C1772T polymorphism of hypoxia-inducible factor-1 alpha gene in Han ethnic population from Northern China

doi:10.3785/j.issn.1008-9292.2008.03.009

科研成果详情

题名	C1772T polymorphism of hypoxia-inducible factor-1 alpha gene in Han ethnic population from Northern China
其他题名	C1772T polymorphism of hypoxia-inducible factor-1α gene in Han ethnic population from Northern China
作者	Hai-Ping Liu; Yang Xu; Chun-Yan Jin
发表日期	2008-05-01
发表期刊	Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 影响因子和分区
语种	英语
原始文献类型	Article
关键词	汉族中国多态性单核苷酸等位基因缺氧
摘要	Objective: To analyze the distribution of single nucleotide polymorphism C1772T (SNP/C1772T) in hypoxia-inducible factor -1 alpha (HIF-1 alpha) gene in Han ethnic population from Northern China. Methods: Allele frequencies in a sample of 206 healthy Chinese Hans were determined by polymerase chain reaction followed by restriction fragment length polymorphism. Result: The genotype frequencies of C1772T observed in Chinese Hans were 93 % and 7% for CC and CT respectively; and allele frequencies were 96% and 4 %for C and T respectively. There was significant difference in distribution of allele frequencies between Chinese Hans and Caucasian. Conclusion: The single nucleotide polymorphism of C1772T in HIF-1 alpha gene has difference in different ethnic population.
资助项目	科技部资助项目;
ISSN	1008-9292
卷号	37 期号:3 页码:267-70.
DOI	10.3785/j.issn.1008-9292.2008.03.009
页数	4
收录类别	PUBMED ; SCOPUS ; 万方 ; PKU ; 北大核心 ; ISTIC
URL	查看原文
PubMed ID	18546529
SCOPUSEID	2-s2.0-77950351627
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/63168
专题	体育科学部_运动人体科学系
作者单位	Department of Sports and Human Science, Wenzhou Medical College, Wenzhou 325035, China. liuhaip@126.com
第一作者单位	温州医科大学
第一作者的第一单位	温州医科大学
推荐引用方式 GB/T 7714	Hai-Ping Liu,Yang Xu,Chun-Yan Jin. C1772T polymorphism of hypoxia-inducible factor-1 alpha gene in Han ethnic population from Northern China[J]. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences,2008,37(3):267-70..
APA	Hai-Ping Liu, Yang Xu, & Chun-Yan Jin. (2008). C1772T polymorphism of hypoxia-inducible factor-1 alpha gene in Han ethnic population from Northern China. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 37(3), 267-70..
MLA	Hai-Ping Liu,et al."C1772T polymorphism of hypoxia-inducible factor-1 alpha gene in Han ethnic population from Northern China".Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 37.3(2008):267-70..

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