Reply to: Comments on Nomograms based on inflammatory biomarkers for predicting tumor grade and micro-vascular invasion in stage I/II hepatocellular carcinoma

doi:10.1042/BSR20193401

科研成果详情

名称	Reply to: Comments on Nomograms based on inflammatory biomarkers for predicting tumor grade and micro-vascular invasion in stage I/II hepatocellular carcinoma
作者	Li, Peng1; Huang, Wei 2; Wang, Feng 2; Ke, Ye-Fang 2; Gao, Lin 2; Shi, Ke-Qing3; Zhou, Meng-Tao2; Chen, Bi-Cheng2
发表期刊	BIOSCIENCE REPORTS
语种	英语
原始文献类型	Letter
其他关键词	LYMPHOCYTE RATIO ; PROGNOSTIC VALUE ; NEUTROPHIL ; VALIDATION ; SURVIVAL
摘要	We appreciate to receive commentary from Dr Guangtong Deng and Dr Liang Xiao to our article, Nomograms based on inflammatory biomarkers for predicting tumor grade and micro-vascular invasion in stage I/II hepatocellular carcinoma. First, neutrophil-to-lymphocyte ratio (NLR) and derived NLR (dNLR) are two different parameters. Some studies show that NLR is inconsistent with dNRL in prognostic value through multivariate Cox regression, therefore, it is reasonable that both NLR and dNLR entered into multivariate analysis simultaneously. Second, it is common that articles of predictive nomograms turned continuous variables into categorical variables. The reason is that the categorization of patient clinical variables is beneficial to doctors to make decisions based on the risk level of individual patients in clinical. At last, multicenter validation is quite difficult and we have listed the shortcomings in the limitations of our article. Further validation will need the joint efforts by other institutions.
出版者	PORTLAND PRESS LTD
出版地	LONDON
ISSN	0144-8463
EISSN	1573-4935
卷号	39
期号	12
DOI	10.1042/BSR20193401
页数	2
WOS类目	Biochemistry & Molecular Biology ; Cell Biology
WOS研究方向	Biochemistry & Molecular Biology ; Cell Biology
WOS记录号	WOS:000504499000001
收录类别	SCIE ; SCOPUS
发布日期	2019-12-04
URL	查看原文
PubMed ID	31710086
通讯作者地址	[Chen, Bi-Cheng]Wenzhou Med Univ, Affiliated Hosp 1, Key Lab Diag & Treatment Severe Hepatopancreat Di, Wenzhou, Peoples R China.
Scopus学科分类	Biophysics;Biochemistry;Molecular Biology;Cell Biology
SCOPUSEID	2-s2.0-85076063263
引用统计	被引频次[WOS]：0 [WOS记录] [WOS相关记录]
文献类型	其他
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/32177
专题	附属第一医院_病理科附属第一医院第一临床医学院（信息与工程学院）、附属第一医院_精准医学中心实验室
通讯作者	Chen, Bi-Cheng
作者单位	1.Wenzhou Med Univ, Affiliated Hosp 1, Dept Pathol, Wenzhou, Peoples R China; 2.Wenzhou Med Univ, Affiliated Hosp 1, Key Lab Diag & Treatment Severe Hepatopancreat Di, Wenzhou, Peoples R China; 3.Wenzhou Med Univ, Affiliated Hosp 1, Precis Med Ctr Lab, Wenzhou, Peoples R China
第一作者单位	附属第一医院_病理科
通讯作者单位	附属第一医院
推荐引用方式 GB/T 7714	Li, Peng,Huang, Wei,Wang, Feng,et al. Reply to: Comments on Nomograms based on inflammatory biomarkers for predicting tumor grade and micro-vascular invasion in stage I/II hepatocellular carcinoma. 2019.