Evaluation of the Effect of Nutritional Intervention on Patients with Nasopharyngeal Carcinoma

doi:10.1155/2022/2531671

科研成果详情

题名	Evaluation of the Effect of Nutritional Intervention on Patients with Nasopharyngeal Carcinoma
作者	Lin, Fan1; Ren, Huijun 1; Lin, Fenfen2; Pan, Zhaohu 3; Wu, Liping 1; Yang, Neng 1
发表日期	2022-03-11
发表期刊	Journal of healthcare engineering 影响因子和分区
语种	英语
原始文献类型	Article
关键词	Cells Chemotherapy Cytology Diseases Linear regression Nursing Nutrition Population statistics Tumors Biochemical indicators Body measurements Cancer patients Clinical treatments Inclusion and exclusions Intensity-modulated radiotherapy Measurement indicators Nasopharyngeal cancer Nasopharyngeal carcinoma Nutritional indices
其他关键词	CANCER
摘要	Aim:The paper aims to combine mathematical statistics to assess the effect of nutritional intervention in the population of nasopharyngeal cancer patients. Methodology. After following the inclusion and exclusion criteria, a total of 120 patients with nasopharyngeal carcinoma were selected. All patients are treated with intensity-modulated radiotherapy (IMRT). The nurse collects relevant clinical treatment data during the radiotherapy of the patient. After the patient's radiotherapy, the nurse remeasures the patient's nutritional status indicators. Three months after the completion of radiotherapy, the patient will be reexamined by MRI, and the radiotherapist will assess the patient's radiosensitivity based on the results of the MRI examination. All the blood biochemical indicators and body measurement indicators were also assessed and coordinated with nasopharyngeal carcinoma patients. This study performs multiple linear regression analysis on treatment-related factors that affect nutritional status during radiotherapy. Results:The experimental results showed that the side effects of radiotherapy are independent influencing factors of nutritional status. Radiotherapy damages the DNA of cells, so that cells cannot continue to divide and grow, and all cells in the treatment area were affected by radiation. The standard radiotherapy treatment is quite long, and the oral cavity, throat, and parotid gland, are all within the irradiation range. In addition to killing the tumor cells, the radiation can also cause certain damage to the surrounding tissues of the tumor. This article takes radiosensitivity as the dependent variable (insensitivity = 0; sensitivity = 1) and takes the nutritional index NI, age, gender, education level, marriage, smoking, chronic disease history, TNM staging, whether the chemotherapy steps are the same or not, GTVnx prescription dose, and the number of radiotherapies as independent variables. AMC, albumin, hemoglobin, serum prealbumin, and transferrin are all correlated with radiosensitivity, which is consistent with the results of most studies. The results of multivariate logistic regression analysis showed that nutritional index (NI) was correlated with the radiosensitivity of nasopharyngeal carcinoma. Conclusion:Finally, this paper concludes that nutritional intervention has a certain effect on the treatment of patients with nasopharyngeal carcinoma.
资助项目	Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University
出版者	HINDAWI LTD
出版地	LONDON
ISSN	2040-2295
EISSN	2040-2309
卷号	2022 页码:2531671
DOI	10.1155/2022/2531671
页数	10
WOS类目	Health Care Sciences & Services
WOS研究方向	Health Care Sciences & Services
WOS记录号	WOS:000779486100006
收录类别	PUBMED ; SCOPUS ; SCIE ; EI
EI入藏号	20221311867427
EI主题词	Radiotherapy
EI分类号	461.2 Biological Materials and Tissue Engineering ; 461.6 Medicine and Pharmacology ; 461.7 Health Care ; 461.9 Biology ; 622.3 Radioactive Material Applications ; 922.2 Mathematical Statistics
URL	查看原文
PubMed ID	35310190
PMC记录号	PMC8933072
SCOPUSEID	2-s2.0-85126712023
通讯作者地址	[Yang, Neng]Department of Otolaryngology,Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University,Zhejiang,Taizhou,317000,China
Scopus学科分类	Biotechnology;Surgery;Biomedical Engineering;Health Informatics
引用统计	被引频次[WOS]：0 [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/33863
专题	其他_附属台州医院（浙江省台州医院）
通讯作者	Yang, Neng
作者单位	1.Department of Otolaryngology,Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University,Zhejiang,Taizhou,317000,China; 2.Operating Room,Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University,Zhejiang,Taizhou,317000,China; 3.Department of Otorhinolaryngology,Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University,Zhejiang,Taizhou,317000,China
第一作者单位	其他_附属台州医院（浙江省台州医院）
通讯作者单位	其他_附属台州医院（浙江省台州医院）
第一作者的第一单位	其他_附属台州医院（浙江省台州医院）
推荐引用方式 GB/T 7714	Lin, Fan,Ren, Huijun,Lin, Fenfen,et al. Evaluation of the Effect of Nutritional Intervention on Patients with Nasopharyngeal Carcinoma[J]. Journal of healthcare engineering,2022,2022:2531671.
APA	Lin, Fan, Ren, Huijun, Lin, Fenfen, Pan, Zhaohu, Wu, Liping, & Yang, Neng. (2022). Evaluation of the Effect of Nutritional Intervention on Patients with Nasopharyngeal Carcinoma. Journal of healthcare engineering, 2022, 2531671.
MLA	Lin, Fan,et al."Evaluation of the Effect of Nutritional Intervention on Patients with Nasopharyngeal Carcinoma".Journal of healthcare engineering 2022(2022):2531671.