Antibiotic resistance genes in an urban river as impacted by bacterial community and physicochemical parameters

doi:10.1007/s11356-017-0032-0

科研成果详情

题名	Antibiotic resistance genes in an urban river as impacted by bacterial community and physicochemical parameters
作者	Zhou, Zhen-Chao 1; Zheng, Ji 1; Wei, Yuan-Yuan 1; Chen, Tao 1; Dahlgren, Randy A.2; Shang, Xu3; Chen, Hong 1
发表日期	2017-10
发表期刊	ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Antibiotic resistance genes Urban rivers Physicochemical parameters Microbial community structure High-throughput qPCR
其他关键词	QUATERNARY AMMONIUM-COMPOUNDS ; RISK-ASSESSMENT ; WASTE-WATER ; ESCHERICHIA-COLI ; SEWAGE-SLUDGE ; PEARL RIVER ; CHINA ; RESERVOIRS ; IDENTIFICATION ; ENVIRONMENTS
摘要	Antibiotic resistance genes (ARGs) in urban rivers are a serious public health concern in regions with poorly planned, rapid development. To gain insights into the predominant factors affecting the fate of ARGs in a highly polluted urban river in eastern China, a total of 285 ARGs, microbial communities, and 20 physicochemical parameters were analyzed for 17 sites. A total of 258 unique ARGs were detected using high-throughput qPCR, and the absolute abundance of total ARGs was positively correlated with total organic carbon and total dissolved nitrogen concentrations (P < 0.01). ARG abundance and diversity were greatly altered by microbial community structure. Variation partitioning analysis showed that the combined effects of multiple factors contributed to the profile and dissemination of ARGs, and variation of microbial communities was the major factor affecting the distribution of ARGs. The disparate distribution of some bacteria, including Bacteroides from mammalian gastrointestinal flora, Burkholderia from zoonotic infectious diseases, and Zoogloea from wastewater treatment, indicates that the urban river was strongly influenced by point-source pollution. Results imply that microbial community shifts caused by changes in water quality may lead to the spread of ARGs, and point-source pollution in urban rivers requires greater attention to control the transfer of ARGs between environmental bacteria and pathogens.
资助项目	Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21677121, 41571130064]
出版者	SPRINGER HEIDELBERG
出版地	HEIDELBERG
ISSN	0944-1344
EISSN	1614-7499
卷号	24 期号:30 页码:23753-23762
DOI	10.1007/s11356-017-0032-0
页数	10
WOS类目	Environmental Sciences
WOS研究方向	Environmental Sciences & Ecology
WOS记录号	WOS:000412930300031
收录类别	SCIE ; PUBMED ; SCOPUS
URL	查看原文
Pubmed记录号	28864929
Scopus记录号	2-s2.0-85028757584
通讯作者地址	[Chen, Hong]Department of Environmental Engineering,College of Environmental and Resource Sciences,Zhejiang University,Hangzhou,310058,China
scopus学科分类	Environmental Chemistry;Pollution;Health, Toxicology and Mutagenesis
引用统计	被引频次：86[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/8787
专题	公共卫生与管理学院_水环境应用技术研究所
通讯作者	Chen, Hong
作者单位	1.Department of Environmental Engineering,College of Environmental and Resource Sciences,Zhejiang University,Hangzhou,310058,China; 2.Department of Land,Air and Water Resources,University of California,Davis,95616,United States; 3.Institute of Wenzhou Applied Technology in Environmental Research,Wenzhou Medical University,Wenzhou,325035,China
推荐引用方式 GB/T 7714	Zhou, Zhen-Chao,Zheng, Ji,Wei, Yuan-Yuan,et al. Antibiotic resistance genes in an urban river as impacted by bacterial community and physicochemical parameters[J]. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,2017,24(30):23753-23762.
APA	Zhou, Zhen-Chao., Zheng, Ji., Wei, Yuan-Yuan., Chen, Tao., Dahlgren, Randy A.., ... & Chen, Hong. (2017). Antibiotic resistance genes in an urban river as impacted by bacterial community and physicochemical parameters. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 24(30), 23753-23762.
MLA	Zhou, Zhen-Chao,et al."Antibiotic resistance genes in an urban river as impacted by bacterial community and physicochemical parameters".ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH 24.30(2017):23753-23762.