Evening exercise is associated with lower odds of visual field progression in Chinese patients with primary open angle glaucoma

doi:10.1186/s40662-020-0175-9

科研成果详情

题名	Evening exercise is associated with lower odds of visual field progression in Chinese patients with primary open angle glaucoma
作者	Pan, Xiafei 1,2; Xu, Kai 3; Wang, Xin2,4; Chen, Guofu 2,4; Cheng, Huanhuan 2,4; Liu, Alice Jia 2,4; Hou, Laurence Tang 5; Zhong, Lin 2,4; Chen, Jie2; Liang, Yuanbo2,4
发表日期	2020-03-01
发表期刊	EYE AND VISION 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Glaucoma Exercise habits Visual field progression
其他关键词	INTRAOCULAR-PRESSURE ; PHYSICAL-ACTIVITY ; CARDIOVASCULAR-DISEASES ; VASCULAR WALL ; DEPRESSION ; TIME ; INTENSITY ; RESPONSES ; MARKERS ; INJURY
摘要	Background Exercise is widely known to lower intraocular pressure and increase ocular blood flow, which may be beneficial for glaucoma management. However, there are few studies that have reported on the relationship between exercise and glaucoma progression. The aim of our study was to investigate the exercise habits of those with primary open angle glaucoma (POAG) and its association with the progression of visual field (VF) loss. Methods Daily physical activity (PA) was monitored by an accelerometer (ActiGraph wGT3x-BT) which patients wore for more than 10 h of being awake on their right wrists for 1 week. Results Seventy-one non-progressive and 27 progressive patients were enrolled in the study. 24-h moderate to vigorous physical activity (MVPA) exercise showed that POAG patients had similar variation trends consisting of 3 wave peaks and 2 wave hollows. Minutes spent in MVPA was 19.89 +/- 15.81 and 21.62 +/- 15.10 during 07:00-09:00 h (p = 0.204), 15.40 +/- 14.49 and 15.67 +/- 12.43 during 15:00-17:00 h (p = 0.822) and 17.26 +/- 21.11 and 11.42 +/- 11.58 during 18:00-20:00 h (p = 0.001) in the non-progressive and progressive group, respectively. Univariate analysis indicated that 10 min of MVPA (18:00-20:00 h) [odds ratio, OR (95% CI) = 0.82 (0.73, 0.92)], average mean arterial pressure [OR (95% CI) = 0.96 (0.94, 0.98)], age [OR (95% CI) = 1.06 (1.03, 1.08)], male [OR (95% CI) = 0.67 (0.48, 0.96)], spherical equivalent [OR (95% CI) = 1.14 (1.07, 1.22)] and IOP-lowering medications [OR (95% CI) = 1.54 (1.16, 2.05)] were significantly correlated with having progressive VF damage. Multivariable analysis showed that 10 min of MVPA (18:00-20:00 h) [OR (95% CI) = 0.85 (0.75, 0.97)] was associated with progressive VF loss even after adjusting for other risk factors. Conclusions Evening exercise may lower the odds of VF progression, suggesting that exercise habits possibly play an important role in glaucoma progression.
资助项目	Wenzhou Medical University Research Fund [QTJ13009]; Zhejiang Province Health Innovation Talents Project [2016025]; Key Discipline of the Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University Fund [ZDZK201808]; Innovation Research Project of the Eye Hospital of Wenzhou Medical University [YNCX201308]
出版者	BMC
出版地	LONDON
ISSN	2326-0254
卷号	7 期号:1 页码:24-31
DOI	10.1186/s40662-020-0175-9
页数	8
WOS类目	Ophthalmology
WOS研究方向	Ophthalmology
WOS记录号	WOS:000517586600001
收录类别	SCIE ; CSCD ; SCOPUS ; PUBMED
学科领域	医药、卫生
URL	查看原文
CSCD记录号	CSCD:7132078
PubMed ID	32140501
SCOPUSEID	2-s2.0-85107314126
通讯作者地址	[Chen, Jie]School of Ophthalmology and Optometry,Eye Hospital,Wenzhou Medical University,No. 270, Xue Yuan Xi Road, Zhejiang,Wenzhou,3250027,China ; [Liang, Yuanbo]School of Ophthalmology and Optometry,Eye Hospital,Wenzhou Medical University,No. 270, Xue Yuan Xi Road, Zhejiang,Wenzhou,3250027,China
Scopus学科分类	Health Professions (miscellaneous);Ophthalmology
引用统计	被引频次：3[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/9905
专题	眼视光学院（生物医学工程学院）、附属眼视光医院眼视光学院（生物医学工程学院）、附属眼视光医院_杭州院区_青光眼专科
通讯作者	Chen, Jie; Liang, Yuanbo
作者单位	1.Department of Ophthalmology,Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation,Sun Yat-sen Memorial Hospital,Sun Yat-sen University,Guangzhou,China; 2.School of Ophthalmology and Optometry,Eye Hospital,Wenzhou Medical University,No. 270, Xue Yuan Xi Road, Zhejiang,Wenzhou,3250027,China; 3.Nanjing Sport Institute,No.8 Linggusi Road, Jiangsu,Nanjing,China; 4.Glaucoma Institute,Wenzhou Medical University,Zhejiang,Wenzhou,China; 5.Johns Hopkins University School of Medicine,Baltimore,21205,United States
第一作者单位	眼视光学院（生物医学工程学院）、附属眼视光医院
通讯作者单位	眼视光学院（生物医学工程学院）、附属眼视光医院
推荐引用方式 GB/T 7714	Pan, Xiafei,Xu, Kai,Wang, Xin,et al. Evening exercise is associated with lower odds of visual field progression in Chinese patients with primary open angle glaucoma[J]. EYE AND VISION,2020,7(1):24-31.
APA	Pan, Xiafei., Xu, Kai., Wang, Xin., Chen, Guofu., Cheng, Huanhuan., ... & Liang, Yuanbo. (2020). Evening exercise is associated with lower odds of visual field progression in Chinese patients with primary open angle glaucoma. EYE AND VISION, 7(1), 24-31.
MLA	Pan, Xiafei,et al."Evening exercise is associated with lower odds of visual field progression in Chinese patients with primary open angle glaucoma".EYE AND VISION 7.1(2020):24-31.