The following oxidative stress markers were analyzed: reduced glutathione (GSH), glutathione reductase (GR), glutathione peroxidases (GPx) and glutathione S-transferases (GSTs). No significant difference was observed in the content of GSH over the whole period of exposure (p > 0.05). Increases in hepatic GR and GPx activities were in concomitant with the decrease in GST activity. GR activity was induced after 1 d exposure, while GPx activity reached maximum at 4 d after exposure to 0.04 mu M BDE-209 and GST activity was significantly inhibited at 7-13 d in all the treatment groups (0.004-4 mu M group). (C) 2011 Elsevier B.V. All rights reserved.
资助项目	Natural Science Foundation of Zhejiang ProvinceNatural Science Foundation of Zhejiang Province [Y5100333]; Wenzhou Science and Technology Bureau [H20100053, H20100054]; Analyzing and Testing Foundation of Zhejiang Province [2009F70045]
出版者	ELSEVIER
出版地	AMSTERDAM
ISSN	1382-6689
EISSN	1872-7077
卷号	32 期号:1 页码:35-39
DOI	10.1016/j.etap.2011.03.004
页数	5
WOS类目	Environmental Sciences ; Pharmacology & Pharmacy ; Toxicology
WOS研究方向	Environmental Sciences & Ecology ; Pharmacology & Pharmacy ; Toxicology
WOS记录号	WOS:000292432400005
收录类别	SCIE ; PUBMED ; SCOPUS
URL	查看原文
PubMed ID	21787727
SCOPUSEID	2-s2.0-79957816862
通讯作者地址	[Wang, Xuedong]Wenzhou Med Coll, Sch Life Sci, Wenzhou 325035, Peoples R China.
引用统计	被引频次：27[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/14597
专题	检验医学院（生命科学学院、生物学实验教学中心）仁济学院_环境与公共卫生学部
通讯作者	Wang, Xuedong
作者单位	1.Wenzhou Med Coll, Sch Life Sci, Wenzhou 325035, Peoples R China; 2.Wenzhou Med Coll, Sch Environm Sci & Publ Hlth, Wenzhou 325035, Peoples R China
第一作者单位	环境与公共卫生学部
通讯作者单位	检验医学院（生命科学学院、生物学实验教学中心）
第一作者的第一单位	环境与公共卫生学部
推荐引用方式 GB/T 7714	Zhao, Aijun,Liu, Huanqiang,Zhang, Aina,et al. Effect of BDE-209 on glutathione system in Carassius auratus[J]. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,2011,32(1):35-39.
APA	Zhao, Aijun, Liu, Huanqiang, Zhang, Aina, Wang, Xuedong, Zhang, Hongqin, & Wang, Huili. (2011). Effect of BDE-209 on glutathione system in Carassius auratus. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 32(1), 35-39.
MLA	Zhao, Aijun,et al."Effect of BDE-209 on glutathione system in Carassius auratus".ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY 32.1(2011):35-39.