Childhood Trauma and Insomnia Increase Suicidal Ideation in Schizophrenia Patients: A Cross-Sectional Study

doi:10.3389/fpsyt.2021.769743

科研成果详情

题名	Childhood Trauma and Insomnia Increase Suicidal Ideation in Schizophrenia Patients: A Cross-Sectional Study
作者	Zhang, Yaoyao1; Fang, Xinyu 2; Tang, Bei 3; Fan, Kaili 1; Wen, Na 4; Zhao, Ke1; Xu, Weiqian 5; Tang, Wei 1,2; Chen, Yi 4
发表日期	2021-11-11
发表期刊	FRONTIERS IN PSYCHIATRY 影响因子和分区
语种	英语
原始文献类型	Article
关键词	suicide childhood maltreatment schizophrenia insomnia physical neglect
其他关键词	RISK-FACTORS ; ADULTS ; SCALE ; MALTREATMENT ; MORTALITY
摘要	Objectives: This study aimed to investigate the effect of childhood trauma, especially its specific dimensions, and clinical risk factors for suicidal ideation in patients with schizophrenia.Methods: A total of 83 inpatients with schizophrenia were enrolled and divided into two groups: with suicidal ideation (n = 33) and without suicidal ideation (n = 50). All participants were administered the Childhood Trauma Questionnaire-Short Form, the Insomnia Severity Index, the Beck Scale for Suicide Ideation, the Modified Overt Aggression Scales, the auditory hallucination rating scale, the Hamilton Rating Scale of Depression and the Positive and Negative Syndrome Scale.Results: In our sample, 39.8% of the subjects had suicidal ideation, and 60.6% of them had suffered from childhood trauma. Patients with suicidal ideation had a higher Insomnia Severity Index score, Physical neglect score, the Childhood Trauma Questionnaire-Short Form total score (all P < 0.05) compared to those without. The logistic regression analysis revealed that physical neglect in Childhood Trauma Questionnaire was significantly associated with suicidal ideation (OR = 5.46, P < 0.05, 95% CI = 0.007-0.483). Further stepwise multiple linear regression identified that insomnia (beta = 0.272, P = 0.011) and physical neglect (beta = 0.257, P = 0.017) were strong risk factors for the severity of suicidal ideation in patients with schizophrenia. Mediation analysis showed that insomnia played a complete mediating role between physical neglect and suicidal ideation.Conclusion: Our results indicate that childhood maltreatment of physical neglect is a strong independent risk factor for suicidal ideation in schizophrenia. The risk is probably aggravated by the poor quality of sleep. Early screening and psychosocial treatment are recommended for psychotic individuals with a trauma history.
资助项目	Program of Wenzhou[Y20190478];
出版者	FRONTIERS MEDIA SA
出版地	LAUSANNE
ISSN	1664-0640
卷号	12 页码:769743
DOI	10.3389/fpsyt.2021.769743
页数	7
WOS类目	Psychiatry
WOS研究方向	Psychiatry
WOS记录号	WOS:000725601900001
收录类别	SSCI ; SCIE ; PUBMED ; SCOPUS
URL	查看原文
PubMed ID	34858237
PMC记录号	PMC8631870
SCOPUSEID	2-s2.0-85120716428
社科自定义期刊分类	E类
通讯作者地址	[Tang, Wei]Department of Psychiatry,Wenzhou Medical University,Wenzhou,China ; [Chen, Yi]Department of Psychiatry,The Affiliated Kangning Hospital of Wenzhou Medical University,Wenzhou,China ; [Xu, Weiqian]Department of Psychiatry,The Second People's Hospital of Taizhou,Taizhou,China
Scopus学科分类	Psychiatry and Mental Health
引用统计	被引频次[WOS]：0 [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.wmu.edu.cn/handle/3ETUA0LF/2690
专题	精神医学学院_精神医学系第一临床医学院（信息与工程学院）、附属第一医院_精神病与精神卫生学其他_附属康宁医院（温州市康宁医院）
通讯作者	Xu, Weiqian; Tang, Wei; Chen, Yi
作者单位	1.Department of Psychiatry,Wenzhou Medical University,Wenzhou,China; 2.Department of Psychiatry,Affiliated Nanjing Brain Hospital,Nanjing Medical University,Nanjing,China; 3.Children's Hospital of Nanjing Medical University,Nanjing,China; 4.Department of Psychiatry,The Affiliated Kangning Hospital of Wenzhou Medical University,Wenzhou,China; 5.Department of Psychiatry,The Second People's Hospital of Taizhou,Taizhou,China
第一作者单位	精神病与精神卫生学
通讯作者单位	精神病与精神卫生学; 附属康宁医院（温州市康宁医院）
第一作者的第一单位	精神病与精神卫生学
推荐引用方式 GB/T 7714	Zhang, Yaoyao,Fang, Xinyu,Tang, Bei,et al. Childhood Trauma and Insomnia Increase Suicidal Ideation in Schizophrenia Patients: A Cross-Sectional Study[J]. FRONTIERS IN PSYCHIATRY,2021,12:769743.
APA	Zhang, Yaoyao., Fang, Xinyu., Tang, Bei., Fan, Kaili., Wen, Na., ... & Chen, Yi. (2021). Childhood Trauma and Insomnia Increase Suicidal Ideation in Schizophrenia Patients: A Cross-Sectional Study. FRONTIERS IN PSYCHIATRY, 12, 769743.
MLA	Zhang, Yaoyao,et al."Childhood Trauma and Insomnia Increase Suicidal Ideation in Schizophrenia Patients: A Cross-Sectional Study".FRONTIERS IN PSYCHIATRY 12(2021):769743.