Intraoperative mitomycin C in dacryocystorhinostomy

doi:10.1097/00002341-200103000-00007

科研成果详情

题名	Intraoperative mitomycin C in dacryocystorhinostomy
作者	Y A You; C T Fang
发表日期	2001-03-01
发表期刊	Ophthalmic plastic and reconstructive surgery 影响因子和分区
语种	英语
原始文献类型	Article
摘要	Purpose: To assess the efficacy of intraoperative mitomycin C (MMC) in external dacryocystorhinostomy (EXT-DCR). Methods: Forty-six cases (50 lacrimal drainage systems [LDS]) with nasolacrimal duct obstruction were randomized into three groups. In the control group, a standard EXT-DCR procedure was performed. In the two MMC groups, a piece of cotton soaked with 0.2 mg/ml MMC (group 1) or 0.5 mg/ml MMC (group 2) was applied to the nasal mucosa and the mucosa of the lacrimal sac in the osteotomy site for 5 minutes. Results: The dacryocystorhinostomy in all patients was patent by irrigation 2 to 3 weeks postoperatively. After a mean follow-up interval of 35.2 +/- 5.3 months, the dacryocystorhinostomy was patent in 15 (83%) of 18 LDS in the control group, 16 (100%) of 16 LDS in group 1, and 15 (94%) of 16 LDS in group 2. The mean ostium sizes were 22.2 +/- 5.0 mm2 in group 1, 20.6 +/- 4.5 mm2 in group 2, and 13.2 +/- 2.7 mm2 in group 3 at the final follow-up visit; the difference between the patients treated with MMC and the control group was statistically significant. There was no statistically significant difference between the two MMC groups, however. No surgical complications occurred. Conclusions: Intraoperative MMC in DCR is a safe and effective adjuvant that helps achieve favorable long-term success rates.
ISSN	0740-9303
卷号	17 期号:2 页码:115-9.
DOI	10.1097/00002341-200103000-00007
收录类别	PUBMED ; SCOPUS
URL	查看原文
PubMed ID	11281583
SCOPUSEID	2-s2.0-0035106555
引用统计	被引频次：55[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/62814
专题	附属第一医院_眼科
作者单位	Department of Ophthalmology, First Affiliated Hospital, Wenzhou Medical College, China.
第一作者单位	附属第一医院_眼科
第一作者的第一单位	附属第一医院_眼科
推荐引用方式 GB/T 7714	Y A You,C T Fang. Intraoperative mitomycin C in dacryocystorhinostomy[J]. Ophthalmic plastic and reconstructive surgery,2001,17(2):115-9..
APA	Y A You, & C T Fang. (2001). Intraoperative mitomycin C in dacryocystorhinostomy. Ophthalmic plastic and reconstructive surgery, 17(2), 115-9..
MLA	Y A You,et al."Intraoperative mitomycin C in dacryocystorhinostomy".Ophthalmic plastic and reconstructive surgery 17.2(2001):115-9..