The effect of cigarette smoking on vitamin D level and depression in male patients with acute ischemic stroke

doi:10.1016/j.comppsych.2015.09.006

科研成果详情

题名	The effect of cigarette smoking on vitamin D level and depression in male patients with acute ischemic stroke
作者	Ren, Wenwei; Gu, Yingying; Zhu, Lin; Wang, Liping; Chang, Yaling; Yan, Mengjiao; Han, Bin; He, Jincai
发表日期	2016-02
发表期刊	COMPREHENSIVE PSYCHIATRY 影响因子和分区
语种	英语
原始文献类型	Article
其他关键词	RISK-FACTOR ; PSYCHIATRIC-DISORDERS ; 25-HYDROXYVITAMIN D ; GENERAL-POPULATION ; SUICIDE ATTEMPTERS ; D SUPPLEMENTATION ; BIPOLAR DISORDER ; MAJOR DEPRESSION ; TOBACCO SMOKING ; IMMUNE-SYSTEM
摘要	Objective: The association between low vitamin D levels and depression has been well documented in nonstroke subjects. Accumulating evidence shows that low vitamin D levels may be also associated with depression post stroke. Cigarette smoking was associated with lower vitamin D levels. The purposes of this study were to compare vitamin D levels in smokers to nonsmokers and examine the association between vitamin D levels and depression symptoms in patients with acute ischemic stroke. Materials and methods: Serum levels of 25-hydroxyvitamin D [25(OH)D] were measured in 194 males within 24 h after admission: 116 smokers and 78 nonsmokers. Depression symptoms were assessed with the 17-item Hamilton Depression Scale (HAMD-17). Patients with the HAMD-17 score >7 were identified to have depression symptoms. Results: The chi-square test showed that the frequency of depression in the smoker group was 23.3% (27/116), which was significantly higher than that in the nonsmoker group (11.5% = 9/78), with an odds ratios (OR) of 2.33 (95% CI: 1.03-5.27; chi(2) = 4.25, df = 1, p = 0.039, phi = 0.15). Vitamin D levels were significantly lower in smokers than in nonsmokers (52.4 +/- 20.8 vs 61.7 +/- 19.2; F = 9.88, p = 0.002), with an effect size of 0.05 (eta(2)(p)). Patients with depression symptoms showed lower vitamin D levels than those with no depression symptoms (49.2 +/- 19.6 vs 57.7 +/- 20.6; F = 5.03, p = 0.03), with an effect size of 0.03 (eta(2)(p)). Conclusion: Higher rates of depression in smokers with acute ischemic stroke may be associated with lower vitamin D levels induced by smoking. (C) 2015 Elsevier Inc. All rights reserved.
资助项目	National Key Technologies R&D Program from Ministry of Science and Technology of the People's Republic of China [2009BAI77B06]; Wenzhou Municipal Sci-Tech Bureau Program [H20100021]
出版者	W B SAUNDERS CO-ELSEVIER INC
出版地	PHILADELPHIA
ISSN	0010-440X
EISSN	1532-8384
卷号	65 页码:9-14
DOI	10.1016/j.comppsych.2015.09.006
页数	6
WOS类目	Psychiatry
WOS研究方向	Psychiatry
WOS记录号	WOS:000368752800002
收录类别	SSCI ; SCIE ; PUBMED ; SCOPUS
URL	查看原文
PubMed ID	26773985
SCOPUSEID	2-s2.0-84954306666
社科自定义期刊分类	D类
通讯作者地址	[He, Jincai]Department of Neurology,First Affiliated Hospital of Wenzhou Medical University,Wenzhou, Zhejiang Province,325000,China
Scopus学科分类	Clinical Psychology;Psychiatry and Mental Health
引用统计	被引频次：26[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/2955
专题	附属第一医院
通讯作者	He, Jincai
作者单位	Department of Neurology,First Affiliated Hospital of Wenzhou Medical University,Wenzhou, Zhejiang Province,325000,China
第一作者单位	附属第一医院
通讯作者单位	附属第一医院
第一作者的第一单位	附属第一医院
推荐引用方式 GB/T 7714	Ren, Wenwei,Gu, Yingying,Zhu, Lin,et al. The effect of cigarette smoking on vitamin D level and depression in male patients with acute ischemic stroke[J]. COMPREHENSIVE PSYCHIATRY,2016,65:9-14.
APA	Ren, Wenwei., Gu, Yingying., Zhu, Lin., Wang, Liping., Chang, Yaling., ... & He, Jincai. (2016). The effect of cigarette smoking on vitamin D level and depression in male patients with acute ischemic stroke. COMPREHENSIVE PSYCHIATRY, 65, 9-14.
MLA	Ren, Wenwei,et al."The effect of cigarette smoking on vitamin D level and depression in male patients with acute ischemic stroke".COMPREHENSIVE PSYCHIATRY 65(2016):9-14.