科研成果详情

题名Chaos enhanced grey wolf optimization wrapped ELM for diagnosis of paraquat-poisoned patients
作者
发表期刊COMPUTATIONAL BIOLOGY AND CHEMISTRY   影响因子和分区
语种英语
原始文献类型Article
关键词Diagnosis Paraquat Chaos Grey wolf optimization Extreme learning machine
其他关键词FEATURE-SELECTION ; CLASSIFICATION ; ALGORITHM ; CLASSIFIERS
摘要Paraquat (PQ) poisoning seriously harms the health of humanity. An effective diagnostic method for paraquat poisoned patients is a crucial concern. Nevertheless, it's difficult to identify the patients with low intake of PQ or delayed treatment. Here, a new efficient diagnostic approach to integrate machine learning and gas chromatography-mass spectrometry (GC-MS), named GEE, is proposed to identify the PQ poisoned patients. First, GC-MS provides the original data that efficiently identified the paraquat-poisoned patients. According to the high dimensionality of the original data, in the second stage, the chaos enhanced grey wolf optimization (EGWO) is adopted to search the optimal feature sets to improve the accuracy of identification. Finally, the extreme learning machine (ELM) is used to identify the PQ poisoned patients. To efficiently evaluate the proposed method, four measures were used in our experiments and comparisons were made with six other methods. The PQ-poisoned patients and robust volunteers can be well identified by GEE and the values of AUC, accuracy, sensitivity and specificity were 95.14%, 93.89%, 94.44% and 95.83%, respectively. Our experimental results demonstrated that GEE had better performance and might serve as a novel candidate diagnosis of PQ-poisoned patients.
资助项目Science and Technology Plan Project of Wenzhou, China [ZG2017019]; Science and Technology Committee of Shanghai Municipality of China [KF1405]; Zhejiang Provincial Natural Science Foundation of ChinaNatural Science Foundation of Zhejiang Province [LY17F020012, LY14H230001, LY14F020035]; Guangdong Natural Science FoundationNational Natural Science Foundation of Guangdong Province [2018A030313339]; MOE (Ministry of Education in China) Youth Fund Project of Humanities and Social Sciences [17YJCZH261]; Characteristic Innovation Projects of Universities in Guangdong [2017GICTSCX063]; Special Innovation Project of Guangdong Education Department [2017GKTSCX063]; Special Funds for the Cultivation of Scientific, Technological Innovation for College Students in Guangdong [pdjh2018b0861]; 13th Five-Year Plan Project of Philosophy and Social Sciences in Shenzhen [SZ2018D017]
出版者ELSEVIER SCI LTD
出版地OXFORD
ISSN1476-9271
EISSN1476-928X
卷号78页码:481-490
DOI10.1016/j.compbiolchem.2018.11.017
页数41
WOS类目Biology ; Computer Science, Interdisciplinary Applications
WOS研究方向Life Sciences & Biomedicine - Other Topics ; Computer Science
WOS记录号WOS:000459524900051
收录类别SCIE ; EI ; SCOPUS ; PUBMED
发表日期2019-02
EI入藏号20184806160756
EI主题词Diagnosis
URL查看原文
Pubmed记录号30501982
Scopus记录号2-s2.0-85057279588
ESI热点论文2021-01
ESI高被引论文2020-01 ; 2020-09 ; 2020-11 ; 2021-01 ; 2021-03 ; 2021-05 ; 2021-07 ; 2021-09 ; 2021-11 ; 2022-01 ; 2022-03 ; 2022-07 ; 2022-09 ; 2022-11 ; 2023-01 ; 2023-03 ; 2023-05 ; 2023-07 ; 2023-09 ; 2023-11 ; 2024-01 ; 2024-03 ; 2024-05
引用统计
被引频次:260[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符https://kms.wmu.edu.cn/handle/3ETUA0LF/10603
专题药学院(分析测试中心)
附属第一医院_药学部药学部
通讯作者Chen, Huiling; Hu, Lufeng
作者单位
1.Shenzhen Inst Informat Technol, Sch Digital Media, Shenzhen 518172, Peoples R China;
2.Wenzhou Mingcheng Construct Investment Grp Co Ltd, Wenzhou, Peoples R China;
3.Wenzhou Univ, Coll Phys & Elect Informat Engn, Wenzhou 325035, Peoples R China;
4.Chinese Acad Med Sci, Shenzhen Hosp, Canc Hosp, Shenzhen 518000, Peoples R China;
5.Wenzhou Med Univ, Analyt & Testing Ctr, Wenzhou 325000, Peoples R China;
6.Shenzhen Inst Informat Technol, Sch Digital Media, Shenzhen 518172, Peoples R China;
7.Wenzhou Univ, Coll Phys & Elect Informat Engn, Wenzhou 325035, Peoples R China;
8.Wenzhou Med Univ, Affiliated Hosp 1, Dept Pharm, Nanbaixiang St, Wenzhou City 325000, Peoples R China
通讯作者单位附属第一医院;  药学部药学部
推荐引用方式
GB/T 7714
Zhao, Xuehua,Zhang, Xiang,Cai, Zhennao,et al. Chaos enhanced grey wolf optimization wrapped ELM for diagnosis of paraquat-poisoned patients[J]. COMPUTATIONAL BIOLOGY AND CHEMISTRY,2019,78:481-490.
APA Zhao, Xuehua., Zhang, Xiang., Cai, Zhennao., Tian, Xin., Wang, Xianqin., ... & Hu, Lufeng. (2019). Chaos enhanced grey wolf optimization wrapped ELM for diagnosis of paraquat-poisoned patients. COMPUTATIONAL BIOLOGY AND CHEMISTRY, 78, 481-490.
MLA Zhao, Xuehua,et al."Chaos enhanced grey wolf optimization wrapped ELM for diagnosis of paraquat-poisoned patients".COMPUTATIONAL BIOLOGY AND CHEMISTRY 78(2019):481-490.

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