Elastomeric self-healing antibacterial bioactive nanocomposites scaffolds f or treating skull defect

doi:10.1016/j.apmt.2021.101254

科研成果详情

题名	Elastomeric self-healing antibacterial bioactive nanocomposites scaffolds f or treating skull defect
作者	Li, Yannan 1,2,4; Ge, Juan 6; Luo, Meng 4; Niu, Wen 4; Ling, Xiangwei3; Xu, Ke1; Lin, Cai3; Lei, Bo 4,5; Zhang, Xingxing 1
发表日期	2022-03
发表期刊	APPLIED MATERIALS TODAY 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Bioactive scaffolds Bioactive glass Multifunctional biomaterials Skull defect repair Tissue engineering
其他关键词	CRANIOPLASTY ; SILICA
摘要	The treatment of trauma-induced skull defect is still a challenge, which includes the skull repair while protecting brain tissues. Most of conventional biomaterials for skull repair show the poor elasticity and low osteogenic activity while lacking the antibacterial activity, which are not satisfied for treating traumainduced skull defect. Herein, we report a bioactive elastomeric self-healing antibacterial nanocomposite hydrogel scaffold (PAPB) with good biomineralization activity for enhancing the skull defect reconstruction. The PAPB scaffolds could efficiently match the skull defect morphology, enhance osteogenic differentiation, regenerate the bone tissues. This work suggests the important potential of bioactive elastomeric self-healing scaffolds with antibacterial activity in treating trauma-induced skull defect. (c) 2021 Elsevier Ltd. All rights reserved.
资助项目	Wenzhou Science and Tech-nology Bureau Project of China [ZY2019003, Y2020236]; Medical Health Science and Technology Project of Zhejiang Province of China [2019KY464]
出版者	ELSEVIER
出版地	AMSTERDAM
ISSN	2352-9407
EISSN	2352-9407
卷号	26
DOI	10.1016/j.apmt.2021.101254
页数	11
WOS类目	Materials Science, Multidisciplinary
WOS研究方向	Materials Science
WOS记录号	WOS:000733565300004
收录类别	SCIE ; EI ; SCOPUS
EI入藏号	20220211452160
EI主题词	Bioactive glass
EI分类号	415 Metals, Plastics, Wood and Other Structural Materials ; 461.1 Biomedical Engineering ; 461.2 Biological Materials and Tissue Engineering ; 461.9 Biology ; 462.5 Biomaterials (including synthetics) ; 761 Nanotechnology ; 801.2 Biochemistry ; 812.3 Glass ; 913.5 Maintenance ; 933 Solid State Physics ; 951 Materials Science
URL	查看原文
SCOPUSEID	2-s2.0-85122516068
通讯作者地址	[Zhang, Xingxing]Department of Endocrinology and Metabolism,The First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China ; [Lei, Bo]Frontier Institute of Science and Technology,Xi'an Jiaotong University,Xi'an,710054,China
Scopus学科分类	Materials Science (all)
引用统计	被引频次：4[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/8125
专题	附属第一医院_内分泌科附属第一医院_烧伤科
通讯作者	Lei, Bo; Zhang, Xingxing
作者单位	1.Department of Endocrinology and Metabolism,The First Affiliated Hospital of Wenzhou Medical University,Wenzhou,China; 2.School of Physical Science and Technology,Inner Mongolia University,Hohhot,010021,China; 3.Department of Burn,the First Affiliated Hospital of Wenzhou Medical University,Wenzhou,325000,China; 4.Frontier Institute of Science and Technology,Xi'an Jiaotong University,Xi'an,710054,China; 5.State Key Laboratory for Manufacturing Systems Engineering,Xi'an Jiaotong University,Xi'an,710054,China; 6.National and Local Joint Engineering Research Center of Biodiagnosis and Biotherapy,The Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710000,China
第一作者单位	附属第一医院; 第一临床医学院（信息与工程学院）、附属第一医院
通讯作者单位	附属第一医院; 第一临床医学院（信息与工程学院）、附属第一医院
第一作者的第一单位	附属第一医院
推荐引用方式 GB/T 7714	Li, Yannan,Ge, Juan,Luo, Meng,et al. Elastomeric self-healing antibacterial bioactive nanocomposites scaffolds f or treating skull defect[J]. APPLIED MATERIALS TODAY,2022,26.
APA	Li, Yannan., Ge, Juan., Luo, Meng., Niu, Wen., Ling, Xiangwei., ... & Zhang, Xingxing. (2022). Elastomeric self-healing antibacterial bioactive nanocomposites scaffolds f or treating skull defect. APPLIED MATERIALS TODAY, 26.
MLA	Li, Yannan,et al."Elastomeric self-healing antibacterial bioactive nanocomposites scaffolds f or treating skull defect".APPLIED MATERIALS TODAY 26(2022).