Impact of chronic prostatitis/chronic pelvic pain syndrome on sperm DNA fragmentation and nucleoprotein transition

科研成果详情

题名	Impact of chronic prostatitis/chronic pelvic pain syndrome on sperm DNA fragmentation and nucleoprotein transition
作者	Yang-Yang Hu; Shun-Shun Cao; Jie-Qiang Lü
发表日期	2013-10-01
发表期刊	Zhonghua nan ke xue = National journal of andrology 影响因子和分区
语种	英语
原始文献类型	English Abstract ; Journal Article
摘要	Objective: To investigate the impact of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) on sperm DNA fragmentation and nucleoprotein transition. Methods: Based on the recommended methods in the WHO Laboratory Manual for the Examination and Processing of Human Semen (5th ed), we conducted routine semen analysis for 65 CP/CPPS patients and 30 healthy men. We also analyzed the results of papanicolaou staining, sperm DNA fragmentation and sperm nucleoprotein transition. Results: Compared with the healthy control males, the CP/CPPS patients showed significant decreases in sperm concentration ([134.05 +/- 99.80] vs [94.75 +/- 92.07]) x 10(6)/ml, P <0.05), the percentage of morphologically normal sperm ([7.26 +/- 2.28] vs [5.61 +/- 3.40]%, P <0.05) and sperm progressive motility ([59.18 +/- 16.06] vs [47.68 +/- 17.62]%, P<0.05), but dramatic increases in sperm DNA fragmentation ([22.92 +/- 11.51] vs [43.58 +/- 17.07%, P<0.01) and sperm nucleoprotein transition ([23.26 +/- 5.97] vs [32.14 +/- 8.79]%, P<0.01). Conclusion: CP/CPPS significantly reduces sperm quality and male fertility.
ISSN	1009-3591
卷号	19 期号:10 页码:907-11.
收录类别	PUBMED
URL	查看原文
PubMed ID	24218945
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/63733
专题	附属第二医院_生殖医学中心
作者单位	Center of Reproductive Medicine, The Second Hospital Affiliated to Wenzhou Medical College, Wenzhou, Zhejiang 325000, China. huyangyang0577@126.com
第一作者单位	附属第二医院_生殖医学中心
第一作者的第一单位	附属第二医院_生殖医学中心
推荐引用方式 GB/T 7714	Yang-Yang Hu,Shun-Shun Cao,Jie-Qiang Lü. Impact of chronic prostatitis/chronic pelvic pain syndrome on sperm DNA fragmentation and nucleoprotein transition[J]. Zhonghua nan ke xue = National journal of andrology,2013,19(10):907-11..
APA	Yang-Yang Hu, Shun-Shun Cao, & Jie-Qiang Lü. (2013). Impact of chronic prostatitis/chronic pelvic pain syndrome on sperm DNA fragmentation and nucleoprotein transition. Zhonghua nan ke xue = National journal of andrology, 19(10), 907-11..
MLA	Yang-Yang Hu,et al."Impact of chronic prostatitis/chronic pelvic pain syndrome on sperm DNA fragmentation and nucleoprotein transition".Zhonghua nan ke xue = National journal of andrology 19.10(2013):907-11..