Protective effect of sulfated Achyranthes bidentata polysaccharides on streptozotocin-induced oxidative stress in rats

doi:10.1016/j.carbpol.2008.08.003

科研成果详情

题名	Protective effect of sulfated Achyranthes bidentata polysaccharides on streptozotocin-induced oxidative stress in rats
作者	Xue, Shengxia; Chen, Xiaoming; Lu, Jianxin; Jin, Liqin
发表日期	2009-02-11
发表期刊	CARBOHYDRATE POLYMERS 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Achyranthes bidentata polysaccharides Sulfate Free radical Antioxidant Diabetes Oxidative stress
其他关键词	ENZYME GENE-EXPRESSION ; ANTIOXIDANT ACTIVITY ; PANCREATIC-ISLETS ; DIABETIC-RATS ; IN-VIVO ; DERIVATIVES ; COMPLICATIONS
摘要	Sulfated Achyranthes bidentata polysaccharide (SAbP) is derived from traditional Chinese herbal medicine A. bidentata polysaccharide (AbP) by chemical modification. The present Study was designed to determine the possible protective effect of SAbP against oxidative damage in streptozotocin (STZ)-treated diabetic rats. Results showed SAbP significantly reduced blood glucose level and malondialdehyde (MDA) concentration in diabetic rats. The activities of GPx and SOD were increased in diabetic rats. But the effects of AbP on blood glucose, MDA concentration and antioxidant enzymes activities are not obvious as SAW Therefore, we Postulate that SAW has a better protective effect in diabetes than AbP and this may be attributed to its antioxidative potential. (C) 2008 Published by Elsevier Ltd.
出版者	ELSEVIER SCI LTD
出版地	OXFORD
ISSN	0144-8617
EISSN	1879-1344
卷号	75 期号:3 页码:415-419
DOI	10.1016/j.carbpol.2008.08.003
页数	45
WOS类目	Chemistry, Applied ; Chemistry, Organic ; Polymer Science
WOS研究方向	Chemistry ; Polymer Science
WOS记录号	WOS:000262772300008
收录类别	SCIE ; EI ; SCOPUS
EI入藏号	20085011783533
EI主题词	Antioxidants
URL	查看原文
SCOPUSEID	2-s2.0-57349086200
通讯作者地址	[Jin, Liqin]Wenzhou Med Coll, Inst Cellular & Mol Med, Zhejiang Prov Key Lab Med Genet, Wenzhou 325035, Zhejiang, Peoples R China.
TOP期刊	TOP期刊
引用统计	被引频次：62[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/12752
专题	检验医学院（生命科学学院、生物学实验教学中心）_细胞与分子生物医学研究所
通讯作者	Jin, Liqin
作者单位	Wenzhou Med Coll, Inst Cellular & Mol Med, Zhejiang Prov Key Lab Med Genet, Wenzhou 325035, Zhejiang, Peoples R China
第一作者单位	检验医学院（生命科学学院、生物学实验教学中心）_细胞与分子生物医学研究所
通讯作者单位	检验医学院（生命科学学院、生物学实验教学中心）_细胞与分子生物医学研究所
第一作者的第一单位	检验医学院（生命科学学院、生物学实验教学中心）_细胞与分子生物医学研究所
推荐引用方式 GB/T 7714	Xue, Shengxia,Chen, Xiaoming,Lu, Jianxin,et al. Protective effect of sulfated Achyranthes bidentata polysaccharides on streptozotocin-induced oxidative stress in rats[J]. CARBOHYDRATE POLYMERS,2009,75(3):415-419.
APA	Xue, Shengxia, Chen, Xiaoming, Lu, Jianxin, & Jin, Liqin. (2009). Protective effect of sulfated Achyranthes bidentata polysaccharides on streptozotocin-induced oxidative stress in rats. CARBOHYDRATE POLYMERS, 75(3), 415-419.
MLA	Xue, Shengxia,et al."Protective effect of sulfated Achyranthes bidentata polysaccharides on streptozotocin-induced oxidative stress in rats".CARBOHYDRATE POLYMERS 75.3(2009):415-419.