Study on Serological Blood Group Conversion in BM Empty Phase of ABO-incompatible Allogeneic Stem Cell Transplantation

doi:10.7534/j.issn.1009-2137.2016.01.041

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题名	Study on Serological Blood Group Conversion in BM Empty Phase of ABO-incompatible Allogeneic Stem Cell Transplantation
其他题名	Study on Serological Blood Group Conversion in BM Empty Phase of ABO-incompatible Allogeneic Stem Cell Transplantation
作者	Xue-Jiao Cai1; Bi-Le Chen2; Zuo-Ting Xie2; Yin-Cai Ye2
发表日期	2016-02-01
发表期刊	Zhongguo shi yan xue ye xue za zhi 影响因子和分区
语种	英语
原始文献类型	期刊论文
关键词	造血干细胞移植血型血清学血型不合
其他关键词	stem cell transplantation ; serological blood group ; ABO-incompatible
摘要	Objective: To explore the regularity of serological conversion of blood group in BM empty phase of ABO-incompatible allogeneic stem cell transplantation so as to provide the basis for selecting the blood components in blood transfusion. Methods: Before hematpoietic stem cell transplantation (HSCT), the ABO and RhD blood groups of recipients and donors were identified by salt medium tube method and microcolumn gel method; after transplantation the changes of antigen intensity and antibody titer of ABO blood group in patients were periodically detected. Results: After blood group shift of 33 patients received ABO-incompatible allo-HSCT, the consistent rate of positive and regative types in major ABO incompatible group was 100%; the consistent rate of positive and negative types in minor ABO-incompatible group was 33%, no-consistent rate was 66.7%; the consistent rate of positive and negative types in bidirextional ABO incompatible group was 20%, the no-consistent rate was 80%. Conclusion: After ABO-incompatible allo-HSCT, blood group antgen of patients shifts to the blood group of donors, there is a significant difference in the serological indicators between the minor and bidireetional ABO-incompatible patients and normal people.
其他摘要	Objective:To explore the regularity of serological conversion of blood group in BM empty phase of ABO-incompatible allogeneic stem cell transplantation so as to provide the basis for selecting the blood components in blood transfusion. Methods:Before hematpoietic stem cell transplantation (HSCT), the ABO and RhD blood groups of recipients and donors were identified by salt medium tube method and microcolumn gel method; after transplantation the changes of antigen intensity and antibody titer of ABO blood group in patients were periodically detected. Results:After blood group shift of 33 patients received ABO-incompatible allo-HSCT, the consistent rate of positive and regative types in major ABO incompatible group was 100%; the consistent rate of positive and negative types in minor ABO-incompatible group was 33%, no-consistent rate was 66.7%; the consistent rate of positive and negative types in bidirextional ABO incompatible group was 20%, the no-consistent rate was 80%. Conclusion:After ABO-incompatible allo-HSCT, blood group antgen of patients shifts to the blood group of donors, there is a significant difference in the serological indicators between the minor and bidireetional ABO-incompatible patients and normal people.
资助项目	浙江省温州市科技计划项目
ISSN	1009-2137
卷号	24 期号:1 页码:221-4.
DOI	10.7534/j.issn.1009-2137.2016.01.041
页数	4
收录类别	PUBMED ; CSCD ; 万方 ; PKU ; 北大核心 ; ISTIC
学科领域	医药、卫生 ; 临床医学
URL	查看原文
CSCD记录号	CSCD:5630130
PubMed ID	26913424
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/63772
专题	附属第一医院_输血科
作者单位	1.Department of Blood Transfusion, The First Affiliate Hospital of Wenzhou Medical College, Wenzhou 325000, Zhejiang Province, China. E-mail: 942118013@qq.com.; 2.Department of Blood Transfusion, The First Affiliate Hospital of Wenzhou Medical College, Wenzhou 325000, Zhejiang Province, China.
第一作者单位	温州医科大学
第一作者的第一单位	温州医科大学
推荐引用方式 GB/T 7714	Xue-Jiao Cai,Bi-Le Chen,Zuo-Ting Xie,et al. Study on Serological Blood Group Conversion in BM Empty Phase of ABO-incompatible Allogeneic Stem Cell Transplantation[J]. Zhongguo shi yan xue ye xue za zhi,2016,24(1):221-4..
APA	Xue-Jiao Cai, Bi-Le Chen, Zuo-Ting Xie, & Yin-Cai Ye. (2016). Study on Serological Blood Group Conversion in BM Empty Phase of ABO-incompatible Allogeneic Stem Cell Transplantation. Zhongguo shi yan xue ye xue za zhi, 24(1), 221-4..
MLA	Xue-Jiao Cai,et al."Study on Serological Blood Group Conversion in BM Empty Phase of ABO-incompatible Allogeneic Stem Cell Transplantation".Zhongguo shi yan xue ye xue za zhi 24.1(2016):221-4..

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