题名 | Diagnostic Value of Kisspeptin Levels on Early Pregnancy Outcome: a Systematic Review and Meta-analysis |
作者 | |
发表日期 | 2022-12 |
发表期刊 | REPRODUCTIVE SCIENCES 影响因子和分区 |
语种 | 英语 |
原始文献类型 | Review ; Early Access |
关键词 | Kisspeptin Miscarriage hCG Systematic review |
其他关键词 | HUMAN CHORIONIC-GONADOTROPIN ; PROTEIN-COUPLED RECEPTOR ; INVITRO FERTILIZATION ; EMBRYO-TRANSFER ; MISCARRIAGE ; BIOMARKER ; KISS-1 ; GENE |
摘要 | The objective of this study is to investigate whether kisspeptin levels in early pregnancy have a better diagnostic value on early pregnancy outcome as compared with human chorionic gonadotropin (hCG). This study was a systematic review and meta-analysis aiming to investigate the diagnostic value of kisspeptin levels on early pregnancy outcome. The primary outcome was miscarriage or viable intrauterine pregnancy. Five studies were included for systematic review, and three studies were included for meta-analysis. Meta-analysis showed kisspeptin levels had a good diagnostic value with the area under the curve (AUC) 0.902 (0.866, 0.937) when kisspeptin was measured after 6 weeks of gestation. Sensitivity analysis demonstrated kisspeptin levels had a diagnostic value with AUC = 0.881 (0.855, 0.906). hCG levels had a diagnostic value with AUC = 0.834 (0.785, 0.883), which was inferior to the diagnostic value of kisspeptin (mean difference = 0.09 (0.02, 0.16)). Kisspeptin measurement has a potential for comparable or even higher accuracy than hCG in differentiating between miscarriage and viable intrauterine pregnancy after 6 weeks of gestation. |
资助项目 | National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81873835, 82071726] |
出版者 | SPRINGER HEIDELBERG |
出版地 | HEIDELBERG |
ISSN | 1933-7191 |
EISSN | 1933-7205 |
卷号 | 29期号:12页码:3365-3372 |
DOI | 10.1007/s43032-022-00856-8 |
页数 | 8 |
WOS类目 | Obstetrics & Gynecology ; Reproductive Biology |
WOS研究方向 | Obstetrics & Gynecology ; Reproductive Biology |
WOS记录号 | WOS:000761891800004 |
收录类别 | SCIE ; PUBMED ; SCOPUS |
URL | 查看原文 |
PubMed ID | 35212930 |
SCOPUSEID | 2-s2.0-85125171950 |
通讯作者地址 | [Mu, Liangshan]Zhejiang MedicalTech Therapeutics Company,No.665 Yumeng Road,Wenzhou,325200,China ; [Zhang, Hong]Medical Reproductive Center,The Second Affiliated Hospital of Soochow University,No.1055 Sanxiang Road, Gusu District,Suzhou,215026,China |
Scopus学科分类 | Obstetrics and Gynecology |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | https://kms.wmu.edu.cn/handle/3ETUA0LF/8274 |
专题 | 附属第一医院_内分泌科 第一临床医学院(信息与工程学院)、附属第一医院_妇产科学_生殖医学中心 |
通讯作者 | Zhang, Hong; Mu, Liangshan |
作者单位 | 1.Center for Reproductive Medicine,Peking University Third Hospital,No.49 Huayuan North Road, Haidian District,Beijing,100191,China; 2.Zhejiang MedicalTech Therapeutics Company,No.665 Yumeng Road,Wenzhou,325200,China; 3.Department of Endocrinology,The First Affiliated Hospital of Wenzhou Medical University,Wenzhou,325000,China; 4.Reproductive Medicine Center,The First Affiliated Hospital of Wenzhou Medical University,Wenzhou,325000,China; 5.Medical Reproductive Center,The Second Affiliated Hospital of Soochow University,No.1055 Sanxiang Road, Gusu District,Suzhou,215026,China |
推荐引用方式 GB/T 7714 | Hu, Kai-Lun,Chen, Zimiao,Deng, Wenhai,et al. Diagnostic Value of Kisspeptin Levels on Early Pregnancy Outcome: a Systematic Review and Meta-analysis[J]. REPRODUCTIVE SCIENCES,2022,29(12):3365-3372. |
APA | Hu, Kai-Lun., Chen, Zimiao., Deng, Wenhai., Li, Xiaoxue., Ju, Liping., ... & Mu, Liangshan. (2022). Diagnostic Value of Kisspeptin Levels on Early Pregnancy Outcome: a Systematic Review and Meta-analysis. REPRODUCTIVE SCIENCES, 29(12), 3365-3372. |
MLA | Hu, Kai-Lun,et al."Diagnostic Value of Kisspeptin Levels on Early Pregnancy Outcome: a Systematic Review and Meta-analysis".REPRODUCTIVE SCIENCES 29.12(2022):3365-3372. |
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