胸腔感染与血清降钙素原水平变化的相关性分析

doi:10.11816/cn.ni.2014-134213

科研成果详情

题名	胸腔感染与血清降钙素原水平变化的相关性分析
其他题名	Correlation between chest infections and level of serum calcitonin
作者	金良达 1,2; 黄日胜 1,2; 林志毅 1,2; 孙成超3
发表日期	2014
发表期刊	中华医院感染学杂志影响因子和分区
语种	中文
原始文献类型	学术期刊
关键词	胸腔感染血清降钙素原 APACHEⅡ评分相关性
其他关键词	Chest infection ; Serum calcitonin ; APACHE Ⅱ score ; Correlation
摘要	目的分析胸腔感染与血清降钙素原水平变化的相关性,以探讨血清降钙素原的检测在胸腔感染诊治中的临床应用价值。方法选取医院收治的胸腔感染患者480例,根据患者感染的严重程度,将其分为重症感染组189例及非重症感染组291例,同时选取同期在医院体检的健康受试者100名为对照组,所有受试者均接受血清降钙素原水平的检测,对比3组受试者的血清降钙素原水平和APACHEⅡ评分结果,并对比胸腔感染患者治疗前后血清降钙素原水平的变化。结果重症感染组的血清降钙素原水平为(67.51±12.7)μg/L,显著高于非重症感染组和对照组(P<0.05),非重症感染组的血清降钙素原水平为(17.21±5.38)μg/L,显著高于对照组(P<0.05);重症感染组的APACHEⅡ评分为(23.22±5.32)分,显著高于非重症感染组和对照组(P<0.05),非重症感染组的APACHEⅡ评分为(3.21±1.90)分,与对照组对比,差异无统计学意义;Pearson相关分析结果显示,重症胸腔感染和非重症胸腔感染的血清降钙素原水平和APACHEⅡ评分结果呈正相关(P<0.05);胸腔感染治疗前的血清降钙素原水平为(40.23±8.91)μg/L,显著高于胸腔感染治疗后和对照组(P<0.05),胸腔感染治疗后的血清降钙素原水平为(6.31±1.93)μg/L,与对照组对比差异无统计学意义。结论血清降钙素原的检测有助于早期诊断胸腔感染,同时对胸腔感染严重程度的判断以及治疗策略的制定均有重要的指导意义。
其他摘要	OBJECTIVE To analyze the correlation between the chest infections and the level of serum calcitonin so as to explore the clinical value of serum calcitonin test in diagnosis of chest infections. METHODS A total of 480 patients with chest infections were recruited as the study objects and divided into the severe infection group with 189 cases and the non-severe infection group with 291 cases according to the severity of the infections, meanwhile, 100 healthy people who undertook physical examination were assigned as the control group, then all the participants received the test of serum calcitonin, the level of serum calcitonin and the APACHE Ⅱ score were compared among the three groups of participants, and the level of serum calcitonin of the patients with chest infections was observed and compared before and after the treatment. RESULTS The level of serum calcitonin of the severe infection group was (67. 51 ± 12. 7)μg/L,significantly higher than that of the non-severe infection group and the control group (P<0. 05) ; the level of serum calcitonin of the non-severe infection group was (17. 21 ± 5. 38) μg/L, significantly higher than that of the control group (P<0. 05). The APACHE Ⅱ score of the severe infection group was (23. 22±5. 32)points, significantly higher than that of the non-server infection group and the control group (P<0. 05) ; the APACHE Ⅱ score of the non-severe infection group was (3. 21 ± l. 90) points, as compared with the control group, the difference was not significant. The result of Pearson analysis indicated that the level of serum calcitonin of the patients with severe chest infections and the patients with non-severe chest infections was positively correlated with the APACHE Ⅱ score (P<0. 05). The level of serum calcitonin was (40. 23 ±8. 91)μg/L before the treatment of chest infections, significantly higher than that after the treatment of chest infections and that of the control group (P<0. 05) ; the level of serum calcitonin was (6. 31 ± 1. 93)μg/L after the treatment of chest infections, as compared with the control group, the difference was not significant. CONCLUSION The serum calcitonin test is conducive to the early diagnosis of chest infections, and it has great significance to determine the severity of chest infections and to formulate treatment strategies.
资助项目	温州市科技局科技计划基金项目（Y20120031）
ISSN	1005-4529
卷号	24 期号:18 页码:4668-4670
DOI	10.11816/cn.ni.2014-134213
页数	3
收录类别	CNKI ; 万方 ; 维普 ; 北大核心 ; PKU ; CSCD ; ISTIC
学科领域	医药、卫生 ; 临床医学
URL	查看原文
CSCD记录号	CSCD:5233736
引用统计
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/51223
专题	附属第一医院其他_定理临床学院（温州市中心医院）
作者单位	1.温州医科大学定理临床学院; 2.温州市中心医院胸外科; 3.温州医科大学附属第一医院心胸外科
第一作者单位	定理临床学院（温州市中心医院）
第一作者的第一单位	定理临床学院（温州市中心医院）
推荐引用方式 GB/T 7714	金良达,黄日胜,林志毅,等. 胸腔感染与血清降钙素原水平变化的相关性分析[J]. 中华医院感染学杂志,2014,24(18):4668-4670.
APA	金良达, 黄日胜, 林志毅, & 孙成超. (2014). 胸腔感染与血清降钙素原水平变化的相关性分析. 中华医院感染学杂志, 24(18), 4668-4670.
MLA	金良达,et al."胸腔感染与血清降钙素原水平变化的相关性分析".中华医院感染学杂志 24.18(2014):4668-4670.

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