Zili He1,2; Shuang Zou1; Jiayu Yin1; Zhengzheng Gao1; Yanlong Liu1; Yanqing Wu3; Huacheng He3; Yulong Zhou2; Qingqing Wang1,2; Jiawei Li1,2; Fenzan Wu4; Hua-Zi Xu2; Xiaofeng Jia5,6,7; Jian Xiao8,9

1.Molecular Pharmacology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China.;
2.Department of Orthopaedics Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China.;
3.The Institute of Life Sciences, Wenzhou University, Wenzhou, 325035, China.;
4.Department of Neurosurgery, Affiliated Cixi People's Hospital, Wenzhou Medical University, Ningbo, 315300, China.;
5.Department of Orthopaedics Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China. xjia@som.umaryland.edu.;
6.Department of Neurosurgery, Orthopaedics, Anatomy Neurobiology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA. xjia@som.umaryland.edu.;
7.Department of Biomedical Engineering, Anesthesiology & Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA. xjia@som.umaryland.edu.;
8.Molecular Pharmacology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China. xfxj2000@126.com.;
9.Department of Orthopaedics Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China. xfxj2000@126.com.