Reply to: Comments on &quot;Nomograms based on inflammatory biomarkers for predicting tumor grade and micro-vascular invasion in stage I/II hepatocellular carcinoma&quot;

doi:10.1042/BSR20193401

科研成果详情

题名	Reply to: Comments on "Nomograms based on inflammatory biomarkers for predicting tumor grade and micro-vascular invasion in stage I/II hepatocellular carcinoma"
作者	Peng Li1; Wei Huang 2; Feng Wang 2; Ye-Fang Ke 2; Lin Gao 2; Ke-Qing Shi3; Meng-Tao Zhou2; Bi-Cheng Chen2
发表日期	2019-12-20
发表期刊	Bioscience reports 影响因子和分区
语种	英语
原始文献类型	Letter ; Comment
关键词	hepatocellular carcinoma inflammatory biomarkers micro-vascular invasion nomogram tumor grade.
其他关键词	LYMPHOCYTE RATIO ; PROGNOSTIC VALUE ; NEUTROPHIL ; VALIDATION ; SURVIVAL
摘要	We appreciate to receive commentary from Dr Guangtong Deng and Dr Liang Xiao to our article, "Nomograms based on inflammatory biomarkers for predicting tumor grade and micro-vascular invasion in stage I/II hepatocellular carcinoma". First, neutrophil-to-lymphocyte ratio (NLR) and derived NLR (dNLR) are two different parameters. Some studies show that NLR is inconsistent with dNRL in prognostic value through multivariate Cox regression, therefore, it is reasonable that both NLR and dNLR entered into multivariate analysis simultaneously. Second, it is common that articles of predictive nomograms turned continuous variables into categorical variables. The reason is that the categorization of patient clinical variables is beneficial to doctors to make decisions based on the risk level of individual patients in clinical. At last, multicenter validation is quite difficult and we have listed the shortcomings in the limitations of our article. Further validation will need the joint efforts by other institutions.
出版者	PORTLAND PRESS LTD
ISSN	1573-4935
EISSN	1573-4935
卷号	39 期号:12 页码:BSR20193401.
DOI	10.1042/BSR20193401
页数	2
WOS类目	Biochemistry & Molecular Biology ; Cell Biology
WOS研究方向	Biochemistry & Molecular Biology ; Cell Biology
WOS记录号	WOS:000504499000001
收录类别	PUBMED ; SCIE
URL	查看原文
PubMed ID	31710086
PMC记录号	PMC6893163
通讯作者地址	[Chen, Bi-Cheng]Wenzhou Med Univ, Affiliated Hosp 1, Key Lab Diag & Treatment Severe Hepatopancreat Di, Wenzhou, Peoples R China.
引用统计	被引频次[WOS]：0 [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/33598
专题	附属第一医院_病理科附属第一医院第一临床医学院（信息与工程学院）、附属第一医院_精准医学中心实验室
作者单位	1.Department of Pathology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.; 2.Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.; 3.Precision Medical Center Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
第一作者单位	附属第一医院_病理科
通讯作者单位	附属第一医院
第一作者的第一单位	附属第一医院_病理科
推荐引用方式 GB/T 7714	Peng Li,Wei Huang,Feng Wang,et al. Reply to: Comments on "Nomograms based on inflammatory biomarkers for predicting tumor grade and micro-vascular invasion in stage I/II hepatocellular carcinoma"[J]. Bioscience reports,2019,39(12):BSR20193401..
APA	Peng Li., Wei Huang., Feng Wang., Ye-Fang Ke., Lin Gao., ... & Bi-Cheng Chen. (2019). Reply to: Comments on "Nomograms based on inflammatory biomarkers for predicting tumor grade and micro-vascular invasion in stage I/II hepatocellular carcinoma". Bioscience reports, 39(12), BSR20193401..
MLA	Peng Li,et al."Reply to: Comments on "Nomograms based on inflammatory biomarkers for predicting tumor grade and micro-vascular invasion in stage I/II hepatocellular carcinoma"".Bioscience reports 39.12(2019):BSR20193401..