Anti-hypertensive effects of NIP extract in two different rat models

科研成果详情

题名	Anti-hypertensive effects of NIP extract in two different rat models
作者	Chen, Suhong ; Lv, Guiyuan ; Zhang, Xiaodong ; Liu, Xiaoyu ; Zhang, Han ; Zhu, Yunwei ; Wu, Yin ; Liu, Saiyue ; Ni, Zhunan
发表日期	2007
发表期刊	ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION 影响因子和分区
语种	英语
原始文献类型	Article ; Proceedings Paper
关键词	food aid expert system disaster relief monitoring evaluation
摘要	The aim of the study was to evaluate whether laiju extract (LJE) from Semen Raphani and Flos Chrysanthemi has an anti-hypertensive effect in renal hypertensive rat (RHR) and spontaneous hypertensive rat (SHR). LJE was prepared by extracting dried Semen Raphani and Flos Chrysanthemi with 70% ethanol. RHR and SHR models were prepared by standard methods. Forty RERs and 40 SHRs were randomly divided into high LJE (300 mg/kg), moderate LJE (200 mg/kg), low LJE (100 mg/kg) and saline control four groups (n= 10), respectively. Compared with saline control, blood pressure was significantly lowered at 6 and 5 hours in high and moderate LJE respectively in both RHR and SHR groups. However, blood pressure was significantly lowered at 2 and 3 hours in low LJE in both RHR and SHR groups, respectively. Compared with saline control, blood pressure remained significantly lower in SHR in all dosage groups with a single daily dose for 28 days of study. LJE has potential in the prevention management of hypertension. Further studies are needed to identify the active chemical constituents and mechanisms of action of LJE.
出版者	H E C PRESS, HEALTHY EATING CLUB PTY LTD
出版地	MCKINNON
ISSN	0964-7058
EISSN	1440-6047
卷号	16 页码:309-312
页数	4
WOS类目	Nutrition & Dietetics
WOS研究方向	Nutrition & Dietetics
WOS记录号	WOS:000245926500059
收录类别	SCIE ; PUBMED ; CPCI-S
URL	查看原文
PubMed ID	17392125
通讯作者地址	[Lv, Guiyuan]Zhejiang Chinese Med Univ, Inst Mat Med, 548 Binwen Rd, Hangzhou 310053, Zhejiang, Peoples R China.
引用统计	被引频次：6[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/881
专题	第一临床医学院（信息与工程学院）、附属第一医院_中医学
通讯作者	Lv, Guiyuan
作者单位	1.Zhejiang Chinese Med Univ, Inst Mat Med, Hangzhou 310053, Zhejiang, Peoples R China; 2.Wenzhou Med Coll, Acad Tradit Chinese Med, Wenzhou, Peoples R China; 3.State Food & Drug Adm, Ctr Drug Evaluat, Beijing, Peoples R China; 4.Shanghai Univ Tradit Chinese Med, Shanghai, Peoples R China
推荐引用方式 GB/T 7714	Chen, Suhong,Lv, Guiyuan,Zhang, Xiaodong,et al. Anti-hypertensive effects of NIP extract in two different rat models[J]. ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION,2007,16:309-312.
APA	Chen, Suhong., Lv, Guiyuan., Zhang, Xiaodong., Liu, Xiaoyu., Zhang, Han., ... & Ni, Zhunan. (2007). Anti-hypertensive effects of NIP extract in two different rat models. ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION, 16, 309-312.
MLA	Chen, Suhong,et al."Anti-hypertensive effects of NIP extract in two different rat models".ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION 16(2007):309-312.